Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   BJG88_RS04750 Genome accession   NZ_CP017459
Coordinates   1031459..1032175 (-) Length   238 a.a.
NCBI ID   WP_096808852.1    Uniprot ID   A0A291JJD1
Organism   Staphylococcus nepalensis strain JS9     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1026459..1037175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BJG88_RS04730 (BJG88_04650) - 1027184..1027408 (+) 225 WP_096808848.1 sulfurtransferase TusA family protein -
  BJG88_RS04735 (BJG88_04655) - 1027780..1028742 (+) 963 WP_096808849.1 LacI family DNA-binding transcriptional regulator -
  BJG88_RS04740 (BJG88_04660) - 1028821..1030302 (+) 1482 WP_096808850.1 sucrose-6-phosphate hydrolase -
  BJG88_RS04745 (BJG88_04665) - 1030303..1031268 (+) 966 WP_096823774.1 carbohydrate kinase family protein -
  BJG88_RS04750 (BJG88_04670) agrA 1031459..1032175 (-) 717 WP_096808852.1 quorum-sensing response regulator AgrA Regulator
  BJG88_RS04755 (BJG88_04675) agrC 1032188..1033483 (-) 1296 WP_096808853.1 quorum-sensing sensor histidine kinase AgrC -
  BJG88_RS04760 (BJG88_04680) agrD 1033514..1033651 (-) 138 WP_096808854.1 cyclic lactone autoinducer peptide AgrD -
  BJG88_RS04765 (BJG88_04685) - 1033654..1034223 (-) 570 WP_096808855.1 accessory gene regulator AgrB -
  BJG88_RS04770 (BJG88_04690) - 1034970..1035755 (-) 786 WP_103373159.1 carbon-nitrogen family hydrolase -
  BJG88_RS04775 (BJG88_04695) - 1035906..1036535 (-) 630 WP_096808857.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27921.68 Da        Isoelectric Point: 4.8804

>NTDB_id=198443 BJG88_RS04750 WP_096808852.1 1031459..1032175(-) (agrA) [Staphylococcus nepalensis strain JS9]
MKIFICEDDERQRENLVSIINNYIMIEEKPMEIEVATSDPYEVLEHAKELKDIGCYFLDIQLEADINGIKLASEIRKYDP
VSNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPDELKSRVIDCLETSETRLKLLSKESTVETIELKRGSNSVYVQYDDVM
FFESSSNSHRLIAHLDNRQIEFYGNLKAIDNLDERFFRCHNSFVINRHNIESIDSKSRIVYFKNNEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=198443 BJG88_RS04750 WP_096808852.1 1031459..1032175(-) (agrA) [Staphylococcus nepalensis strain JS9]
ATGAAAATATTCATTTGTGAAGATGATGAGAGACAACGTGAAAATTTGGTTTCTATTATCAATAATTACATCATGATAGA
AGAAAAACCGATGGAAATTGAAGTAGCAACCTCTGATCCTTATGAGGTATTGGAACATGCAAAGGAACTTAAAGATATCG
GTTGTTACTTTCTAGACATACAATTAGAAGCTGATATTAATGGTATTAAATTAGCGAGCGAAATCCGAAAATATGATCCA
GTCAGTAATATCATTTTCGTCACTAGTCATAGTGAACTGACCTATCTGACATTTGTTTATAAAGTTGCGGCTATGGATTT
TATTTTCAAGGATGATCCTGATGAATTGAAATCAAGAGTTATTGATTGTCTTGAAACTTCTGAAACACGATTGAAATTAC
TTTCTAAAGAAAGTACTGTAGAAACAATTGAATTAAAACGTGGAAGCAATTCTGTTTATGTACAATACGATGATGTAATG
TTCTTTGAGTCTTCCTCTAATTCTCATCGTTTAATTGCCCATTTAGATAATAGACAAATTGAATTCTATGGTAACTTGAA
AGCAATCGACAATTTAGATGAACGCTTTTTCAGATGCCATAATAGTTTCGTTATTAACAGGCACAATATTGAATCTATTG
ATTCTAAATCACGTATTGTTTACTTTAAAAATAACGAACACTGTTACGCTTCCGTACGTAATGTAAAAAAAATTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A291JJD1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

83.613

100

0.836

Multiple sequence alignment