Detailed information NTG0198479

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BJD96_RS05010
• Genome accession: NZ_CP017460
• Coordinates: 1085243..1086286 (+)
• Length: 347 a.a.
• NCBI ID: WP_096808929.1
• Uniprot ID: A0A291JJJ1
• Organism: Staphylococcus nepalensis strain JS1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1080243..1091286

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BJD96_RS04985 (BJD96_04920)	-	1081295..1082020 (+)	726	WP_096808920.1	type 1 glutamine amidotransferase	-
BJD96_RS04990 (BJD96_04925)	-	1082121..1083107 (-)	987	WP_096808922.1	FUSC family protein	-
BJD96_RS04995 (BJD96_04930)	map	1083285..1084037 (+)	753	WP_096808923.1	type I methionyl aminopeptidase	-
BJD96_RS05000 (BJD96_04935)	-	1084142..1084528 (+)	387	WP_096808925.1	hypothetical protein	-
BJD96_RS05005 (BJD96_04940)	liaF	1084545..1085246 (+)	702	WP_096808927.1	cell wall-active antibiotics response protein LiaF	-
BJD96_RS05010 (BJD96_04945)	vraS	1085243..1086286 (+)	1044	WP_096808929.1	sensor histidine kinase	Regulator
BJD96_RS05015 (BJD96_04950)	vraR	1086276..1086905 (+)	630	WP_096808931.1	response regulator transcription factor	Regulator
BJD96_RS05020 (BJD96_04955)	-	1086978..1088069 (-)	1092	WP_096808934.1	YihY/virulence factor BrkB family protein	-
BJD96_RS05025 (BJD96_04960)	-	1088358..1088642 (-)	285	WP_096808936.1	YtxH domain-containing protein	-
BJD96_RS05030 (BJD96_04965)	-	1088649..1089113 (-)	465	WP_096808938.1	low molecular weight protein-tyrosine-phosphatase	-
BJD96_RS05035 (BJD96_04970)	-	1089246..1089449 (+)	204	WP_096808941.1	DUF1128 family protein	-
BJD96_RS05040 (BJD96_04975)	-	1089464..1090705 (+)	1242	WP_096823777.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39940.35 Da
• Isoelectric Point: 6.0563

>NTDB_id=198479 BJD96_RS05010 WP_096808929.1 1085243..1086286(+) (vraS) [Staphylococcus nepalensis strain JS1]
MNHYIRAIGSMLILVYSTFFAMFFIDKVFVNIIYFQGMIYTQIFGIPVLLFINLLVILLCIIVGSVLAYKINQQNHWLQD
QIERSIEGQTVGINDQNIELYNETIELYQALVPLNQEVHKLRMKTQNLTNESYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELQAPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGQGIKDLVVDLQKKVPMKVVHDI
EDFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDDGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSNAD

Nucleotide

• Length: 1044 bp

>NTDB_id=198479 BJD96_RS05010 WP_096808929.1 1085243..1086286(+) (vraS) [Staphylococcus nepalensis strain JS1]
ATGAATCACTACATAAGAGCAATAGGGTCAATGTTGATATTAGTATATAGTACTTTTTTCGCCATGTTTTTTATAGACAA
AGTATTTGTTAATATCATATATTTCCAAGGCATGATTTACACACAAATATTTGGCATACCAGTTTTATTATTTATAAACT
TGTTAGTTATATTACTTTGTATCATCGTTGGATCTGTATTAGCATATAAAATTAATCAACAGAATCATTGGTTACAAGAT
CAAATTGAGCGCTCCATAGAAGGCCAAACAGTAGGTATCAATGACCAAAATATAGAGTTGTACAATGAAACCATTGAATT
ATATCAAGCACTGGTACCACTTAATCAAGAAGTTCACAAGTTGCGTATGAAAACGCAAAATTTAACAAACGAATCATATA
ATATGAATGACGTGAAAGTTAAAAAAATAATAGAAGACGAACGACAAAGGTTGGCTCGTGAACTACATGATTCTGTAAGC
CAACAATTATTTGCAGCAAGCATGATGCTTTCAGCAATTAAAGAAACTGAATTACAAGCGCCTTTAGATCAACAAATTCC
AGTACTCGAAAAAATGGTTCAAGATTCACAATTAGAAATGCGCGCATTACTATTACATTTAAGACCAATTGGTTTGAAGG
ATAAATCACTAGGCCAAGGTATCAAAGATTTAGTTGTTGACTTGCAGAAAAAAGTACCCATGAAAGTCGTACACGATATT
GAAGACTTCAAAGTACCCAAAGGTATTGAAGATCACTTATTTCGGATTACCCAAGAGGCAATTTCAAATACATTAAGACA
TTCGAAAGGTACTAAAGTTACAATTGAATTATTTAATAGAGAAGAATATTTATTATTACGTATACAAGATGACGGTAAAG
GCTTTAACGTAGATGATAAGGTAGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGCGCCCTTGAAATTGGTGCAACT
TTCCATATCGTATCTCTGCCAGATTCAGGCACGCGAATTGAAGTCAAGGCCCCATTAAATAAGGAGGATTCAAATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A291JJJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.744	100	0.867