Detailed information
Bioinformatically predicted
Overview
| Name | comGB | Type | Machinery gene |
| Locus tag | LCW_RS03350 | Genome accession | NZ_CP017124 |
| Coordinates | 657425..658426 (+) | Length | 333 a.a. |
| NCBI ID | WP_069468028.1 | Uniprot ID | - |
| Organism | Latilactobacillus curvatus strain WiKim38 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 658479..705440 | 657425..658426 | flank | 53 |
Gene organization within MGE regions
Location: 657425..705440
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LCW_RS03350 (LCW_03350) | comGB | 657425..658426 (+) | 1002 | WP_069468028.1 | type II secretion system F family protein | Machinery gene |
| LCW_RS03355 (LCW_03355) | - | 658479..659903 (-) | 1425 | WP_069468029.1 | recombinase family protein | - |
| LCW_RS03360 (LCW_03360) | - | 660012..660713 (-) | 702 | WP_069468030.1 | hypothetical protein | - |
| LCW_RS03365 (LCW_03365) | - | 660706..661128 (-) | 423 | WP_069468031.1 | hypothetical protein | - |
| LCW_RS03370 (LCW_03370) | - | 661121..662029 (-) | 909 | WP_069468032.1 | ParA family protein | - |
| LCW_RS03375 (LCW_03375) | - | 662129..663115 (-) | 987 | WP_069468033.1 | DUF4236 domain-containing protein | - |
| LCW_RS03380 (LCW_03380) | - | 663252..663881 (-) | 630 | WP_143435696.1 | hypothetical protein | - |
| LCW_RS03385 (LCW_03385) | - | 663989..664834 (-) | 846 | WP_069468034.1 | hypothetical protein | - |
| LCW_RS03390 (LCW_03390) | - | 664894..665295 (-) | 402 | WP_069468035.1 | ImmA/IrrE family metallo-endopeptidase | - |
| LCW_RS03395 (LCW_03395) | - | 665295..665630 (-) | 336 | WP_069468036.1 | helix-turn-helix domain-containing protein | - |
| LCW_RS03400 (LCW_03400) | - | 665779..666006 (+) | 228 | WP_069468037.1 | helix-turn-helix domain-containing protein | - |
| LCW_RS10080 | - | 666025..666189 (+) | 165 | WP_155760082.1 | hypothetical protein | - |
| LCW_RS03405 (LCW_03405) | - | 666249..666800 (+) | 552 | WP_237023253.1 | helix-turn-helix domain-containing protein | - |
| LCW_RS10505 | - | 666797..666949 (+) | 153 | WP_186738769.1 | BOW99_gp33 family protein | - |
| LCW_RS03415 (LCW_03415) | - | 667241..667438 (+) | 198 | WP_069468039.1 | hypothetical protein | - |
| LCW_RS03420 (LCW_03420) | bet | 667438..668205 (+) | 768 | WP_069468040.1 | phage recombination protein Bet | - |
| LCW_RS03425 (LCW_03425) | - | 668087..668956 (+) | 870 | WP_237023254.1 | PD-(D/E)XK nuclease-like domain-containing protein | - |
| LCW_RS03430 (LCW_03430) | ssb | 668968..669384 (+) | 417 | WP_069468042.1 | single-stranded DNA-binding protein | Machinery gene |
| LCW_RS03435 (LCW_03435) | - | 669395..670360 (+) | 966 | WP_069468043.1 | DnaD domain-containing protein | - |
| LCW_RS03445 (LCW_03445) | - | 670560..671090 (+) | 531 | WP_069468045.1 | helix-turn-helix domain-containing protein | - |
| LCW_RS03450 (LCW_03450) | - | 671062..671268 (+) | 207 | WP_081303843.1 | DUF6877 family protein | - |
| LCW_RS10085 | - | 671268..671429 (+) | 162 | WP_155760086.1 | hypothetical protein | - |
