Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   CGZ53_RS09120 Genome accession   NZ_CP022435
Coordinates   1797070..1799613 (-) Length   847 a.a.
NCBI ID   WP_015912076.1    Uniprot ID   B9DW73
Organism   Streptococcus uberis strain NZ01     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1792070..1804613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGZ53_RS09105 (CGZ53_09100) hexB 1793184..1795166 (-) 1983 WP_046388867.1 DNA mismatch repair endonuclease MutL Machinery gene
  CGZ53_RS09110 (CGZ53_09105) - 1795384..1795893 (+) 510 WP_015912074.1 hypothetical protein -
  CGZ53_RS09115 (CGZ53_09110) - 1796120..1796980 (+) 861 WP_015912075.1 staphylokinase domain-containing protein -
  CGZ53_RS09120 (CGZ53_09115) hexA 1797070..1799613 (-) 2544 WP_015912076.1 DNA mismatch repair protein MutS Machinery gene
  CGZ53_RS09125 (CGZ53_09120) - 1799600..1799953 (-) 354 WP_037593101.1 YlbF family regulator -
  CGZ53_RS09130 (CGZ53_09125) argR 1799950..1800387 (-) 438 WP_015912078.1 arginine repressor -
  CGZ53_RS09135 (CGZ53_09130) argS 1800672..1802360 (+) 1689 WP_046389743.1 arginine--tRNA ligase -
  CGZ53_RS09140 (CGZ53_09135) - 1802405..1803283 (-) 879 WP_100912308.1 YitT family protein -
  CGZ53_RS09145 (CGZ53_09140) - 1803330..1804214 (-) 885 WP_037593097.1 YitT family protein -

Sequence

Protein


Download         Length: 847 a.a.        Molecular weight: 95398.04 Da        Isoelectric Point: 5.3848

>NTDB_id=200744 CGZ53_RS09120 WP_015912076.1 1797070..1799613(-) (hexA) [Streptococcus uberis strain NZ01]
MADSKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDILI
ELGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSAKPNSSNNFLIAIDFDGSHYGLSYMDLVTGEFFATTLSDFMS
VCGEILNLKAKEVVIGFEITAEQEEQLQKQFRLLLSYEQEIYTDDTLINPNLSQVEKNVAGKLLQYVHQTQMRELSHLQE
LIHYDIKDYLQMSYATKSSLDLIENARTKKKHGSLYWLLDETKTAMGMRLLKTWIDRPLISKQAISERQNIVETFLESFI
ERSDLADSLKGVYDIERLSSRVSFGKVNPKDLLQLGHTLSQVPYIKAVLEAINSPHLSKVIATIDPIPELESLIHSAIDP
DAPATISEGSIIKTGFDQRLDHYRKVMKEGTGWIADIEMKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESAQLEYDIFMRIREKVETYIDRLQTLAKAIATVDVLQGLAYVAEKNHYVRPEFA
SQKVITIQNGRHAVVEKVMGVQEYIPNTIQFNQNTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAADYAKLPIFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIQRASHDSLIIFDELGRGTATYDGMALAQSIIEHIHNRIGAITLFATHYHEL
TSLSEELGHLKNVHVAILERDGEVTFLHKIAEGPADKSYGIHVAKIAGLPGSLLSRADNILKQLESHSKDFIIKDNSQQS
EENEPLNLLTEETSSQDIINRLKEVDVMNMTPMEAMTVLFDLKKKIK

