Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   BI282_RS04615 Genome accession   NZ_CP017428
Coordinates   1018701..1019417 (-) Length   238 a.a.
NCBI ID   WP_002481723.1    Uniprot ID   -
Organism   Staphylococcus simulans strain MR3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1013701..1024417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BI282_RS04595 (BI282_04575) - 1014846..1015487 (+) 642 WP_002481727.1 redox-sensing transcriptional repressor Rex -
  BI282_RS04600 (BI282_04580) - 1015538..1015762 (-) 225 WP_002481726.1 sulfurtransferase TusA family protein -
  BI282_RS04605 (BI282_04585) - 1015818..1016906 (-) 1089 WP_070463416.1 YeeE/YedE family protein -
  BI282_RS04610 (BI282_04590) - 1017142..1018626 (+) 1485 WP_105967007.1 GH32 C-terminal domain-containing protein -
  BI282_RS04615 (BI282_04595) agrA 1018701..1019417 (-) 717 WP_002481723.1 LytTR family DNA-binding domain-containing protein Regulator
  BI282_RS14265 - 1019420..1020226 (-) 807 WP_315941006.1 GHKL domain-containing protein -
  BI282_RS04625 (BI282_04605) - 1020761..1020898 (-) 138 WP_023015908.1 cyclic lactone autoinducer peptide -
  BI282_RS04630 (BI282_04610) - 1020898..1021476 (-) 579 WP_002481720.1 accessory gene regulator AgrB -
  BI282_RS04640 (BI282_04615) - 1022257..1023057 (-) 801 WP_105967004.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27762.55 Da        Isoelectric Point: 4.6392

>NTDB_id=198027 BI282_RS04615 WP_002481723.1 1018701..1019417(-) (agrA) [Staphylococcus simulans strain MR3]
MKIIICEDDVQQREHIESIIENYIMIEEKPLEVALSTGDPYEVLEFAKATNEICCYFLDIQLDSDINGIKLGSELRNYDS
VGSIIFITSHSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESSLETIELKRGSNSVYVNYDDVM
FFESSAKSHRLIAHLDNRQIEFYGNLKDLSQLDDRFFRCHNSYVINRNNIEEVISKEREVYFKNGEHCYISVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=198027 BI282_RS04615 WP_002481723.1 1018701..1019417(-) (agrA) [Staphylococcus simulans strain MR3]
GTGAAGATTATTATATGCGAAGATGATGTACAACAGCGTGAACACATTGAATCCATCATTGAAAATTATATTATGATTGA
AGAAAAACCTTTAGAAGTGGCGCTCTCAACGGGTGATCCTTATGAGGTATTAGAATTCGCTAAAGCTACAAATGAGATTT
GTTGTTACTTCTTAGATATTCAGTTAGATTCTGATATTAACGGTATTAAGCTTGGCAGCGAACTTAGAAACTATGATTCT
GTCGGCAGTATTATCTTTATTACTAGCCACAGTGAACTCACTTATCTTACTTTCGTTTATAAAGTAGCAGCCATGGACTT
TATTTTTAAAGATGACCCTTCAGAAATGAAATCTCGAATTATTGATTGTATCGAAACTGCATTGACGAGACTACAGTTGC
TTTCAAAAGAATCTAGTCTCGAAACAATTGAGTTAAAACGTGGCAGTAACTCAGTCTATGTTAATTACGATGATGTTATG
TTCTTTGAATCCTCGGCAAAATCACATCGTTTAATTGCGCATTTAGACAATCGTCAAATCGAATTTTATGGCAACTTAAA
AGATTTAAGCCAATTAGATGACCGCTTCTTCCGTTGTCACAATAGTTACGTCATTAATCGCAATAACATCGAAGAAGTAA
TATCTAAAGAACGTGAGGTCTACTTTAAAAATGGTGAACACTGTTATATCTCAGTAAGAAATTTAAAGAAAATCTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

79.412

100

0.794

Multiple sequence alignment