| LCW_RS03455 (LCW_03455) | - | 671429..671884 (+) | 456 | WP_081326636.1 | class I SAM-dependent methyltransferase | - |
| LCW_RS03460 (LCW_03460) | - | 671955..672242 (+) | 288 | WP_069468047.1 | hypothetical protein | - |
| LCW_RS10090 | - | 672256..672426 (+) | 171 | WP_155760088.1 | hypothetical protein | - |
| LCW_RS03465 (LCW_03465) | - | 672460..672798 (+) | 339 | WP_065825501.1 | hypothetical protein | - |
| LCW_RS03470 (LCW_03470) | - | 672809..673156 (+) | 348 | WP_069468048.1 | YopX family protein | - |
| LCW_RS10455 | - | 673156..673284 (+) | 129 | WP_257784602.1 | hypothetical protein | - |
| LCW_RS03475 (LCW_03475) | - | 673284..673748 (+) | 465 | WP_039098605.1 | DUF1064 domain-containing protein | - |
| LCW_RS03480 (LCW_03480) | - | 673760..673963 (+) | 204 | WP_065825503.1 | hypothetical protein | - |
| LCW_RS03485 (LCW_03485) | - | 673983..674165 (+) | 183 | WP_065825504.1 | hypothetical protein | - |
| LCW_RS03490 (LCW_03490) | - | 674165..674401 (+) | 237 | WP_039098607.1 | helix-turn-helix domain-containing protein | - |
| LCW_RS03495 (LCW_03495) | - | 674515..674940 (+) | 426 | WP_065825505.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| LCW_RS03500 (LCW_03500) | - | 675434..676339 (+) | 906 | WP_069468049.1 | hypothetical protein | - |
| LCW_RS10095 | - | 676583..676753 (+) | 171 | WP_155760091.1 | hypothetical protein | - |
| LCW_RS03505 (LCW_03505) | - | 676753..677577 (+) | 825 | WP_069468050.1 | terminase small subunit | - |
| LCW_RS03510 (LCW_03510) | - | 677570..678844 (+) | 1275 | WP_069468051.1 | PBSX family phage terminase large subunit | - |
| LCW_RS03515 (LCW_03515) | - | 678855..680303 (+) | 1449 | WP_069468052.1 | phage portal protein | - |
| LCW_RS03520 (LCW_03520) | - | 680245..680559 (+) | 315 | WP_069468053.1 | ribosomal-processing cysteine protease Prp | - |
| LCW_RS03525 (LCW_03525) | - | 680562..681755 (+) | 1194 | WP_069468054.1 | minor capsid protein | - |
| LCW_RS03530 (LCW_03530) | - | 681924..682568 (+) | 645 | WP_069468055.1 | capsid assembly scaffolding protein Gp46 family protein | - |
| LCW_RS03535 (LCW_03535) | - | 682581..682937 (+) | 357 | WP_069468056.1 | hypothetical protein | - |
| LCW_RS03540 (LCW_03540) | - | 682960..684021 (+) | 1062 | WP_039098617.1 | major capsid protein | - |
| LCW_RS03545 (LCW_03545) | - | 684036..684356 (+) | 321 | WP_155760093.1 | phage head-tail connector protein | - |
| LCW_RS03550 (LCW_03550) | - | 684422..684742 (+) | 321 | WP_237023255.1 | hypothetical protein | - |
| LCW_RS03555 (LCW_03555) | - | 684690..685235 (+) | 546 | WP_069468058.1 | hypothetical protein | - |
| LCW_RS03560 (LCW_03560) | - | 685237..685602 (+) | 366 | WP_069468539.1 | hypothetical protein | - |
| LCW_RS03565 (LCW_03565) | - | 685615..686079 (+) | 465 | WP_069468059.1 | phage tail tube protein | - |
| LCW_RS09935 | - | 686136..686327 (+) | 192 | Protein_693 | Ig-like domain-containing protein | - |
