Detailed information NTG0196537

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: BHS00_RS03180
• Genome accession: NZ_CP017194
• Coordinates: 643895..646171 (+)
• Length: 758 a.a.
• NCBI ID: WP_097025123.1
• Uniprot ID: -
• Organism: Lactococcus carnosus strain TMW 2.1612
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 638895..651171

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BHS00_RS03170 (BHS00_03150)	dnaG	640686..642533 (+)	1848	WP_097025125.1	DNA primase	-
BHS00_RS03175 (BHS00_03155)	rpoD	642545..643666 (+)	1122	WP_047916626.1	RNA polymerase sigma factor RpoD	-
BHS00_RS03180 (BHS00_03160)	clpC	643895..646171 (+)	2277	WP_097025123.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
BHS00_RS03185 (BHS00_03165)	def	646211..646831 (-)	621	WP_097025122.1	peptide deformylase	-
BHS00_RS03190 (BHS00_03170)	uvrB	647003..648991 (+)	1989	WP_097025121.1	excinuclease ABC subunit UvrB	-
BHS00_RS03195 (BHS00_03175)	-	649196..650002 (+)	807	WP_097025120.1	transporter substrate-binding domain-containing protein	-
BHS00_RS03200 (BHS00_03180)	-	650230..651054 (+)	825	WP_097025119.1	transporter substrate-binding domain-containing protein	-

Sequence

Protein

• Length: 758 a.a.
• Molecular weight: 84072.03 Da
• Isoelectric Point: 4.8651

>NTDB_id=196537 BHS00_RS03180 WP_097025123.1 643895..646171(+) (clpC) [Lactococcus carnosus strain TMW 2.1612]
MLCQNCQLNEATIHLYTNMNGTKKQNDLCQNCYQIMKAGGRENLLGGSAANPAKNQSDNNFNPFDDLFGTLGNNASRANN
RSDQATPPTQSGRGGNGNGGRGNSKAKGMLEDFGFNVTESARKGEIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMKEISSRKDVILFIDEIHEIVGAGAAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILRGIQSRYEDYHHVSYTDEAIEQ
AAILSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFIDPEEIAKRIQSSEDAKNDALRSEDFEKAAHFRDQIAKLRELSKQ
KLADEDTPIITEKDIESIIEEKTHIPVGDLKEKEQTQLINLSDDLKGHVIGQDEAIDKIAKAVRRNRVGLGKANRPIGSF
MFVGPTGVGKTELAKQLALELFGSQNSMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEIEK
AHPDVMHMFLQILDDGRLTDAQGRTISFKDTIIIMTSNAGTGKVEANVGFGAAREGLTNSVLGQLGDFFSPEFMNRFDAI
IEFKTLSKENLLKIVDLMLADVNGQIKRNEIHLEVTKEVKEKLVELGYDPKMGARPLRRTIQDHIEDKIADFYIEHPDYK
NLLADLIDDEIVISAVAVADQDDTTAIRSTVSDDNETE

