Detailed information    

insolico Bioinformatically predicted

Overview

Name   sxy/tfoX   Type   Regulator
Locus tag   AU473_RS21355 Genome accession   NZ_CP017669
Coordinates   4047949..4048578 (-) Length   209 a.a.
NCBI ID   WP_000839159.1    Uniprot ID   A0AAV3HCB2
Organism   Escherichia coli O157:H7 strain PA20     
Function   positive regulator of competence gene (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 4036871..4059752 4047949..4048578 within 0


Gene organization within MGE regions


Location: 4036871..4059752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AU473_RS21290 (AU473_21330) - 4036871..4037890 (+) 1020 WP_001299351.1 tyrosine-type recombinase/integrase -
  AU473_RS21295 (AU473_21335) yccA 4038298..4038957 (+) 660 WP_000375128.1 FtsH protease modulator YccA -
  AU473_RS21300 (AU473_21340) tusE 4039048..4039377 (+) 330 WP_000904442.1 sulfurtransferase TusE -
  AU473_RS21305 (AU473_21345) yccX 4039374..4039652 (-) 279 WP_000048252.1 acylphosphatase -
  AU473_RS21310 (AU473_21350) rlmI 4039747..4040937 (+) 1191 WP_000116288.1 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI -
  AU473_RS21315 (AU473_21355) hspQ 4040995..4041312 (+) 318 WP_001295356.1 heat shock protein HspQ -
  AU473_RS21320 (AU473_21360) yccU 4041357..4041770 (-) 414 WP_000665217.1 CoA-binding protein -
  AU473_RS21330 (AU473_21370) csgI 4041943..4042605 (+) 663 WP_000847791.1 DUF2057 family protein -
  AU473_RS21335 (AU473_21375) mgsA 4042701..4043159 (+) 459 WP_000424181.1 methylglyoxal synthase -
  AU473_RS21340 (AU473_21380) helD 4043191..4045245 (-) 2055 WP_001301436.1 DNA helicase IV -
  AU473_RS21345 (AU473_21385) yccF 4045368..4045814 (+) 447 WP_001261230.1 YccF domain-containing protein -
  AU473_RS21350 (AU473_21390) yccS 4045824..4047986 (+) 2163 WP_000875023.1 YccS family putative transporter -
  AU473_RS21355 (AU473_21395) sxy/tfoX 4047949..4048578 (-) 630 WP_000839159.1 CRP-S regulon transcriptional coactivator Sxy Regulator
  AU473_RS21360 (AU473_21400) sulA 4048797..4049306 (+) 510 WP_000288710.1 SOS-induced cell division inhibitor SulA -
  AU473_RS21370 (AU473_21410) ompA 4049663..4050703 (+) 1041 WP_000750416.1 porin OmpA -
  AU473_RS21375 (AU473_21415) matP 4050779..4051231 (-) 453 WP_000877161.1 macrodomain Ter protein MatP -
  AU473_RS21380 (AU473_21420) ycbZ 4051417..4053177 (+) 1761 WP_000156526.1 AAA family ATPase -
  AU473_RS21385 (AU473_21425) fabA 4053246..4053764 (+) 519 WP_000227927.1 bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase -
  AU473_RS21390 (AU473_21430) rmf 4053834..4054001 (-) 168 WP_000828648.1 ribosome modulation factor -
  AU473_RS21395 (AU473_21435) pqiC 4054257..4054820 (-) 564 WP_000759107.1 membrane integrity-associated transporter subunit PqiC -
  AU473_RS21400 (AU473_21440) pqiB 4054817..4056457 (-) 1641 WP_000445550.1 intermembrane transport protein PqiB -
  AU473_RS21405 (AU473_21445) pqiA 4056462..4057715 (-) 1254 WP_000333170.1 membrane integrity-associated transporter subunit PqiA -
  AU473_RS21410 (AU473_21450) uup 4057845..4059752 (-) 1908 WP_000053083.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 24173.05 Da        Isoelectric Point: 9.1942

>NTDB_id=201427 AU473_RS21355 WP_000839159.1 4047949..4048578(-) (sxy/tfoX) [Escherichia coli O157:H7 strain PA20]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKYPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=201427 AU473_RS21355 WP_000839159.1 4047949..4048578(-) (sxy/tfoX) [Escherichia coli O157:H7 strain PA20]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAATATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA

Domains

Predicted by InterproScan.

TfoX N-terminal domain (TfoX_N)

(14-106)

TfoX C-terminal domain (TfoX_C)

(116-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sxy/tfoX Escherichia coli BW25113 strain K-12

99.522

100

0.995

Multiple sequence alignment