Detailed information NTG0198057

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BI283_RS05000
• Genome accession: NZ_CP017430
• Coordinates: 1093528..1094571 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain MR4
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1088528..1099571

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BI283_RS04975 (BI283_04945)	-	1089531..1090250 (+)	720	WP_105966989.1	glutamine amidotransferase	-
BI283_RS04980 (BI283_04950)	-	1090333..1091319 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
BI283_RS04985 (BI283_04955)	map	1091539..1092303 (+)	765	WP_060803962.1	type I methionyl aminopeptidase	-
BI283_RS04990 (BI283_04960)	-	1092419..1092814 (+)	396	WP_002481665.1	hypothetical protein	-
BI283_RS04995 (BI283_04965)	liaF	1092830..1093531 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
BI283_RS05000 (BI283_04970)	vraS	1093528..1094571 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
BI283_RS05005 (BI283_04975)	vraR	1094561..1095190 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
BI283_RS05010 (BI283_04980)	-	1095261..1095839 (-)	579	WP_002481661.1	carbonic anhydrase	-
BI283_RS05015 (BI283_04985)	-	1096047..1097123 (-)	1077	WP_002481660.1	YihY/virulence factor BrkB family protein	-
BI283_RS05020 (BI283_04990)	-	1097254..1097544 (-)	291	WP_002481659.1	hypothetical protein	-
BI283_RS05025 (BI283_04995)	-	1097552..1098016 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
BI283_RS05030 (BI283_05000)	-	1098240..1098446 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=198057 BI283_RS05000 WP_002481663.1 1093528..1094571(+) (vraS) [Staphylococcus simulans strain MR4]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=198057 BI283_RS05000 WP_002481663.1 1093528..1094571(+) (vraS) [Staphylococcus simulans strain MR4]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATATTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTATACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGGGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCGCTTGATCAGCAAATTCC
GACACTAGAAAAGATGGTACAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862