| LCW_RS03570 (LCW_03570) | - | 686351..686755 (+) | 405 | WP_069468060.1 | DUF6096 family protein | - |
| LCW_RS03575 (LCW_03575) | - | 686776..687156 (+) | 381 | WP_081326601.1 | hypothetical protein | - |
| LCW_RS03580 (LCW_03580) | - | 687168..691985 (+) | 4818 | WP_069468061.1 | hypothetical protein | - |
| LCW_RS03585 (LCW_03585) | - | 692001..692360 (+) | 360 | WP_069468062.1 | DUF6711 family protein | - |
| LCW_RS03590 (LCW_03590) | - | 692372..696373 (+) | 4002 | WP_069468063.1 | gp58-like family protein | - |
| LCW_RS03595 (LCW_03595) | - | 696370..696816 (+) | 447 | WP_069468064.1 | DUF1617 family protein | - |
| LCW_RS03600 (LCW_03600) | - | 696816..697043 (+) | 228 | WP_069468065.1 | hypothetical protein | - |
| LCW_RS03605 (LCW_03605) | - | 697062..697535 (+) | 474 | WP_081326602.1 | phage holin family protein | - |
| LCW_RS03610 (LCW_03610) | - | 697532..697810 (+) | 279 | WP_069468066.1 | phage holin family protein | - |
| LCW_RS03615 (LCW_03615) | - | 697810..698616 (+) | 807 | WP_069468067.1 | N-acetylmuramoyl-L-alanine amidase | - |
| LCW_RS03620 (LCW_03620) | - | 698658..699734 (-) | 1077 | WP_069468068.1 | AbiH family protein | - |
| LCW_RS03625 (LCW_03625) | - | 699849..700109 (+) | 261 | WP_069468069.1 | hypothetical protein | - |
| LCW_RS03630 (LCW_03630) | - | 700139..700420 (+) | 282 | WP_069468070.1 | hypothetical protein | - |
| LCW_RS03635 (LCW_03635) | - | 700471..700662 (-) | 192 | WP_069468071.1 | helix-turn-helix domain-containing protein | - |
| LCW_RS03640 (LCW_03640) | - | 700676..701068 (-) | 393 | WP_069468072.1 | hypothetical protein | - |
| LCW_RS03645 (LCW_03645) | - | 701174..701629 (-) | 456 | WP_069468073.1 | hypothetical protein | - |
| LCW_RS03650 (LCW_03650) | - | 701632..701892 (-) | 261 | WP_069468074.1 | hypothetical protein | - |
| LCW_RS10100 | - | 701911..702084 (-) | 174 | WP_155760095.1 | hypothetical protein | - |
| LCW_RS03655 (LCW_03655) | - | 702110..702511 (-) | 402 | WP_069468075.1 | homing endonuclease associated repeat-containing protein | - |
| LCW_RS03660 (LCW_03660) | - | 702592..702837 (+) | 246 | WP_237023256.1 | competence protein ComGC | - |
| LCW_RS03665 (LCW_03665) | - | 702869..703261 (+) | 393 | WP_069468076.1 | hypothetical protein | - |
| LCW_RS10225 (LCW_03670) | - | 703326..703553 (+) | 228 | WP_158070299.1 | hypothetical protein | - |
| LCW_RS10510 | - | 703519..703602 (+) | 84 | Protein_716 | type II secretion system protein | - |
| LCW_RS03675 (LCW_03675) | - | 703624..704004 (+) | 381 | WP_004270914.1 | ComGF family competence protein | - |
| LCW_RS03680 (LCW_03680) | - | 703982..704305 (+) | 324 | WP_039099486.1 | hypothetical protein | - |
| LCW_RS03685 (LCW_03685) | - | 704421..705440 (+) | 1020 | WP_335617917.1 | class I SAM-dependent methyltransferase | - |
Sequence
Protein
Download Length: 333 a.a. Molecular weight: 37831.02 Da Isoelectric Point: 9.6278
>NTDB_id=195893 LCW_RS03350 WP_069468028.1 657425..658426(+) (comGB) [Latilactobacillus curvatus strain WiKim38]
