Detailed information NTG0201324

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: BKM66_RS09250
• Genome accession: NZ_CP017666
• Coordinates: 1917205..1919655 (-)
• Length: 816 a.a.
• NCBI ID: WP_105183639.1
• Uniprot ID: A0AAD0P951
• Organism: Streptococcus suis strain 0061
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1912205..1924655

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BKM66_RS09225 (BKM66_08990)	hslO	1914033..1914899 (+)	867	WP_105183636.1	Hsp33 family molecular chaperone HslO	-
BKM66_RS09230 (BKM66_08995)	dusB	1914892..1915896 (+)	1005	WP_105183637.1	tRNA dihydrouridine synthase DusB	-
BKM66_RS09235 (BKM66_09000)	-	1916010..1916489 (-)	480	WP_105183638.1	adenylyltransferase/cytidyltransferase family protein	-
BKM66_RS09240 (BKM66_09005)	-	1916538..1917035 (-)	498	WP_202853269.1	GNAT family N-acetyltransferase	-
BKM66_RS09250 (BKM66_09010)	clpC	1917205..1919655 (-)	2451	WP_105183639.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
BKM66_RS09255 (BKM66_09015)	-	1919659..1920117 (-)	459	WP_002937810.1	CtsR family transcriptional regulator	-
BKM66_RS09260 (BKM66_09020)	-	1920385..1920723 (+)	339	WP_105183640.1	thioredoxin domain-containing protein	-
BKM66_RS09265 (BKM66_09025)	-	1920723..1921424 (+)	702	WP_105183641.1	GNAT family acetyltransferase	-
BKM66_RS09270 (BKM66_09035)	tsf	1921894..1922934 (-)	1041	WP_024407282.1	translation elongation factor Ts	-
BKM66_RS09275 (BKM66_09040)	rpsB	1923202..1923978 (-)	777	WP_012775356.1	30S ribosomal protein S2	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90458.01 Da
• Isoelectric Point: 6.1687

>NTDB_id=201324 BKM66_RS09250 WP_105183639.1 1917205..1919655(-) (clpC) [Streptococcus suis strain 0061]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFVVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSTASQILDKVGFYFEDSDDKFRFLDLRKNLEARAGFTKEDLK
AIRSVMKGGKAKPTNMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQVAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMIKPLLAVTAEKGINLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLATGST
LKVGVKGEELKFDIVI

Nucleotide

• Length: 2451 bp

>NTDB_id=201324 BKM66_RS09250 WP_105183639.1 1917205..1919655(-) (clpC) [Streptococcus suis strain 0061]
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATGCCCAGTTAGTGGCCCAACGTTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCCGGCGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTGTTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACGGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
GCATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTATTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGACTTGCGTAAAAACTTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTACTAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACAAAGAACAACCCAGTTCTGGTTGGTGATGCAGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATTATCA
ACGACATCGAGGAAGATGGTCAGGTCATCCTCTTCATCGATGAGTTGCATACCATTATGGGTTCTGGCTCGGGGATTGAT
TCGACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACAGTCGGAGCGACGACTCAGAC
AGAGTACCAAAAGCATATTGAGAAAGACGCAGCCCTGGTTCGTCGTTTTGCCAAGGTGACCATTGAAGAGCCGACAGTGG
AAGATAGCATTGCCATTTTGACTGGTTTAAAAGGTACTTTTGAGAAATACCACAGGGTCCGTATTGGACAAGTGGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTGCCAGATTCAGCCATTGATTTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGACTGACGAGTATTGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTATCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGTCAGGAAGAAGCTATTTCTGCAGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTCGGTAAG
ACAGAGCTTGCTAAGGCCTTGGCAGAAGTTCTCTTTGATGACGAATCTGCTCTTATCCGTTTTGATATGTCTGAATACAT
GGAGAAATTCGCAGCCAGCCGTTTAAACGGTGCCCCTCCGGGCTATGTGGGCTATGAGGAAGGTGGCGAATTGACAGAAA
AAGTTCGTAACAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTTTTG
CAGGTCTTGGATGATGGTGTTCTGACAGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACCATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTATCTAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAATCGTATTGACGAGAAAGTTGTCTTC
CATAGCCTAACGGAAACTCATATGCAGGATGTTGTCAAGGTCATGATTAAACCTTTGTTGGCTGTAACAGCTGAGAAAGG
AATTAACCTTAAACTGCAACCGTCAGCCCTTAAGTTATTGGCTAAACAAGGTTACGACCCAGAAATGGGGGCTCGTCCAC
TTCGTAGACTCTTACAAACCAAATTAGAAGATCCGTTAGCAGAAATGTTGCTCCGTGGTGACTTGGCTACTGGCTCGACC
TTGAAGGTTGGGGTCAAGGGCGAAGAACTCAAGTTTGATATCGTCATTTAG

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• AAA lid domain (AAA_lid_9) (372-457)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-130)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-56)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	72.025	99.877	0.719
clpC	Streptococcus pneumoniae D39	72.025	99.877	0.719
clpC	Streptococcus pneumoniae TIGR4	72.025	99.877	0.719
clpC	Streptococcus mutans UA159	66.708	99.755	0.665
clpC	Streptococcus thermophilus LMD-9	63.723	100	0.654
clpC	Streptococcus thermophilus LMG 18311	64.14	100	0.653
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.987	100	0.504
clpC	Bacillus subtilis subsp. subtilis str. 168	43.353	100	0.444