Detailed information NTG0198514

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BJG87_RS04505
• Genome accession: NZ_CP017463
• Coordinates: 930677..931720 (+)
• Length: 347 a.a.
• NCBI ID: WP_017637854.1
• Uniprot ID: A0A654BBJ5
• Organism: Staphylococcus pasteuri strain JS7
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 925677..936720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BJG87_RS04480 (BJG87_04400)	-	926409..927134 (+)	726	WP_046467432.1	type 1 glutamine amidotransferase	-
BJG87_RS04485 (BJG87_04405)	-	927520..928506 (-)	987	WP_029056008.1	FUSC family protein	-
BJG87_RS04490 (BJG87_04410)	map	928672..929427 (+)	756	WP_017637857.1	type I methionyl aminopeptidase	-
BJG87_RS04495 (BJG87_04415)	-	929578..929964 (+)	387	WP_017637856.1	DUF2543 family protein	-
BJG87_RS04500 (BJG87_04420)	liaF	929979..930680 (+)	702	WP_017637855.1	cell wall-active antibiotics response protein LiaF	-
BJG87_RS04505 (BJG87_04425)	vraS	930677..931720 (+)	1044	WP_017637854.1	sensor histidine kinase	Regulator
BJG87_RS04510 (BJG87_04430)	vraR	931710..932339 (+)	630	WP_017637853.1	two-component system response regulator VraR	Regulator
BJG87_RS04515 (BJG87_04435)	-	932428..933666 (-)	1239	WP_017637852.1	YihY/virulence factor BrkB family protein	-
BJG87_RS04520 (BJG87_04440)	-	933949..934233 (-)	285	WP_046467433.1	hypothetical protein	-
BJG87_RS04525 (BJG87_04445)	-	934238..934702 (-)	465	WP_017637850.1	low molecular weight protein-tyrosine-phosphatase	-
BJG87_RS04530 (BJG87_04450)	-	934864..935046 (+)	183	WP_037555624.1	DUF1128 domain-containing protein	-
BJG87_RS04535 (BJG87_04455)	-	935060..936301 (+)	1242	WP_046467434.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40047.46 Da
• Isoelectric Point: 6.2449

>NTDB_id=198514 BJG87_RS04505 WP_017637854.1 930677..931720(+) (vraS) [Staphylococcus pasteuri strain JS7]
MNHYIRAIGSMLILTYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWINS
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=198514 BJG87_RS04505 WP_017637854.1 930677..931720(+) (vraS) [Staphylococcus pasteuri strain JS7]
ATGAATCACTATATAAGAGCAATAGGCTCTATGCTCATTTTAACGTATAGTATGTTAACCGCATTTTTATTTATTGATAA
AGTATTTGTTAACATCATCTATTTTCAAGGTATGTTCTATACACAGATTTTTGGCATACCTGTATTCTTATTTTTAAACA
TCATCGTGATATTATTATGTATCATTGTAGGTTCCGTTTTAGCTTATAAAATTAATCAACAGAATGACTGGATTAATTCT
CAAATAGAACGATCTATTGAAGGTGAAACAGTTGGTATCAATGACCAAAATATTGAATTATATAGTGAAACGCTGGAAAT
ATATCATACACTTGTACCATTAAATCAGGAATTACATCGATTAAGAATGAAAACACAAAACTTAACTAATGAAAACTACA
ACATGAACGATGTAAAAGTTAAAAAGATTATTGAAGACGAAAGACAACGTCTAGCTAGAGAATTACATGACTCAGTAAGT
CAACAATTATTCGCTGCGAGTATGATGTTATCAGCGATTAAAGAAACTAAATTAGAACCCCCATTAGACCAACAAATTCC
AGTTTTAGAGAAAATGGTACAAGATTCACAACTTGAAATGAGAGCTTTATTATTACATTTACGACCTCTAGGGTTGAAAG
ATAAGTCCTTAGGTGAAGGAATTAAAGATTTAGTTATAGATCTTCAAAAGAAAGTTCCGATGAAAGTTGTACATGAAATA
CAAGAATTTAAAGTTCCTAAAGGTATCGAAGATCATTTATTTAGAATTACTCAAGAAGCTATTTCAAATACATTAAGACA
TTCTAATGGCACTAGAGTGACGGTTGAACTATTTAATAAGCAAGATTATTTATTATTACGTATACAAGATAATGGTAAAG
GGTTTAATGTTGATGAAAAATTGGAACAAAGCTATGGTTTAAAAAATATGAGAGAACGTGCATTAGAAATTGGTGCTACA
TTCCATATCGTTTCGTTACCTGATTCCGGAACACGTATAGAAGTTAAAGCCCCATTGAACAAGGAGGATTCTTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A654BBJ5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.524	100	0.945