Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CGZ78_RS05980 Genome accession   NZ_CP022440
Coordinates   1154527..1155192 (-) Length   221 a.a.
NCBI ID   WP_002853205.1    Uniprot ID   Q0P933
Organism   Campylobacter jejuni strain 81-176_G1_B0     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1149527..1160192
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGZ78_RS05965 (CGZ78_05970) groES 1151382..1151642 (+) 261 WP_002825273.1 co-chaperone GroES -
  CGZ78_RS05970 (CGZ78_05975) groL 1151664..1153301 (+) 1638 WP_002858047.1 chaperonin GroEL -
  CGZ78_RS05975 (CGZ78_05980) dccS 1153344..1154534 (-) 1191 WP_002868856.1 two-component system sensor histidine kinase DccS -
  CGZ78_RS05980 (CGZ78_05985) ciaR 1154527..1155192 (-) 666 WP_002853205.1 two-component system response regulator DccR Regulator
  CGZ78_RS05985 (CGZ78_05990) - 1155340..1155939 (+) 600 WP_002855731.1 bacteriohemerythrin -
  CGZ78_RS05990 (CGZ78_05995) - 1155950..1156198 (+) 249 WP_002853192.1 ribbon-helix-helix domain-containing protein -
  CGZ78_RS06000 (CGZ78_06005) - 1156456..1157703 (-) 1248 WP_002853241.1 ArsS family sensor histidine kinase -
  CGZ78_RS06005 (CGZ78_06010) - 1157700..1158374 (-) 675 WP_002853196.1 response regulator transcription factor -
  CGZ78_RS06010 (CGZ78_06015) htrA 1158450..1159868 (-) 1419 WP_002868854.1 serine protease HtrA -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25633.32 Da        Isoelectric Point: 4.6834

>NTDB_id=200821 CGZ78_RS05980 WP_002853205.1 1154527..1155192(-) (ciaR) [Campylobacter jejuni strain 81-176_G1_B0]
MAAKILLLEDDLSLSEIIEEFLNDEGYEVFLCDNAQEALDMAYERYFDLWILDVKVPLGDGFSLLKELRKSGKQTPAIFM
TSLNTTNDLKQGFDAGCDDYIKKPFELAELSIRVKALLKRAFSHKNEDFEDLGDGFRFEFTTQILYHNNKALTLPSKEIK
LLSLLLKNKNNFLSTERIFEELWDYDEEPSELSLRAYVKNLRKILGKEKIINQRGRGYCYG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=200821 CGZ78_RS05980 WP_002853205.1 1154527..1155192(-) (ciaR) [Campylobacter jejuni strain 81-176_G1_B0]
ATGGCTGCTAAAATTTTACTTTTAGAAGATGATTTGAGCTTGAGTGAGATCATTGAAGAGTTTTTAAACGATGAGGGATA
TGAAGTATTTTTATGCGATAATGCGCAAGAAGCTTTAGATATGGCTTATGAAAGATATTTTGATCTTTGGATTTTAGATG
TAAAAGTTCCTTTAGGAGATGGATTTTCATTACTTAAAGAATTAAGAAAAAGCGGAAAGCAAACTCCAGCAATTTTCATG
ACTTCTTTAAACACAACAAACGATTTAAAACAAGGCTTTGACGCAGGTTGTGATGATTATATAAAAAAACCTTTTGAACT
TGCCGAGTTATCTATCAGGGTTAAAGCTTTGCTTAAAAGAGCTTTTTCACATAAAAATGAAGATTTTGAAGATTTAGGAG
ATGGATTTAGATTTGAATTTACTACACAAATTCTTTACCATAATAATAAAGCCTTGACTTTACCGAGTAAAGAAATTAAG
CTTTTGTCTTTATTACTTAAAAATAAAAACAACTTTTTAAGTACAGAGAGAATTTTTGAAGAACTCTGGGATTATGATGA
GGAGCCTAGTGAGCTAAGTTTAAGGGCTTATGTGAAAAATTTACGTAAAATTTTAGGAAAAGAAAAAATTATAAATCAAA
GAGGCAGGGGATATTGCTATGGCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q0P933

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae D39

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae R6

36.364

99.548

0.362
  ciaR Streptococcus pneumoniae TIGR4

36.364

99.548

0.362

Multiple sequence alignment