Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   CFA72_RS04155 Genome accession   NZ_CP022206
Coordinates   760126..761931 (+) Length   601 a.a.
NCBI ID   WP_020837346.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain GURSA1     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 755126..766931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFA72_RS04135 (CFA72_04135) queA 756086..757114 (-) 1029 WP_002995782.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  CFA72_RS04140 (CFA72_04140) nagB 757316..758020 (+) 705 WP_002995779.1 glucosamine-6-phosphate deaminase -
  CFA72_RS04145 (CFA72_04145) - 758139..758855 (+) 717 WP_002995774.1 pseudouridine synthase -
  CFA72_RS04150 (CFA72_04150) coiA 759151..760113 (+) 963 WP_002983995.1 competence protein CoiA Machinery gene
  CFA72_RS04155 (CFA72_04155) pepF 760126..761931 (+) 1806 WP_020837346.1 oligoendopeptidase F Regulator
  CFA72_RS04160 (CFA72_04160) - 762307..763503 (+) 1197 WP_093974674.1 OFA family MFS transporter -
  CFA72_RS04165 (CFA72_04165) - 763569..764276 (+) 708 WP_020837344.1 O-methyltransferase -
  CFA72_RS04170 (CFA72_04170) prsA 764339..765394 (+) 1056 WP_020837342.1 peptidylprolyl isomerase PrsA -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 69309.28 Da        Isoelectric Point: 4.8409

>NTDB_id=199741 CFA72_RS04155 WP_020837346.1 760126..761931(+) (pepF) [Streptococcus pyogenes strain GURSA1]
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKGFAGHLLDSSANLLKVTKTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSIRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=199741 CFA72_RS04155 WP_020837346.1 760126..761931(+) (pepF) [Streptococcus pyogenes strain GURSA1]
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGCACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTCAGTGACTTAGCTACTGAAGTTGAGGCATCTAAAGGTTTTGCTGGTCATTTGCTGGATTCTAGTGCTAATT
TGTTAAAGGTTACAAAAACATATTTAGAATTGGCTCGTCGTGTGGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTGTTTTC
ATTCTATGACCCAGAAGTTATGGCATTGAGTCAGGAAGATTACCAAGCTTTTCTTGCGGAAACACCTGATTTAAAAAGGT
ATCATCATTTCTTTGACAAATTGTTCCAGACACGTGACCATGTGCTCAGCCAGGCTGAAGAGGAATTATTAGCAGGAGCC
CAAGAAATTTTCAACGGCGCTGAAGAAACCTTTAGTATTCTTGATAACGCTGATATTGTCTTTCCAGTAGTTAAAAATGA
TAAGGGGGAAGATGTTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCATTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCACGTCAAGCTGCCATGGCTGCTAACTTTATTCCAGAAGCTGTTTA
CGATACCTTGTTAGAAACGGTTAATAAACATTTGCCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCATTATCTGAAACAGATCTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTGGCTGTTTTTGGTAAAGATTACGCAGATCGTGTGCATCGTGCTTTTACTGAACGTTGGATTGA
TGTTCATGTCAATAAAGGGAAGCGCTCTGGGGCTTATTCAGGTGGTTCCTATGATACCAATGCCTTCATGCTGTTGAATT
GGCAAGATACACTTGATAATCTTTACACACTTGTCCACGAAACAGGCCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGGGATTATAGTATCTTCTTGGCAGAAATTGCATCCACAACGAATGAAAACATCATGACAGAAGC
TCTCTTAAATGAGGTGCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTCATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGGTTTGCAGCTGCAAGCTATTTAGCGG
ATAAGATTGTGCATGGCACACAAGATGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGGCAAAAGGTGATTATTTGGAAGCTGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAGCTAA

Domains

Predicted by InterProScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

71.215

100

0.712