Detailed information NTG0020058

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SDD27957_10635
• Genome accession: CM001076
• Coordinates: 2018621..2021065 (-)
• Length: 814 a.a.
• NCBI ID: EFY03710.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2013621..2026065

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SDD27957_10615	-	2013977..2015473 (+)	1497	EFY03706.1	dipeptidase	-
SDD27957_10620	-	2015807..2016274 (+)	468	EFY03707.1	MutT/nudix family protein	-
SDD27957_10625	groEL	2016492..2018117 (-)	1626	EFY03708.1	chaperonin GroEL	-
SDD27957_10630	groES	2018153..2018443 (-)	291	EFY03709.1	co-chaperonin GroES	-
SDD27957_10635	clpC	2018621..2021065 (-)	2445	EFY03710.1	negative regulator of genetic competence clpC/mecB	Regulator
SDD27957_10640	-	2021065..2021526 (-)	462	EFY03711.1	Putative transcriptional regulator	-
SDD27957_10645	-	2021723..2021926 (-)	204	EFY03712.1	Major cold-shock protein	-
SDD27957_10650	-	2022334..2022510 (+)	177	EFY03713.1	hypothetical protein	-
SDD27957_10655	-	2022511..2022753 (+)	243	EFY03714.1	hypothetical protein	-
SDD27957_10660	-	2022900..2023211 (+)	312	EFY03715.1	putative hydratase	-
SDD27957_10665	-	2023342..2023797 (+)	456	EFY03716.1	MarR family regulatory protein	-
SDD27957_10670	-	2023784..2025175 (+)	1392	EFY03717.1	2-keto-3-deoxygluconate permease	-
SDD27957_10675	-	2025291..2025569 (+)	279	EFY03718.1	acetyltransferase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90356.07 Da
• Isoelectric Point: 6.7392

>NTDB_id=20058 SDD27957_10635 EFY03710.1 2018621..2021065(-) (clpC) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
MIMYSLKMQEIFRQAQFQAARFDSQYLETWHILLAMARVDHSLAGLVLSEFDAKVAVEEYEAAAILAMGKSPKDQVSHID
FRPQSKTLTNLLQFAQAISHVTKDQEVGSEHVLFAILLNPDIMATRLLEMAGYAIKDKGNGEPRLADLRKAIEIHAGYSK
EMIKAIHELRKPKKTKNQGSFSDMMKPPSTAGDLADFTRDLTEMASQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNVEDAYQILIGLKGSYETYHNVTIAD
QAVRTAVKMAHRYLTSKNLPDSAIDLLDEASATVQGMVKKTSPEIITPLDQALIDGDMKKASRLLAKDVKGQHRKPTAVT
EEDILTTLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQKDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNILLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGISHDHQAMEKRILEELKKTYRPEFINRIDEKVVFR
SLTQDNMREVVKIMVQPMMATLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGELASGHTL
KIGLSHGKLSFNIE

