Detailed information NTG0201568

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB466_RS09540
• Genome accession: NZ_CP017677
• Coordinates: 1895574..1896617 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CFSAN007894
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1890574..1901617

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB466_RS09510 (AB466_09340)	-	1890995..1892251 (-)	1257	WP_001795108.1	aminopeptidase	-
AB466_RS09515 (AB466_09345)	-	1892254..1892454 (-)	201	WP_000180460.1	DUF1128 family protein	-
AB466_RS09520 (AB466_09350)	-	1892601..1893065 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB466_RS09525 (AB466_09355)	-	1893072..1893347 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AB466_RS09530 (AB466_09360)	-	1893625..1894842 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
AB466_RS09535 (AB466_09365)	vraR	1894955..1895584 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
AB466_RS09540 (AB466_09370)	vraS	1895574..1896617 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AB466_RS09545 (AB466_09375)	liaF	1896614..1897315 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB466_RS09550 (AB466_09380)	-	1897330..1897716 (-)	387	WP_001110179.1	hypothetical protein	-
AB466_RS09555 (AB466_09385)	map	1897933..1898691 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB466_RS09565 (AB466_09395)	-	1899222..1900208 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
AB466_RS09570 (AB466_09400)	-	1900639..1901052 (-)	414	WP_001557448.1	hypothetical protein	-
AB466_RS09575 (AB466_09405)	-	1901081..1901191 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=201568 AB466_RS09540 WP_001017131.1 1895574..1896617(-) (vraS) [Staphylococcus aureus strain CFSAN007894]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=201568 AB466_RS09540 WP_001017131.1 1895574..1896617(-) (vraS) [Staphylococcus aureus strain CFSAN007894]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1