Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CGL27_RS18500 Genome accession   NZ_CP022545
Coordinates   4470854..4471492 (+) Length   212 a.a.
NCBI ID   WP_078641502.1    Uniprot ID   -
Organism   Streptomyces sp. 11-1-2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4465854..4476492
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGL27_RS18480 (CGL27_18195) - 4466748..4468295 (-) 1548 WP_119988555.1 PH domain-containing protein -
  CGL27_RS18485 (CGL27_18200) - 4468292..4468791 (-) 500 Protein_3681 PH domain-containing protein -
  CGL27_RS18490 (CGL27_18205) - 4468868..4469413 (-) 546 WP_240450551.1 hypothetical protein -
  CGL27_RS18495 (CGL27_18210) - 4469605..4470849 (+) 1245 WP_119988561.1 sensor histidine kinase -
  CGL27_RS18500 (CGL27_18215) vraR 4470854..4471492 (+) 639 WP_078641502.1 response regulator transcription factor Regulator
  CGL27_RS18505 (CGL27_18220) - 4471592..4474402 (-) 2811 WP_119988564.1 LuxR family transcriptional regulator -
  CGL27_RS18510 (CGL27_18225) - 4474506..4475267 (-) 762 WP_078641504.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 22377.72 Da        Isoelectric Point: 5.3921

>NTDB_id=201505 CGL27_RS18500 WP_078641502.1 4470854..4471492(+) (vraR) [Streptomyces sp. 11-1-2]
MPGNPSGPIRVLLADDHPVVREGLSAMLESAEGITVVGQAGSGEEAVVQAVALRPDITLLDLRMGGMDGVEATGQILRQV
PGCKVVIVTTYEDDSDILRAVEAGAAGYLLKGSSRQELIDAVQTAARGETVLTPSLAGKLFRSRTVEPSPLSGREREVLR
LVGRGLTNAEIGAELFVSEATVKTHLLRSFKKLGVSDRTAAVMKAMERGFLS

Nucleotide


Download         Length: 639 bp        

>NTDB_id=201505 CGL27_RS18500 WP_078641502.1 4470854..4471492(+) (vraR) [Streptomyces sp. 11-1-2]
ATGCCGGGCAATCCGAGTGGCCCCATCAGGGTCCTGCTGGCCGATGACCATCCCGTGGTGCGGGAGGGGCTGAGCGCCAT
GCTGGAGTCCGCCGAGGGGATCACGGTGGTCGGGCAGGCCGGTTCCGGTGAGGAGGCGGTGGTCCAGGCGGTCGCGCTGC
GGCCGGACATCACCCTGCTGGATCTGCGCATGGGCGGGATGGACGGGGTCGAGGCCACCGGGCAGATCCTGCGGCAGGTG
CCGGGCTGCAAGGTGGTCATCGTGACCACGTACGAGGACGACTCCGACATCCTGCGCGCGGTGGAGGCGGGCGCCGCGGG
CTATCTGCTGAAGGGCAGTTCACGCCAGGAGCTGATCGACGCGGTGCAGACCGCGGCGCGTGGCGAAACGGTGCTCACCC
CGTCGCTGGCGGGCAAGCTCTTCCGCTCCCGGACGGTCGAGCCGTCCCCGCTCTCCGGCCGTGAGCGCGAGGTGCTGCGG
CTGGTCGGCCGGGGGCTGACCAACGCCGAGATCGGCGCCGAGCTGTTCGTCAGCGAGGCGACGGTCAAGACGCATCTGCT
CCGGTCGTTCAAGAAGCTCGGCGTCTCCGACCGCACGGCCGCGGTGATGAAGGCGATGGAGCGCGGGTTCTTGAGCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(150-205)

Response regulator receiver domain (Response_reg)

(11-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.291

97.17

0.392

Multiple sequence alignment