Detailed information NTG0020045

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: SDD27957_07625
• Genome accession: CM001076
• Coordinates: 1452966..1455257 (+)
• Length: 763 a.a.
• NCBI ID: EFY03143.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1447966..1460257

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SDD27957_07575	-	1447981..1448130 (-)	150	EFY03138.1	hypothetical protein	-
SDD27957_07605	-	1450317..1450691 (-)	375	EFY03139.1	putative ferrous ion transport protein A	-
SDD27957_07610	-	1450889..1451623 (-)	735	EFY03140.1	amino acid ABC transporter ATP-binding protein	-
SDD27957_07615	-	1451623..1452309 (-)	687	EFY03141.1	Putative amino acid ABC transporter	-
SDD27957_07620	-	1452437..1452667 (-)	231	EFY03142.1	hypothetical protein	-
SDD27957_07625	clpE	1452966..1455257 (+)	2292	EFY03143.1	ATP-dependent endopeptidase Clp ATP-binding subunit clpE	Regulator
SDD27957_07630	-	1455375..1455827 (+)	453	EFY03144.1	mutator protein (7,8-dihydro-8-oxoguanine-triphosphatase)	-
SDD27957_07635	-	1455881..1456183 (+)	303	EFY03145.1	hypothetical protein	-
SDD27957_07640	ileS	1456596..1459397 (-)	2802	EFY03146.1	isoleucyl-tRNA synthetase	-

Sequence

Protein

• Length: 763 a.a.
• Molecular weight: 84956.21 Da
• Isoelectric Point: 5.2743

>NTDB_id=20045 SDD27957_07625 EFY03143.1 1452966..1455257(+) (clpE) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
MLCQNCNLNESTIHLYTNVNGKQKQVDLCQNCYQIMKTDPTNPILGGLNGGQRAQERSSNPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRHGGHFNGQRPTQPQTQNQQVKGLLEEFGINVTDIARHGDIDPVIGRDDEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIVDGTVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
IAKYKEMQAQKVDEQDIPIITEKTIEAIIEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKDNLLHIVDLMLEDVNKRLGYNGIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKDLRAIMTSNGNVMIKAAKKDETVTAKQDQTDEN

