Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   CFA72_RS05930 Genome accession   NZ_CP022206
Coordinates   1114966..1115442 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain GURSA1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1109966..1120442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFA72_RS05915 (CFA72_05915) fbp54 1110779..1112431 (+) 1653 WP_093974729.1 Rqc2 family fibronectin-binding protein Fbp54 -
  CFA72_RS05920 (CFA72_05920) - 1112490..1113737 (-) 1248 WP_030126713.1 tetratricopeptide repeat protein -
  CFA72_RS05925 (CFA72_05925) - 1113727..1114908 (-) 1182 WP_002990002.1 AI-2E family transporter -
  CFA72_RS05930 (CFA72_05930) mutX 1114966..1115442 (-) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  CFA72_RS05935 (CFA72_05935) speh 1116046..1116757 (-) 712 Protein_1099 streptococcal pyrogenic exotoxin SpeH -
  CFA72_RS05940 (CFA72_05940) spei 1116783..1117460 (-) 678 WP_080286815.1 streptococcal pyrogenic exotoxin SpeI -
  CFA72_RS05945 (CFA72_05945) - 1117734..1119068 (-) 1335 WP_015898599.1 GH25 family lysozyme -
  CFA72_RS05950 (CFA72_05950) - 1119180..1119365 (-) 186 WP_011054731.1 holin -
  CFA72_RS05955 (CFA72_05955) - 1119362..1119658 (-) 297 WP_023078532.1 hypothetical protein -
  CFA72_RS05960 (CFA72_05960) - 1119669..1120280 (-) 612 WP_093974731.1 DUF1366 domain-containing protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=199753 CFA72_RS05930 WP_002984880.1 1114966..1115442(-) (mutX) [Streptococcus pyogenes strain GURSA1]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=199753 CFA72_RS05930 WP_002984880.1 1114966..1115442(-) (mutX) [Streptococcus pyogenes strain GURSA1]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703