Detailed information
Bioinformatically predicted
Overview
| Name | comGH | Type | Machinery gene |
| Locus tag | CFA72_RS00690 | Genome accession | NZ_CP022206 |
| Coordinates | 105656..106609 (+) | Length | 317 a.a. |
| NCBI ID | WP_023610092.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain GURSA1 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 100656..111609
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CFA72_RS00650 (CFA72_00650) | - | 101468..101833 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| CFA72_RS00655 (CFA72_00655) | comGA | 101926..102879 (+) | 954 | WP_030126921.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| CFA72_RS00660 (CFA72_00660) | comGB | 102815..103849 (+) | 1035 | WP_225793059.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| CFA72_RS00665 (CFA72_00665) | comGC | 103851..104177 (+) | 327 | WP_002986552.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| CFA72_RS00670 (CFA72_00670) | comGD | 104152..104580 (+) | 429 | WP_023605232.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| CFA72_RS00675 (CFA72_00675) | comGE | 104537..104821 (+) | 285 | WP_011284422.1 | competence type IV pilus minor pilin ComGE | Machinery gene |
| CFA72_RS00680 (CFA72_00680) | comGF | 104814..105248 (+) | 435 | WP_002992738.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| CFA72_RS00685 (CFA72_00685) | comGG | 105232..105558 (+) | 327 | WP_002992739.1 | competence type IV pilus minor pilin ComGG | - |
| CFA72_RS00690 (CFA72_00690) | comGH | 105656..106609 (+) | 954 | WP_023610092.1 | class I SAM-dependent methyltransferase | Machinery gene |
| CFA72_RS00695 (CFA72_00695) | - | 106668..107864 (+) | 1197 | WP_002992742.1 | acetate kinase | - |
| CFA72_RS00700 (CFA72_00700) | - | 108051..108359 (+) | 309 | WP_032467031.1 | hypothetical protein | - |
| CFA72_RS00705 (CFA72_00705) | proC | 108442..109212 (-) | 771 | WP_002992745.1 | pyrroline-5-carboxylate reductase | - |
| CFA72_RS00710 (CFA72_00710) | pepA | 109260..110327 (-) | 1068 | WP_002992747.1 | glutamyl aminopeptidase | - |
| CFA72_RS00720 (CFA72_00720) | - | 110792..111076 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| CFA72_RS00725 (CFA72_00725) | - | 111073..111390 (+) | 318 | WP_093974498.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 35969.12 Da Isoelectric Point: 4.7866
>NTDB_id=199700 CFA72_RS00690 WP_023610092.1 105656..106609(+) (comGH) [Streptococcus pyogenes strain GURSA1]
MTFEKIEEAYQLLLENCQLIENVLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENVLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=199700 CFA72_RS00690 WP_023610092.1 105656..106609(+) (comGH) [Streptococcus pyogenes strain GURSA1]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGTTCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCTTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAAATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACACTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGTTCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCTTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAAATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACACTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGH | Streptococcus mutans UA159 |
66.139 |
99.685 |
0.659 |
| comGH | Streptococcus mutans UA140 |
65.823 |
99.685 |
0.656 |