MKTKTTVQFNTEFMLLLGRLLQNGFSLQQALEFMPIVFPTQKQWLHQVQTGLEAGKRLGPSLAAVSFPTHLVAQIELTEL
QGNLGECLLHLGQLQRIQQKRRRELVGVIAYPCFLLLFLGALIGMMQIYLFPEIAQFNPTTSATSPLQLFFRVMGTFVIM
AGGLISVYLFRWHRRPLLQRLAAAFRWPFIGKTLQAYYQYCLLFDLATCLNNGLNLAEMHQLTHRLAKTSWLVQLMQQLE
TAVQKGGTLLANLADGVFYPPELQLVLAKGGPLQQMAKEVDLLAVIKYDELQRQLKQKVNWLQPLLFILIGIIIICTYLS
ILLPLYHTMEGIS
MKTKTTVQFNTEFMLLLGRLLQNGFSLQQALEFMPIVFPTQKQWLHQVQTGLEAGKRLGPSLAAVSFPTHLVAQIELTEL
QGNLGECLLHLGQLQRIQQKRRRELVGVIAYPCFLLLFLGALIGMMQIYLFPEIAQFNPTTSATSPLQLFFRVMGTFVIM
AGGLISVYLFRWHRRPLLQRLAAAFRWPFIGKTLQAYYQYCLLFDLATCLNNGLNLAEMHQLTHRLAKTSWLVQLMQQLE
TAVQKGGTLLANLADGVFYPPELQLVLAKGGPLQQMAKEVDLLAVIKYDELQRQLKQKVNWLQPLLFILIGIIIICTYLS
ILLPLYHTMEGIS
Nucleotide
Download Length: 1002 bp
>NTDB_id=195893 LCW_RS03350 WP_069468028.1 657425..658426(+) (comGB) [Latilactobacillus curvatus strain WiKim38]
ATGAAGACTAAAACCACTGTTCAATTCAATACTGAATTTATGTTGCTGTTAGGGCGCTTACTGCAAAATGGTTTTTCTTT
ACAACAAGCACTTGAGTTCATGCCGATTGTTTTTCCGACACAAAAGCAGTGGCTGCATCAGGTGCAAACTGGGTTAGAAG
CAGGAAAACGACTAGGACCAAGCTTAGCGGCGGTTTCGTTTCCAACACACCTTGTTGCACAGATTGAATTGACTGAGTTG
CAGGGAAACTTAGGCGAGTGTTTGTTACATCTTGGCCAATTACAGCGAATTCAACAGAAACGGCGTAGAGAGTTAGTTGG
CGTAATTGCCTATCCCTGTTTTCTACTCCTTTTTCTCGGGGCGTTGATTGGGATGATGCAGATTTATCTTTTTCCGGAAA
TCGCGCAGTTTAACCCAACAACTTCGGCGACATCACCATTACAACTATTTTTTAGAGTGATGGGGACATTCGTTATTATG
GCTGGTGGTCTGATTAGTGTGTATTTATTCCGTTGGCATCGGCGACCGCTATTACAACGATTGGCGGCGGCATTTAGATG
GCCGTTCATCGGTAAAACGTTGCAGGCTTACTATCAGTATTGCTTATTATTTGATTTAGCGACTTGCCTGAATAACGGCT
TAAACTTGGCCGAAATGCATCAGCTTACACATCGTTTGGCGAAAACATCGTGGCTTGTACAATTAATGCAACAACTTGAA
ACGGCTGTCCAAAAGGGGGGCACGCTATTAGCGAACTTAGCGGATGGCGTTTTTTATCCACCTGAGCTGCAATTAGTGCT
CGCTAAGGGAGGTCCATTACAACAGATGGCCAAGGAGGTTGATCTGCTTGCAGTCATTAAATACGATGAACTGCAACGGC
AATTGAAACAGAAGGTGAATTGGCTACAACCGCTCTTGTTTATCCTAATTGGGATCATCATTATTTGTACCTATCTCAGT
ATTTTATTACCGCTATATCATACAATGGAGGGAATTTCATGA
ATGAAGACTAAAACCACTGTTCAATTCAATACTGAATTTATGTTGCTGTTAGGGCGCTTACTGCAAAATGGTTTTTCTTT
ACAACAAGCACTTGAGTTCATGCCGATTGTTTTTCCGACACAAAAGCAGTGGCTGCATCAGGTGCAAACTGGGTTAGAAG
CAGGAAAACGACTAGGACCAAGCTTAGCGGCGGTTTCGTTTCCAACACACCTTGTTGCACAGATTGAATTGACTGAGTTG
CAGGGAAACTTAGGCGAGTGTTTGTTACATCTTGGCCAATTACAGCGAATTCAACAGAAACGGCGTAGAGAGTTAGTTGG
CGTAATTGCCTATCCCTGTTTTCTACTCCTTTTTCTCGGGGCGTTGATTGGGATGATGCAGATTTATCTTTTTCCGGAAA
TCGCGCAGTTTAACCCAACAACTTCGGCGACATCACCATTACAACTATTTTTTAGAGTGATGGGGACATTCGTTATTATG
GCTGGTGGTCTGATTAGTGTGTATTTATTCCGTTGGCATCGGCGACCGCTATTACAACGATTGGCGGCGGCATTTAGATG
GCCGTTCATCGGTAAAACGTTGCAGGCTTACTATCAGTATTGCTTATTATTTGATTTAGCGACTTGCCTGAATAACGGCT
TAAACTTGGCCGAAATGCATCAGCTTACACATCGTTTGGCGAAAACATCGTGGCTTGTACAATTAATGCAACAACTTGAA
ACGGCTGTCCAAAAGGGGGGCACGCTATTAGCGAACTTAGCGGATGGCGTTTTTTATCCACCTGAGCTGCAATTAGTGCT
CGCTAAGGGAGGTCCATTACAACAGATGGCCAAGGAGGTTGATCTGCTTGCAGTCATTAAATACGATGAACTGCAACGGC
AATTGAAACAGAAGGTGAATTGGCTACAACCGCTCTTGTTTATCCTAATTGGGATCATCATTATTTGTACCTATCTCAGT
ATTTTATTACCGCTATATCATACAATGGAGGGAATTTCATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGB | Latilactobacillus sakei subsp. sakei 23K |
56.973 |
100 |
0.577 |