Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   Spy49_1188c Genome accession   CP000829
Coordinates   1182487..1183524 (-) Length   345 a.a.
NCBI ID   ACI61476.1    Uniprot ID   -
Organism   Streptococcus pyogenes NZ131     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1177487..1188524
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Spy49_1184 - 1178237..1178863 (+) 627 ACI61472.1 Type IV prepilin peptidase-like protein -
  Spy49_1185c - 1178945..1180024 (-) 1080 ACI61473.1 hypothetical protein -
  Spy49_1186c - 1180028..1180648 (-) 621 ACI61474.1 hypothetical protein -
  Spy49_1187c - 1181096..1182073 (-) 978 ACI61475.1 Ribose operon repressor -
  Spy49_1188c sepM 1182487..1183524 (-) 1038 ACI61476.1 ATP-dependent protease La Regulator
  Spy49_1189c kdtB 1183511..1184002 (-) 492 ACI61477.1 Phosphopantetheine adenylyltransferase -
  Spy49_1190c - 1183992..1184531 (-) 540 ACI61478.1 Conserved hypothetical protein -
  Spy49_1191c asnA 1184654..1185646 (-) 993 ACI61479.1 Aspartate--ammonia ligase -
  Spy49_1192c arcC 1185959..1186909 (-) 951 ACI61480.1 Carbamate kinase -
  Spy49_1193c - 1186929..1188260 (-) 1332 ACI61481.1 Xaa-His dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37541.20 Da        Isoelectric Point: 9.5788

>NTDB_id=20153 Spy49_1188c ACI61476.1 1182487..1183524(-) (sepM) [Streptococcus pyogenes NZ131]
MKRLNKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPITTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=20153 Spy49_1188c ACI61476.1 1182487..1183524(-) (sepM) [Streptococcus pyogenes NZ131]
ATGAAAAGACTTAACAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTATTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.696

100

0.687

Multiple sequence alignment