Detailed information NTG0196568

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: BHS01_RS03345
• Genome accession: NZ_CP017195
• Coordinates: 659055..661331 (+)
• Length: 758 a.a.
• NCBI ID: WP_109834906.1
• Uniprot ID: A0A7L4WCJ6
• Organism: Lactococcus paracarnosus strain TMW 2.1615
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 654055..666331

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BHS01_RS03335 (BHS01_03330)	dnaG	655847..657694 (+)	1848	WP_109834907.1	DNA primase	-
BHS01_RS03340 (BHS01_03335)	rpoD	657706..658827 (+)	1122	WP_109835564.1	RNA polymerase sigma factor RpoD	-
BHS01_RS03345 (BHS01_03340)	clpC	659055..661331 (+)	2277	WP_109834906.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
BHS01_RS03350 (BHS01_03345)	def	661372..661992 (-)	621	WP_109834905.1	peptide deformylase	-
BHS01_RS03355 (BHS01_03350)	uvrB	662164..664152 (+)	1989	WP_109834904.1	excinuclease ABC subunit UvrB	-
BHS01_RS03360 (BHS01_03355)	-	664358..665164 (+)	807	WP_109834903.1	transporter substrate-binding domain-containing protein	-
BHS01_RS03365 (BHS01_03360)	-	665393..666217 (+)	825	WP_109834902.1	transporter substrate-binding domain-containing protein	-

Sequence

Protein

• Length: 758 a.a.
• Molecular weight: 84106.00 Da
• Isoelectric Point: 4.7810

>NTDB_id=196568 BHS01_RS03345 WP_109834906.1 659055..661331(+) (clpC) [Lactococcus paracarnosus strain TMW 2.1615]
MLCQNCELNEATIHLYTNMNGTKKQNDLCQNCYQIMKAGGRENLLGGSAVNPTKNQSDNNFNPFDDLFGTLGNNANRANN
RSDQSTPPTQSGRGGNGNGGRGSSKAKGMLEDFGFNVTESARKGEIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMKEISSRKDVILFIDEIHEIVGAGAAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILRGIQSRYEDYHHVSYTDEAIEQ
AAILSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFIDPEEIAKRIQSSEDAKNDALRSEDFEKAAHFRDQIAKLRELSKQ
KLADEDTPIITEKDIESIIEEKTHIPVGDLKEKEQTQLINLSDDLKGHVIGQDEAIDKIAKAVRRNRVGLGKANRPIGSF
MFVGPTGVGKTELAKQLALELFGSQNSMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEIEK
AHPDVMHMFLQILDDGRLTDAQGRTISFKDTIIIMTSNAGTGKVEANVGFGAAREGLTNSVLGQLGDFFSPEFMNRFDAI
IEFKTLSKENLLKIVDLMLADVNAQIKRNEIHLEVTQEVKEKLVELGYDPKMGARPLRRTIQDHIEDKIADFYIEHPDYK
NLLADLIDDEIVISAVAVADQDDTTAITSTVSDDNETE