Nucleotide


Download         Length: 2544 bp        

>NTDB_id=200744 CGZ53_RS09120 WP_015912076.1 1797070..1799613(-) (hexA) [Streptococcus uberis strain NZ01]
ATGGCAGATTCTAAAATTTCTCCTGGAATGCAACAGTATCTGGATATAAAAGCTCAATATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGATTTTTATGAATTGTTTTATGATGATGCTGTAAAAGCTGCACAACTATTAGAAATTGGCTTAACGAGTC
GCAATAAGAATGCGGAAAATCCAATACCGATGGCAGGTGTCCCTCATCACTCTGCTCAGCAATATATTGATATTCTCATT
GAATTAGGCTATAAGGTTGCTATTGCAGAACAAATGGAAGATCCAAAGAAAGCTGTTGGGGTTGTTAAGCGTGAGGTAGT
TCAAGTAATCACGCCTGGTACAGTTGTCGATTCAGCTAAGCCAAATAGTTCCAATAATTTTTTGATTGCAATAGATTTTG
ACGGCAGTCACTATGGATTATCCTACATGGATTTGGTAACGGGAGAATTTTTTGCGACTACCTTGAGTGATTTTATGAGT
GTTTGCGGTGAAATCTTGAATTTAAAAGCAAAAGAAGTGGTTATTGGTTTTGAAATCACTGCTGAACAAGAAGAACAATT
ACAAAAACAGTTTCGTTTATTGCTATCTTATGAGCAAGAAATTTACACAGATGACACTCTCATTAATCCTAATCTATCAC
AAGTGGAAAAGAATGTTGCAGGAAAATTATTACAGTATGTGCATCAGACGCAAATGCGCGAGTTATCCCACCTTCAAGAA
CTCATACACTATGATATCAAGGATTATTTACAAATGTCATATGCGACTAAGTCAAGTCTTGATTTAATTGAGAATGCCAG
AACGAAGAAGAAACATGGAAGTCTCTATTGGCTACTTGACGAAACAAAGACAGCAATGGGGATGCGACTGTTAAAGACAT
GGATTGACAGACCGTTGATTTCAAAGCAAGCTATTAGTGAGCGTCAAAACATTGTAGAAACTTTTTTAGAGTCATTTATT
GAAAGGTCTGATTTAGCAGACAGTCTAAAAGGTGTCTACGATATTGAAAGGTTGTCTAGTCGAGTTTCCTTTGGCAAAGT
TAATCCAAAAGATCTTTTACAACTAGGCCATACTCTAAGTCAAGTACCTTATATTAAAGCTGTATTGGAAGCTATCAACA
GTCCGCATTTATCTAAAGTAATTGCAACCATCGATCCGATACCAGAACTAGAAAGTTTGATTCATTCAGCTATTGACCCA
GACGCACCAGCTACCATTAGTGAAGGCAGTATTATTAAAACTGGTTTTGATCAGCGCTTGGACCATTACCGAAAAGTGAT
GAAAGAAGGCACGGGTTGGATTGCTGATATTGAAATGAAAGAGCGTCAAGCCAGTGGCATCAATAACCTTAAAATTGATT
ACAATAAAAAAGATGGTTACTACTTTCATGTCACAAACTCCAACCTTTCCTTAGTCCCTGACCATTTTTTTAGAAAAGCT
ACGCTAAAAAATTCAGAACGATATGGCACAGCAGAATTAGCTAAAATAGAAGGTCAGATGCTTGAAGCGCGTGAAGAATC
AGCTCAATTAGAATATGATATCTTCATGCGAATCAGAGAGAAAGTGGAAACCTACATTGACAGATTACAGACTTTAGCTA
AAGCAATAGCTACAGTAGATGTATTACAAGGTTTAGCCTATGTTGCTGAGAAAAATCATTATGTCAGACCAGAATTTGCC
TCTCAAAAAGTCATTACGATTCAAAATGGAAGACATGCCGTTGTCGAAAAGGTCATGGGAGTTCAAGAGTACATTCCAAA
TACTATCCAATTTAATCAAAATACGTCTATCCAATTGATAACTGGCCCAAATATGAGTGGGAAATCGACTTATATGAGAC
AATTGGCTTTAACTGTTATCATGGCTCAAATGGGATCTTATGTAGCAGCTGACTACGCCAAATTACCAATCTTTGATGCT
ATCTTTACGCGTATTGGAGCAGCAGATGACTTAATATCTGGCCAATCAACATTTATGGTTGAAATGATGGAAGCTAACCA
AGCAATTCAAAGAGCTAGTCACGATAGTCTCATCATCTTTGATGAACTTGGACGTGGAACAGCCACTTATGATGGTATGG
CCCTGGCACAGTCCATCATCGAACATATTCATAACAGAATAGGAGCCATTACTCTTTTTGCTACCCACTATCATGAGTTG
ACTTCCTTGTCGGAAGAACTTGGGCACCTCAAGAATGTTCATGTAGCTATTTTAGAAAGAGATGGTGAAGTAACCTTTCT
TCATAAAATTGCGGAAGGCCCAGCCGATAAATCATATGGTATCCATGTGGCAAAAATTGCAGGCTTACCAGGCTCTTTGC
TGAGCCGAGCAGATAATATTTTAAAACAGTTGGAAAGCCATTCCAAGGATTTTATCATAAAAGATAATTCGCAACAATCA
GAAGAAAATGAGCCATTAAATTTATTGACGGAGGAGACTTCCTCTCAAGATATCATTAATAGACTTAAAGAAGTAGATGT
CATGAATATGACTCCAATGGAAGCTATGACTGTTTTGTTTGATCTAAAGAAAAAAATAAAATAA

Domains

Predicted by InterProScan.

MutS domain I (MutS_I)

(8-118)

MutS family domain IV (MutS_IV)

(415-506)

MutS domain II (MutS_II)

(126-239)

MutS domain V (MutS_V)

(599-785)

MutS domain III (MutS_III)

(256-546)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DW73

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

69.976

99.882

0.699
  mutS Pseudomonas stutzeri strain ATCC 17587

36.279

100

0.368