Detailed information    

insolico Bioinformatically predicted

Overview

Name   recP/tkt   Type   Machinery gene
Locus tag   CFN12_RS06870 Genome accession   NZ_CP022290
Coordinates   1333245..1335233 (+) Length   662 a.a.
NCBI ID   WP_000481443.1    Uniprot ID   P66962
Organism   Staphylococcus aureus strain EDCC5458     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1328245..1340233
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFN12_RS06830 (CFN12_06795) rpmG 1328326..1328475 (+) 150 WP_001265708.1 50S ribosomal protein L33 -
  CFN12_RS06835 (CFN12_06800) rpsN 1328929..1329198 (+) 270 WP_001085655.1 30S ribosomal protein S14 -
  CFN12_RS06840 (CFN12_06805) guaC 1329355..1330332 (+) 978 WP_000688126.1 GMP reductase -
  CFN12_RS06850 (CFN12_06815) - 1330354..1331370 (+) 1017 WP_001789887.1 CAP domain-containing protein -
  CFN12_RS06855 (CFN12_06820) dinR/lexA 1331750..1332373 (-) 624 WP_001208760.1 transcriptional repressor LexA Regulator
  CFN12_RS06860 (CFN12_06825) sosA 1332516..1332749 (+) 234 WP_100183649.1 DNA damage-induced cell division inhibitor SosA -
  CFN12_RS06865 (CFN12_06830) - 1332885..1333124 (+) 240 WP_000071351.1 DUF896 domain-containing protein -
  CFN12_RS06870 (CFN12_06835) recP/tkt 1333245..1335233 (+) 1989 WP_000481443.1 transketolase Machinery gene
  CFN12_RS06875 (CFN12_06840) - 1335511..1335753 (+) 243 WP_000246909.1 YneF family protein -
  CFN12_RS06880 (CFN12_06845) - 1335740..1335838 (+) 99 WP_001789897.1 hypothetical protein -
  CFN12_RS06885 (CFN12_06850) - 1335932..1336399 (+) 468 WP_000966142.1 CcdC family protein -
  CFN12_RS06890 (CFN12_06855) sbcD 1336523..1337644 (+) 1122 WP_000691284.1 exonuclease subunit SbcD -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 72250.84 Da        Isoelectric Point: 4.7072

>NTDB_id=200218 CFN12_RS06870 WP_000481443.1 1333245..1335233(+) (recP/tkt) [Staphylococcus aureus strain EDCC5458]
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRDRFVLSAGHGSALLYSLLHVS
GSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQGFAMSVGLALAEDHLAGKFNKEGYNVVDHYTYVLASDGDLM
EGISHEAASFAGHNKLSKLVVLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDKAITTAKSQEGPTI
IEVKTTIGFGSPNKAGTNGVHGAPLGEVERKLTFENYGLDPEKRFNVSEEVYEIFQNTMLKRANEDESQWNSLLEKYAET
YPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSGTVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPE
GKNVWFGVREFAMGAAVNGMAAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGAYTVYGSEETPEFLLLASGSE
VSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESVIPSSVTKRVAIEMASPLGWHKYVGTAGKVIAIDGFGASAP
GDLVVEKYGFTKENILNQVMSL