Nucleotide

• Length: 2277 bp

>NTDB_id=196568 BHS01_RS03345 WP_109834906.1 659055..661331(+) (clpC) [Lactococcus paracarnosus strain TMW 2.1615]
ATGCTCTGTCAAAACTGTGAACTTAATGAAGCAACCATTCACCTTTATACAAATATGAATGGCACTAAAAAGCAAAATGA
TCTTTGCCAAAACTGTTATCAAATTATGAAAGCTGGAGGTCGCGAAAATCTGCTAGGTGGTTCAGCTGTTAACCCAACAA
AAAATCAATCAGATAATAACTTTAATCCCTTTGACGACTTATTTGGTACGCTAGGCAATAATGCAAATCGTGCCAATAAT
CGCTCTGATCAATCAACACCGCCGACCCAATCTGGCAGAGGCGGAAATGGTAATGGTGGTAGAGGAAGTAGTAAGGCCAA
AGGGATGTTAGAAGACTTTGGCTTTAATGTGACCGAAAGTGCCCGTAAAGGGGAGATCGATCCTGTAATCGGCCGAGATC
AAGAGATCACGCGTGTTATAGAAATTTTGAATCGTCGAACTAAAAATAACCCTGTCTTAATTGGGGAACCAGGTGTTGGT
AAAACGGCAGTTGTAGAAGGTCTAGCACAAAAAATAGTTGACGGCGATGTGCCGCAAAAACTACAAAATAAAGAAGTGAT
CCGACTTGACGTGGTCAGTCTGGTTCAAGGAACTGGTATCCGTGGTCAATTTGAAGAACGGATGCAAAAATTAATGAAAG
AAATTTCTAGTCGTAAAGACGTGATTCTGTTCATTGATGAAATCCATGAAATTGTTGGTGCCGGTGCAGCCGGTGATGGC
AATATGGATGCTGGTAATATCTTAAAACCAGCGCTTGCCCGTGGTGAGTTACAACTTGTCGGGGCGACGACACTTAATGA
GTACCGGATCATTGAAAAAGATGCGGCCTTAGAACGTCGGATGCAGCCAGTTAAAGTAGATGAGCCATCTGTTGAAGAAA
CGATTACGATTTTACGTGGGATTCAAAGTCGCTATGAAGACTACCATCATGTGAGCTACACAGATGAGGCAATCGAACAG
GCAGCAATTTTATCTAATCGCTATATTCAAGATAGGTTCTTACCAGATAAGGCAATTGATTTATTAGATGAGTCTGGTTC
TAAGAAAAATCTGACGCTAAAATTTATCGATCCTGAAGAAATTGCCAAACGCATTCAGTCGTCTGAGGATGCTAAAAATG
ATGCCCTTCGGTCTGAGGATTTTGAAAAGGCAGCCCATTTTCGTGACCAGATTGCTAAATTACGTGAATTATCGAAGCAG
AAGCTGGCAGATGAAGATACACCGATCATCACAGAAAAAGATATCGAATCTATTATCGAAGAAAAAACGCATATTCCTGT
TGGTGATTTAAAAGAAAAAGAACAAACACAGTTAATCAATTTGTCAGATGACTTAAAGGGACACGTGATTGGACAAGATG
AAGCAATCGATAAGATTGCTAAAGCGGTGCGTCGTAATCGTGTTGGCTTAGGTAAGGCAAATCGACCAATTGGTAGCTTT
ATGTTTGTTGGCCCAACTGGTGTTGGTAAGACAGAATTAGCTAAGCAATTAGCTTTGGAACTCTTTGGTAGTCAGAACAG
CATGATTCGCTTTGACATGAGTGAATATATGGAAAAACATAGTGTGGCTAAATTAATTGGTGCACCTCCAGGGTATGTTG
GCTATGAAGAAGCGGGCCAGTTAACTGAAAAAGTCCGCCGCAATCCCTACTCACTGATTTTACTTGATGAGATTGAAAAA
GCACATCCAGATGTCATGCATATGTTCTTGCAAATTCTAGATGATGGTCGCTTGACAGATGCACAGGGTAGAACGATTAG
CTTTAAGGATACGATTATCATCATGACATCAAATGCTGGTACCGGTAAGGTAGAAGCGAATGTTGGCTTTGGTGCGGCTC
GTGAAGGCCTGACCAATTCTGTTTTGGGTCAACTAGGTGATTTCTTTAGTCCTGAATTTATGAATCGATTTGATGCCATC
ATAGAGTTTAAGACACTTAGCAAGGAAAATCTGCTTAAAATAGTTGATTTGATGTTAGCAGATGTGAATGCGCAAATCAA
ACGCAATGAGATTCATTTGGAAGTGACACAAGAGGTCAAAGAAAAATTAGTTGAACTGGGTTATGATCCTAAAATGGGTG
CTAGACCTTTACGTCGAACAATTCAGGATCATATCGAAGATAAGATTGCTGATTTCTACATCGAACATCCAGACTACAAG
AACCTGTTAGCAGATCTGATTGATGATGAAATTGTCATATCGGCAGTAGCAGTTGCTGATCAGGATGACACGACAGCTAT
TACATCAACTGTCTCTGACGATAATGAAACTGAGTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (646-716)

• AAA lid domain (AAA_lid_9) (290-388)

• AAA domain (Cdc48 subfamily) (AAA_2) (475-640)

• ATPase family associated with various cellular activities (AAA) (AAA) (152-270)

3D structure

• AlphaFold DB: A0A7L4WCJ6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	82.337	97.098	0.799
clpE	Streptococcus mutans UA159	76.408	98.417	0.752
clpE	Streptococcus pneumoniae Rx1	75.782	96.966	0.735
clpE	Streptococcus pneumoniae D39	75.782	96.966	0.735
clpE	Streptococcus pneumoniae R6	75.782	96.966	0.735
clpE	Streptococcus pneumoniae TIGR4	75.646	96.966	0.734
clpC	Bacillus subtilis subsp. subtilis str. 168	49.783	91.161	0.454
clpC	Streptococcus thermophilus LMD-9	46.395	84.169	0.391
clpC	Streptococcus thermophilus LMG 18311	46.395	84.169	0.391
clpC	Streptococcus pneumoniae Rx1	47.727	81.266	0.388
clpC	Streptococcus pneumoniae D39	47.727	81.266	0.388
clpC	Streptococcus pneumoniae TIGR4	47.727	81.266	0.388
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.403	81.266	0.385
clpC	Streptococcus mutans UA159	46.341	81.135	0.376