Detailed information    

insolico Bioinformatically predicted

Overview

Name   sxy/tfoX   Type   Regulator
Locus tag   A4C50_RS18580 Genome accession   NZ_CP017434
Coordinates   3517963..3518592 (-) Length   209 a.a.
NCBI ID   WP_000839159.1    Uniprot ID   A0AAV3HCB2
Organism   Escherichia coli O157:H7 strain 1130     
Function   positive regulator of competence gene (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3506885..3529766 3517963..3518592 within 0


Gene organization within MGE regions


Location: 3506885..3529766
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4C50_RS18515 (A4C50_18515) - 3506885..3507904 (+) 1020 WP_001299351.1 tyrosine-type recombinase/integrase -
  A4C50_RS18520 (A4C50_18520) yccA 3508312..3508971 (+) 660 WP_000375128.1 FtsH protease modulator YccA -
  A4C50_RS18525 (A4C50_18525) tusE 3509062..3509391 (+) 330 WP_000904442.1 sulfurtransferase TusE -
  A4C50_RS18530 (A4C50_18530) yccX 3509388..3509666 (-) 279 WP_000048252.1 acylphosphatase -
  A4C50_RS18535 (A4C50_18535) rlmI 3509761..3510951 (+) 1191 WP_000116288.1 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI -
  A4C50_RS18540 (A4C50_18540) hspQ 3511009..3511326 (+) 318 WP_001295356.1 heat shock protein HspQ -
  A4C50_RS18545 (A4C50_18545) yccU 3511371..3511784 (-) 414 WP_000665217.1 CoA-binding protein -
  A4C50_RS18555 (A4C50_18555) csgI 3511957..3512619 (+) 663 WP_000847791.1 DUF2057 family protein -
  A4C50_RS18560 (A4C50_18560) mgsA 3512715..3513173 (+) 459 WP_000424181.1 methylglyoxal synthase -
  A4C50_RS18565 (A4C50_18565) helD 3513205..3515259 (-) 2055 WP_001301436.1 DNA helicase IV -
  A4C50_RS18570 (A4C50_18570) yccF 3515382..3515828 (+) 447 WP_001261230.1 YccF domain-containing protein -
  A4C50_RS18575 (A4C50_18575) yccS 3515838..3518000 (+) 2163 WP_000875023.1 YccS family putative transporter -
  A4C50_RS18580 (A4C50_18580) sxy/tfoX 3517963..3518592 (-) 630 WP_000839159.1 CRP-S regulon transcriptional coactivator Sxy Regulator
  A4C50_RS18585 (A4C50_18585) sulA 3518811..3519320 (+) 510 WP_000288710.1 SOS-induced cell division inhibitor SulA -
  A4C50_RS18595 (A4C50_18595) ompA 3519677..3520717 (+) 1041 WP_000750416.1 porin OmpA -
  A4C50_RS18600 (A4C50_18600) matP 3520793..3521245 (-) 453 WP_000877161.1 macrodomain Ter protein MatP -
  A4C50_RS18605 (A4C50_18605) ycbZ 3521431..3523191 (+) 1761 WP_000156526.1 AAA family ATPase -
  A4C50_RS18610 (A4C50_18610) fabA 3523260..3523778 (+) 519 WP_000227927.1 bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase -
  A4C50_RS18615 (A4C50_18615) rmf 3523848..3524015 (-) 168 WP_000828650.1 ribosome modulation factor -
  A4C50_RS18620 (A4C50_18620) pqiC 3524271..3524834 (-) 564 WP_000759107.1 membrane integrity-associated transporter subunit PqiC -
  A4C50_RS18625 (A4C50_18625) pqiB 3524831..3526471 (-) 1641 WP_000445550.1 intermembrane transport protein PqiB -
  A4C50_RS18630 (A4C50_18630) pqiA 3526476..3527729 (-) 1254 WP_000333170.1 membrane integrity-associated transporter subunit PqiA -
  A4C50_RS18635 (A4C50_18635) uup 3527859..3529766 (-) 1908 WP_000053083.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 24173.05 Da        Isoelectric Point: 9.1942

>NTDB_id=198118 A4C50_RS18580 WP_000839159.1 3517963..3518592(-) (sxy/tfoX) [Escherichia coli O157:H7 strain 1130]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKYPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=198118 A4C50_RS18580 WP_000839159.1 3517963..3518592(-) (sxy/tfoX) [Escherichia coli O157:H7 strain 1130]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAATATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA

Domains

Predicted by InterproScan.

TfoX N-terminal domain (TfoX_N)

(14-106)

TfoX C-terminal domain (TfoX_C)

(116-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sxy/tfoX Escherichia coli BW25113 strain K-12

99.522

100

0.995

Multiple sequence alignment