Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   BKM66_RS02205 Genome accession   NZ_CP017666
Coordinates   443336..445330 (+) Length   664 a.a.
NCBI ID   WP_105183768.1    Uniprot ID   A0AAD0KV66
Organism   Streptococcus suis strain 0061     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 438336..450330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM66_RS02190 (BKM66_02160) fmt 440323..441261 (+) 939 WP_105183770.1 methionyl-tRNA formyltransferase -
  BKM66_RS02195 (BKM66_02165) rsmB 441248..442561 (+) 1314 WP_105183769.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  BKM66_RS02200 (BKM66_02170) - 442599..443336 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BKM66_RS02205 (BKM66_02175) stkP 443336..445330 (+) 1995 WP_105183768.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  BKM66_RS02210 (BKM66_02180) liaF 445618..446313 (+) 696 WP_024384079.1 cell wall-active antibiotics response protein LiaF -
  BKM66_RS02215 (BKM66_02185) - 446310..447326 (+) 1017 WP_024388026.1 sensor histidine kinase -
  BKM66_RS02220 (BKM66_02190) - 447298..447939 (+) 642 WP_105183767.1 response regulator transcription factor -
  BKM66_RS02225 (BKM66_02195) - 447989..449389 (+) 1401 WP_032510942.1 Cof-type HAD-IIB family hydrolase -
  BKM66_RS02230 (BKM66_02200) - 449391..449762 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71443.91 Da        Isoelectric Point: 6.0714

>NTDB_id=201293 BKM66_RS02205 WP_105183768.1 443336..445330(+) (stkP) [Streptococcus suis strain 0061]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKLPHTNSSAQTSATD
KGSGKKEVAKSGNKPVSKPRSGMRTRYKVLIGAILLTVIAAGLIFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAAMVSIPDVTDKDSDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKEAKITLYVSKGVAPQVVPNVVGKTQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELTKG
SIINLVVSKGKELIMPDLTSGNYTYSQARSQLQALGVNVESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STGTSSDSSTGSSTSTSTSTDSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=201293 BKM66_RS02205 WP_105183768.1 443336..445330(+) (stkP) [Streptococcus suis strain 0061]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCCGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGC
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCTACCATTCAAAGTGACATTTATGCGATGGGAATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGATAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCTTTAGAAAATGTTGTACTAAAAGCAACGGCTAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTACGC
AGATTTAGCTTCGGCCCTATCCATGGATCGTCGGAATGAACCTAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCAAAACTCTCCCAGGCCAATGTAGAAACGAAACTACCGCATACAAACAGTTCTGCCCAAACTTCTGCGACGGAT
AAGGGGTCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGTCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGGGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATATTTTTCAACACTCCACGAACAGTTACCG
TTCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAACATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGAAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGATGGTATCTATTCCAGATGTGACAGATAAGGATTCTGATACTGCACGGC
AGGAATTGGAGGCTCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGTCTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGAGGCGAAAATTACCCTTTACGTTTCCAAAGGAGTAGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAACTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGTATTGGAACTATTA
CTCAGGAATATAGCTCATCTGTTACTGCGGGTCAGGTTATCAGTACAGATCCCGTTGCCAATACAGAGTTGACAAAAGGT
TCTATCATCAATCTAGTTGTTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACTTACTCACA
GGCACGTAGTCAATTACAAGCACTGGGTGTCAATGTGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGCGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCGGCACCAGTAGCGATTCCTCAACAGGAAGTTCCACTAGCACAAGTACTTCAACAGATAGCGGACAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-240)

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(440-501)

PASTA domain (PASTA)

(574-638)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

53.549

97.59

0.523
  stkP Streptococcus pneumoniae D39

53.395

97.59

0.521
  stkP Streptococcus pneumoniae R6

53.395

97.59

0.521
  stkP Streptococcus pneumoniae Rx1

53.241

97.59

0.52
  stkP/pknB Streptococcus salivarius strain HSISS4

52.479

88.102

0.462
  pknB Streptococcus mutans UA159

55.327

80.572

0.446

Multiple sequence alignment