Nucleotide

• Length: 2277 bp

>NTDB_id=196537 BHS00_RS03180 WP_097025123.1 643895..646171(+) (clpC) [Lactococcus carnosus strain TMW 2.1612]
ATGCTCTGTCAAAACTGTCAACTTAATGAAGCAACCATTCACCTTTATACAAATATGAATGGCACTAAAAAGCAAAATGA
TCTTTGCCAAAACTGTTATCAAATTATGAAAGCTGGAGGTCGCGAAAATCTGCTAGGTGGTTCAGCTGCTAACCCAGCAA
AAAATCAATCAGATAATAACTTTAATCCATTTGACGACCTATTTGGTACGCTAGGCAATAATGCAAGTCGTGCCAATAAT
CGTTCTGACCAAGCAACACCGCCGACCCAATCTGGCAGAGGTGGAAATGGTAATGGCGGTAGAGGTAATAGCAAGGCCAA
AGGTATGTTAGAAGATTTTGGCTTTAATGTGACGGAAAGCGCCCGTAAAGGGGAGATCGATCCTGTTATCGGCCGAGATC
AAGAGATCACGCGTGTCATAGAAATTTTGAATCGTCGGACTAAAAATAACCCTGTCTTAATCGGGGAACCAGGTGTCGGG
AAAACGGCAGTTGTAGAAGGACTAGCACAAAAAATAGTCGACGGTGATGTACCGCAAAAACTGCAAAATAAAGAAGTGAT
TCGACTTGACGTGGTCAGTCTGGTACAAGGAACAGGTATCCGTGGTCAATTTGAAGAACGGATGCAAAAATTAATGAAAG
AAATTTCTAGTCGTAAAGACGTGATTCTGTTCATTGATGAAATCCATGAGATTGTTGGTGCCGGTGCAGCCGGTGATGGC
AATATGGATGCTGGTAATATCTTGAAACCAGCGCTTGCCCGTGGCGAGTTACAACTTGTCGGGGCGACGACACTTAATGA
GTACCGGATCATTGAAAAAGATGCGGCCTTAGAACGTCGGATGCAGCCAGTTAAAGTAGATGAGCCATCTGTTGAAGAAA
CGATTACGATTTTACGTGGGATTCAAAGTCGCTATGAAGACTACCATCATGTGAGCTACACAGATGAGGCAATCGAACAG
GCAGCGATTTTATCTAATCGCTATATTCAAGATCGATTCTTACCAGATAAGGCAATTGATTTATTAGATGAGTCTGGTTC
CAAAAAAAATCTGACATTAAAATTTATCGATCCTGAAGAAATTGCCAAGCGCATTCAGTCATCTGAGGATGCTAAAAATG
ATGCCCTTCGGTCTGAGGATTTTGAAAAGGCAGCACATTTTCGTGACCAGATTGCTAAATTACGTGAATTATCGAAGCAG
AAGCTTGCGGATGAAGATACACCGATCATTACAGAAAAAGATATCGAATCTATTATCGAAGAAAAAACGCATATTCCTGT
TGGTGATTTAAAAGAAAAAGAACAAACACAGTTAATCAATTTGTCGGATGACTTAAAGGGACACGTGATTGGACAAGATG
AAGCAATCGATAAGATTGCTAAGGCAGTACGTCGTAATCGTGTTGGCTTAGGTAAGGCAAATCGACCAATTGGTAGCTTT
ATGTTTGTTGGCCCAACTGGTGTTGGTAAAACAGAATTGGCTAAGCAATTAGCTTTGGAACTCTTTGGTAGTCAGAACAG
CATGATTCGCTTTGATATGAGTGAATACATGGAAAAACATAGTGTGGCTAAATTGATTGGGGCACCTCCAGGGTATGTTG
GCTATGAAGAAGCTGGTCAATTAACTGAGAAAGTCCGCCGCAATCCCTACTCACTGATTTTACTTGATGAGATTGAAAAA
GCACATCCAGATGTCATGCATATGTTCTTACAAATTCTAGATGATGGTCGCTTGACAGATGCACAAGGTAGAACGATTAG
CTTTAAGGATACGATTATCATCATGACGTCAAATGCTGGTACCGGTAAGGTAGAGGCTAATGTCGGCTTTGGTGCGGCTC
GTGAAGGCTTGACCAATTCTGTCTTGGGTCAACTAGGTGATTTCTTTAGTCCTGAATTTATGAATCGCTTCGATGCTATC
ATTGAATTTAAGACACTTAGCAAGGAAAATCTACTTAAAATAGTTGATTTGATGTTAGCAGATGTCAATGGGCAAATCAA
ACGCAATGAGATTCATTTGGAAGTGACAAAAGAAGTCAAAGAAAAATTAGTTGAACTAGGTTATGATCCTAAAATGGGTG
CTAGACCTTTACGTCGAACAATTCAGGATCATATCGAAGATAAGATTGCTGATTTCTACATCGAACATCCAGACTACAAG
AACCTGTTAGCAGATCTGATTGATGATGAGATTGTCATATCGGCAGTAGCAGTTGCTGATCAGGATGACACGACAGCTAT
TAGATCAACTGTCTCTGACGACAATGAAACTGAGTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (646-716)

• AAA lid domain (AAA_lid_9) (290-388)

• AAA domain (Cdc48 subfamily) (AAA_2) (475-640)

• ATPase family associated with various cellular activities (AAA) (AAA) (152-270)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	82.09	97.23	0.798
clpE	Streptococcus mutans UA159	76.139	98.417	0.749
clpE	Streptococcus pneumoniae Rx1	75.646	96.966	0.734
clpE	Streptococcus pneumoniae D39	75.646	96.966	0.734
clpE	Streptococcus pneumoniae R6	75.646	96.966	0.734
clpE	Streptococcus pneumoniae TIGR4	75.51	96.966	0.732
clpC	Bacillus subtilis subsp. subtilis str. 168	49.783	91.161	0.454
clpC	Streptococcus thermophilus LMD-9	46.395	84.169	0.391
clpC	Streptococcus thermophilus LMG 18311	46.395	84.169	0.391
clpC	Streptococcus pneumoniae Rx1	47.565	81.266	0.387
clpC	Streptococcus pneumoniae D39	47.565	81.266	0.387
clpC	Streptococcus pneumoniae TIGR4	47.565	81.266	0.387
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.403	81.266	0.385
clpC	Streptococcus mutans UA159	46.179	81.135	0.375