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=200218 CFN12_RS06870 WP_000481443.1 1333245..1335233(+) (recP/tkt) [Staphylococcus aureus strain EDCC5458]
ATGTTTAATGAAAAAGATCAATTAGCTGTTGATACGCTACGTGCACTAAGTATCGACACAATCGAAAAAGCGAATTCTGG
TCATCCAGGATTACCTATGGGAGCTGCCCCAATGGCTTACACTTTGTGGACACGTCATCTGAATTTTAATCCACAATCTA
AAGATTACTTCAATAGAGACCGTTTCGTATTATCTGCAGGGCATGGTTCAGCATTATTGTATAGCTTGTTACATGTTTCT
GGTAGTTTAGAATTAGAAGAATTAAAGCAATTTAGACAATGGGGTTCTAAAACACCAGGTCATCCTGAATACAGACATAC
AGATGGTGTAGAAGTTACTACCGGACCACTTGGACAAGGTTTTGCTATGTCAGTAGGATTAGCTTTAGCAGAAGATCACC
TAGCAGGGAAATTTAATAAAGAAGGATATAATGTTGTAGATCATTACACATATGTATTAGCTTCTGACGGTGATTTAATG
GAAGGTATATCGCATGAAGCAGCTTCATTTGCTGGACATAATAAATTAAGTAAATTAGTTGTTTTATACGATTCAAATGA
TATTTCATTAGATGGCGAATTAAACAAAGCTTTTTCTGAAAACACAAAAGCTCGTTTTGAAGCATATGGTTGGAATTACT
TACTAGTTAAAGATGGTAATGATTTAGAAGAAATTGATAAAGCGATTACTACAGCTAAATCTCAAGAAGGACCAACGATT
ATTGAAGTTAAAACAACAATCGGATTTGGTTCACCGAATAAAGCAGGAACTAATGGTGTTCATGGGGCACCTTTAGGTGA
AGTTGAAAGAAAATTAACATTCGAAAATTACGGTTTAGATCCTGAAAAACGTTTTAATGTTTCAGAAGAGGTATACGAAA
TTTTCCAAAATACTATGTTAAAACGTGCTAATGAAGATGAATCTCAATGGAATTCATTATTAGAAAAATATGCAGAAACA
TATCCTGAATTAGCAGAAGAATTTAAATTAGCGATTAGTGGTAAATTGCCTAAAAATTATAAGGATGAATTACCACGTTT
TGAACTGGGTCATAATGGTGCATCTCGTGCTGATTCTGGTACTGTTATTCAAGCAATCAGTAAAACTGTCCCTTCATTCT
TTGGTGGATCAGCAGACCTTGCTGGTTCAAACAAATCCAATGTAAATGATGCAACTGATTATAGTTCTGAAACACCTGAA
GGTAAAAATGTGTGGTTTGGTGTACGTGAATTTGCTATGGGTGCTGCTGTAAATGGTATGGCTGCACATGGAGGTTTACA
TCCATATGGTGCAACATTCTTCGTATTTAGTGATTATTTAAAACCAGCGTTACGTTTATCATCAATTATGGGATTAAATG
CAACGTTCATCTTCACACATGATTCAATTGCAGTAGGTGAAGATGGTCCTACTCATGAACCAATTGAGCAATTAGCTGGA
TTAAGAGCCATTCCAAATATGAATGTTATCCGTCCTGCTGATGGTAATGAAACAAGAGTAGCATGGGAAGTTGCCTTAGA
ATCTGAATCTACACCTACTTCATTAGTATTGACACGTCAAAACTTACCGGTATTAGATGTACCAGAAGATGTAGTTGAAG
AAGGCGTTCGAAAAGGTGCCTATACAGTTTATGGCTCTGAAGAGACACCAGAATTCCTATTATTAGCTTCAGGTTCAGAA
GTTAGTCTTGCAGTTGAAGCTGCTAAAGATCTTGAAAAACAAGGTAAATCAGTACGTGTTGTTTCAATGCCTAACTGGAA
TGCATTTGAACAACAATCTGAAGAATATAAAGAATCAGTCATTCCATCAAGCGTAACAAAACGTGTTGCGATTGAAATGG
CTTCACCGCTTGGATGGCATAAATATGTAGGTACTGCAGGTAAAGTTATTGCTATTGACGGCTTTGGCGCAAGTGCACCT
GGCGATTTAGTAGTTGAAAAATATGGATTTACAAAAGAAAATATCTTAAACCAAGTTATGAGCTTATAA

Domains

Predicted by InterProScan.

Transketolase, thiamine diphosphate binding domain (Transketolase_N)

(6-337)

Transketolase, C-terminal domain (Transketolase_C)

(548-655)

Transketolase, pyrimidine binding domain (Transket_pyr)

(359-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66962

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recP/tkt Streptococcus pneumoniae TIGR4

55.105

100

0.554

Multiple sequence alignment