Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CD007_RS02955 Genome accession   NZ_CP021903
Coordinates   566695..567336 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain ge28     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 561695..572336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CD007_RS02925 (CD007_02925) ydfE 562894..563517 (-) 624 WP_041850747.1 flavin reductase family protein -
  CD007_RS02930 (CD007_02930) ydfF 563607..564287 (+) 681 WP_003244115.1 winged helix-turn-helix domain-containing protein -
  CD007_RS02935 (CD007_02935) ydfG 564367..564810 (-) 444 WP_014478970.1 carboxymuconolactone decarboxylase family protein -
  CD007_RS02940 (CD007_02940) - 564896..565075 (-) 180 WP_010886421.1 hypothetical protein -
  CD007_RS02945 (CD007_02945) - 565072..565215 (-) 144 WP_041850748.1 hypothetical protein -
  CD007_RS02950 (CD007_02950) ydfH 565479..566702 (+) 1224 WP_041850749.1 two-component system sensor histidine kinase YdfH -
  CD007_RS02955 (CD007_02955) vraR 566695..567336 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  CD007_RS02960 (CD007_02960) pleJ 567452..569626 (+) 2175 WP_041850750.1 MMPL family transporter -
  CD007_RS02965 (CD007_02965) cesA 570038..570940 (-) 903 WP_003234180.1 carboxylesterase -
  CD007_RS02970 (CD007_02970) ydfK 571143..571832 (-) 690 WP_015252719.1 DUF554 domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=198084 CD007_RS02955 WP_003244318.1 566695..567336(+) (vraR) [Bacillus subtilis strain ge28]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=198084 CD007_RS02955 WP_003244318.1 566695..567336(+) (vraR) [Bacillus subtilis strain ge28]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTCGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAGGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCGATCAGAGGAAATGTGCTGTTGCAGCCTGATATCCTCAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362