Nucleotide

• Length: 2292 bp

>NTDB_id=20045 SDD27957_07625 EFY03143.1 1452966..1455257(+) (clpE) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
ATGCTTTGTCAAAATTGTAATTTAAACGAATCAACCATCCACCTCTACACGAATGTTAATGGAAAACAAAAACAAGTTGA
CCTTTGTCAAAACTGTTATCAAATCATGAAGACTGACCCTACTAATCCTATTTTAGGTGGTCTAAATGGAGGTCAAAGAG
CCCAAGAACGCTCATCCAACCCCTTCTTTGATGACTTTTTTGGTGATTTAAATAATTTTAGAGCCTTTGGCAACCTTCCA
AATACCCCGCCTACACAAGCAGGCCAAAATGGCAACGGAGGAGGACGCCATGGTGGTCATTTCAATGGGCAACGTCCCAC
TCAGCCACAAACACAAAATCAGCAAGTAAAGGGCTTGTTAGAAGAATTTGGGATTAATGTTACAGATATTGCAAGACATG
GTGATATTGACCCTGTCATCGGTCGAGATGACGAGATTACACGTGTCATCGAAATCCTTAACCGTCGGACTAAAAATAAC
CCTGTGCTTATTGGGGAACCAGGAGTTGGTAAAACAGCTGTTGTAGAAGGTCTAGCCCAGAAAATTGTAGATGGCACAGT
ACCTCACAAATTGCAAGGTAAGCAAGTGATTCGTCTAGATGTGGTTAGTCTTGTTCAAGGCACAGGTATCCGTGGTCAAT
TCGAAGAACGCATGCAAAAATTAATGGAAGAAATTCGTCAACGCAAAGATGTGATTCTCTTTATTGATGAAATTCATGAA
ATTGTAGGTGCTGGTTCTGCTGGAGATGGCAATATGGATGCTGGCAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACCTTAAATGAATACCGTATTATTGAAAAAGATGCTGCCTTGGAGCGGCGGATGCAGCCGG
TTAAAGTTGACGAACCTTCTGTAGAAGAAACCATTACCATCTTAAAAGGTATCCAGCCCAAATATGAAGACTATCATCAT
GTCAAATATAGCCCAGCAGCTATCGAGGCTGCTGCACACTTATCCAATCGCTACATTCAAGACCGATTCCTCCCTGATAA
GGCCATTGACCTTCTGGACGAAGCTGGTTCAAAAATGAATTTAACCCTTAATTTTGTTGACCCTAAAGAGATTGACAAAC
GTCTGATTGAAGCAGAAAACCTCAAGGCTCAAGCAACTCGTGACGAAGATTACGAACGAGCAGCCTATTTCCGAGATCAA
ATTGCGAAATACAAGGAAATGCAAGCTCAAAAAGTCGACGAACAGGATATTCCTATCATTACTGAAAAAACCATTGAAGC
CATCATTGAACAAAAAACCAATATTCCAGTTGGCGATTTGAAAGAAAAAGAACAATCTCAACTCGTTAATTTGGCTAATG
ATTTGAAAGCTCACGTGATTGGCCAAGATGATGCCGTTGACAAAATTGCCAAGGCCATTCGCCGGAACCGTGTGGGATTA
GGAACTCCAAATCGTCCTATTGGTTCTTTCCTATTCGTTGGGCCAACAGGTGTTGGTAAAACAGAATTGTCTAAGCAACT
AGCTATTGAACTCTTTGGCTCTGCTGACAATATGATTCGCTTTGACATGTCCGAATACATGGAAAAACATGCCGTTGCTA
AATTAGTCGGGGCTCCTCCTGGTTATGTGGGCTATGAAGAAGCTGGCCAGTTAACGGAACAAGTTCGCCGCAATCCATAT
TCACTTATTCTCTTAGATGAAGTGGAAAAGGCTCATCCTGACGTCATGCACATGTTTTTACAAGTTCTTGATGATGGCCG
TTTAACAGATGGTCAAGGACGAACAGTCAGCTTCAAGGATACTATTATTATCATGACCTCTAATGCCGGAACAGGTAAAA
GTGAAGCTTCTGTTGGATTTGGTGCAGCTAGAGAAGGACGAACAAGTTCTGTCCTTGGTGAATTAAGTAACTTCTTCAGC
CCAGAGTTCATGAACCGTTTCGATGGTATTATTGAATTTAAGGCCTTGAGCAAAGATAACCTCTTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATAAGCGCTTAGGCTATAATGGGATTCACCTTGATGTGACGCAAAAAGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGTGCTCGACCGCTCCGTCGTACCATCCAAGATTATATCGAAGATGCGATTACG
GACTACTATTTGGAACATCCAACTGAAAAGGACTTGCGTGCCATAATGACAAGTAACGGTAATGTTATGATTAAAGCTGC
CAAAAAAGATGAAACGGTAACAGCTAAACAAGATCAGACCGACGAGAACTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (162-281)

• AAA lid domain (AAA_lid_9) (300-397)

• AAA domain (Cdc48 subfamily) (AAA_2) (485-648)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (656-730)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.582	99.083	0.848
clpE	Streptococcus pneumoniae Rx1	83.794	99.476	0.834
clpE	Streptococcus pneumoniae D39	83.794	99.476	0.834
clpE	Streptococcus pneumoniae R6	83.794	99.476	0.834
clpE	Streptococcus pneumoniae TIGR4	83.663	99.476	0.832
clpC	Lactococcus lactis subsp. cremoris KW2	76.599	96.33	0.738
clpC	Bacillus subtilis subsp. subtilis str. 168	49.781	89.777	0.447
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.308	85.19	0.394
clpC	Streptococcus pneumoniae Rx1	47.84	81.913	0.392
clpC	Streptococcus pneumoniae D39	47.84	81.913	0.392
clpC	Streptococcus pneumoniae TIGR4	47.84	81.913	0.392
clpC	Streptococcus mutans UA159	47.581	81.258	0.387
clpC	Streptococcus thermophilus LMD-9	46.215	83.093	0.384
clpC	Streptococcus thermophilus LMG 18311	45.899	83.093	0.381