Nucleotide

• Length: 2445 bp

>NTDB_id=20058 SDD27957_10635 EFY03710.1 2018621..2021065(-) (clpC) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
ATGATCATGTATTCATTGAAGATGCAAGAAATTTTCAGGCAGGCGCAATTTCAAGCAGCCCGCTTTGATAGCCAATACCT
AGAAACTTGGCATATATTGCTAGCTATGGCGAGGGTTGATCACTCCCTAGCGGGTTTGGTGCTAAGCGAATTTGATGCTA
AGGTTGCAGTGGAAGAATATGAGGCTGCAGCTATTTTAGCTATGGGCAAAAGCCCTAAAGACCAAGTGTCTCACATTGAC
TTTAGGCCTCAGTCAAAAACCTTAACGAACCTTTTGCAATTTGCCCAAGCTATCAGTCATGTCACCAAAGACCAAGAGGT
AGGTTCAGAGCATGTTCTCTTTGCCATTTTGCTTAATCCAGATATTATGGCGACTCGCTTATTAGAGATGGCTGGTTATG
CTATCAAGGATAAAGGAAACGGAGAACCTCGCTTAGCTGATTTACGAAAAGCTATCGAGATTCATGCAGGCTATAGTAAG
GAAATGATTAAGGCTATCCACGAGTTGCGTAAACCAAAGAAAACCAAGAATCAAGGTTCTTTTTCAGACATGATGAAGCC
ACCAAGCACGGCTGGGGATTTGGCGGACTTTACACGTGATTTGACCGAGATGGCAAGCCAAGGTCTCTTAGAGCCAGTTA
TTGGCCGTGATGCTGAAGTATCACGGATGATCCAAGTACTGAGTCGTAAAACCAAGAATAACCCTGTTCTTGTGGGTGAT
GCAGGTGTGGGTAAAACGGCCCTTGCCTATGGTCTTGCCCAACGTATTGCTAATGGTGCTATTCCTTATGAACTGCAAGA
CATGCGTGTTCTAGAATTAGATATGATGAGTGTTGTTGCGGGGACCCGTTTTCGTGGGGATTTTGAAGAACGCATGAATC
AAATCATTGACGATATTGAGTCAGATGGCAAGATTATTCTCTTCGTAGATGAATTGCACACCATTATGGGATCAGGAAGT
GGTATTGATAGCACACTTGATGCTGCCAATATTTTAAAACCAGCCTTATCTCGCGGAACCCTCCATATGGTGGGTGCAAC
AACGCAGGAAGAATACCAAAAACACATTGAAAAAGATGCCGCTCTTTCGCGTCGCTTTGCTAAGATTTTAATTGAAGAGC
CTAATGTAGAAGATGCTTATCAGATTCTGATCGGGTTAAAAGGCTCTTACGAGACTTACCATAATGTGACCATTGCTGAT
CAGGCTGTTAGAACTGCTGTGAAAATGGCACATCGCTATCTGACCAGCAAAAACCTTCCAGATTCTGCCATTGATTTGCT
AGATGAAGCTAGTGCCACTGTCCAAGGTATGGTTAAAAAAACCAGTCCAGAAATCATCACGCCATTAGATCAAGCTTTGA
TTGATGGCGATATGAAGAAGGCCTCTCGTTTGTTGGCAAAAGACGTTAAAGGACAACATCGTAAGCCAACAGCTGTGACA
GAAGAGGATATCCTGACAACCTTGAGCAAGCTATCAGGTATTCCACTGGAAAAACTCAGCCAAGCTGATAGCAAAAAATA
CCTTAATTTGGAAAAAGAACTGCATAAGCGCGTGATTGGGCAAAAAGATGCTGTCTCAGCTATTTCTCGAGCGATTCGTC
GTAATCAGTCAGGCATCCGTACAGGTAAACGTCCGATTGGTTCCTTCATGTTCCTTGGTCCAACAGGGGTTGGTAAGACT
GAGTTGGCTAAAGCCTTGGCAGAAGTTCTCTTTGACGACGCGTCTGCCCTTATCCGCTTTGATATGTCAGAGTATATGGA
AAAATTTGCGGCTTCTCGTCTTAATGGCGCACCTCCAGGCTATGTCGGTTACGATGAAGGTGGTGAATTAACAGAGAAGG
TCAGAAACAAGCCTTACTCCGTGCTCCTCTTTGACGAGGTGGAAAAAGCTCACCCTGATATTTTCAACATACTCTTACAA
GTGCTTGATGACGGCATGTTGACAGATAGCCGTGGGCGTAAAGTGGACTTCTCAAACACTATTATTATCATGACAAGTAA
TCTAGGGGCAACAGCTCTGCGTGATGATAAAACAGTTGGCTTTGGGGCAAAAGGCATTAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAGAAAACTTACCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCGC
AGCCTCACTCAGGATAATATGAGAGAAGTGGTCAAGATTATGGTGCAGCCGATGATGGCTACTTTGGCAGAAAAAGGCAT
TACCCTTAAATTCCAGCCAATGGCCCTCAAATATTTATCAGAAGAAGGGTACGATGTGGAAATGGGTGCTCGTCCATTGC
GCCGTACTTTGCAAACTCAGGTGGAAGATAAATTGTCTGAATTGATTCTTGCTGGTGAATTGGCAAGTGGTCATACCCTG
AAAATTGGTCTTTCTCATGGAAAACTCAGCTTTAACATTGAGTGA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• AAA lid domain (AAA_lid_9) (376-461)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-133)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.384	99.877	0.763
clpC	Streptococcus thermophilus LMD-9	72.917	100	0.731
clpC	Streptococcus thermophilus LMG 18311	72.672	100	0.729
clpC	Streptococcus pneumoniae TIGR4	66.79	99.877	0.667
clpC	Streptococcus pneumoniae Rx1	66.79	99.877	0.667
clpC	Streptococcus pneumoniae D39	66.79	99.877	0.667
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.561	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	42.96	100	0.439