Detailed information NTG0198444

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BJG88_RS05150
• Genome accession: NZ_CP017459
• Coordinates: 1107862..1108905 (+)
• Length: 347 a.a.
• NCBI ID: WP_096808929.1
• Uniprot ID: A0A291JJJ1
• Organism: Staphylococcus nepalensis strain JS9
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1102862..1113905

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BJG88_RS05125 (BJG88_05040)	-	1103914..1104639 (+)	726	WP_096808920.1	type 1 glutamine amidotransferase	-
BJG88_RS05130 (BJG88_05045)	-	1104740..1105726 (-)	987	WP_096808922.1	FUSC family protein	-
BJG88_RS05135 (BJG88_05050)	map	1105904..1106656 (+)	753	WP_096808923.1	type I methionyl aminopeptidase	-
BJG88_RS05140 (BJG88_05055)	-	1106761..1107147 (+)	387	WP_096808925.1	hypothetical protein	-
BJG88_RS05145 (BJG88_05060)	liaF	1107164..1107865 (+)	702	WP_096808927.1	cell wall-active antibiotics response protein LiaF	-
BJG88_RS05150 (BJG88_05065)	vraS	1107862..1108905 (+)	1044	WP_096808929.1	sensor histidine kinase	Regulator
BJG88_RS05155 (BJG88_05070)	vraR	1108895..1109524 (+)	630	WP_096808931.1	response regulator transcription factor	Regulator
BJG88_RS05160 (BJG88_05075)	-	1109597..1110688 (-)	1092	WP_108909265.1	YihY/virulence factor BrkB family protein	-
BJG88_RS05165 (BJG88_05080)	-	1110977..1111261 (-)	285	WP_096808936.1	YtxH domain-containing protein	-
BJG88_RS05170 (BJG88_05085)	-	1111268..1111732 (-)	465	WP_096808938.1	low molecular weight protein-tyrosine-phosphatase	-
BJG88_RS05175 (BJG88_05090)	-	1111865..1112068 (+)	204	WP_096808941.1	DUF1128 family protein	-
BJG88_RS05180 (BJG88_05095)	-	1112083..1113324 (+)	1242	WP_096808943.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39940.35 Da
• Isoelectric Point: 6.0563

>NTDB_id=198444 BJG88_RS05150 WP_096808929.1 1107862..1108905(+) (vraS) [Staphylococcus nepalensis strain JS9]
MNHYIRAIGSMLILVYSTFFAMFFIDKVFVNIIYFQGMIYTQIFGIPVLLFINLLVILLCIIVGSVLAYKINQQNHWLQD
QIERSIEGQTVGINDQNIELYNETIELYQALVPLNQEVHKLRMKTQNLTNESYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELQAPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGQGIKDLVVDLQKKVPMKVVHDI
EDFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDDGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSNAD

Nucleotide

• Length: 1044 bp

>NTDB_id=198444 BJG88_RS05150 WP_096808929.1 1107862..1108905(+) (vraS) [Staphylococcus nepalensis strain JS9]
ATGAATCACTACATAAGAGCAATAGGGTCAATGTTGATATTAGTATATAGTACTTTTTTCGCCATGTTTTTTATAGACAA
AGTATTTGTTAATATCATATATTTCCAAGGCATGATTTACACACAAATATTTGGCATACCAGTTTTATTATTTATAAACT
TGTTAGTTATATTACTTTGTATCATCGTTGGATCTGTATTAGCATATAAAATTAATCAACAGAATCATTGGTTACAAGAT
CAAATTGAGCGCTCCATAGAAGGCCAAACAGTAGGTATCAATGACCAAAATATAGAGTTGTACAATGAAACCATTGAATT
ATATCAAGCACTGGTACCACTTAATCAAGAAGTTCACAAGTTGCGTATGAAAACGCAAAATTTAACAAACGAATCATATA
ATATGAATGACGTGAAAGTTAAAAAAATAATAGAAGACGAACGACAAAGGTTGGCTCGTGAACTACATGATTCTGTAAGC
CAACAATTATTTGCAGCAAGCATGATGCTTTCAGCAATTAAAGAAACTGAATTACAAGCGCCTTTAGATCAACAAATTCC
AGTACTCGAAAAAATGGTTCAAGATTCACAATTAGAAATGCGCGCATTACTATTACATTTAAGACCAATTGGTTTGAAGG
ATAAATCACTAGGCCAAGGTATCAAAGATTTAGTTGTTGACTTGCAGAAAAAAGTACCCATGAAAGTCGTACACGATATT
GAAGACTTCAAAGTACCCAAAGGTATTGAAGATCACTTATTTCGGATTACCCAAGAGGCAATTTCAAATACATTAAGACA
TTCGAAAGGTACTAAAGTTACAATTGAATTATTTAATAGAGAAGAATATTTATTATTACGTATACAAGATGACGGTAAAG
GCTTTAACGTAGATGATAAGGTAGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGCGCCCTTGAAATTGGTGCAACT
TTCCATATCGTATCTCTGCCAGATTCAGGCACGCGAATTGAAGTCAAGGCCCCATTAAATAAGGAGGATTCAAATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A291JJJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.744	100	0.867