Detailed information NTG0195811

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FORC45_RS14135
• Genome accession: NZ_CP017115
• Coordinates: 2701332..2702219 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain FORC_045
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2696332..2707219

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FORC45_RS14100	-	2696351..2696443 (+)	93	WP_010956583.1	hypothetical protein	-
FORC45_RS14105 (FORC45_2550)	-	2696551..2697048 (-)	498	WP_001065268.1	glutathione peroxidase	-
FORC45_RS14110	-	2697058..2697318 (-)	261	WP_001791974.1	hypothetical protein	-
FORC45_RS14120	-	2697700..2697813 (-)	114	Protein_2613	hypothetical protein	-
FORC45_RS14125 (FORC45_2551)	-	2698472..2700472 (-)	2001	WP_000776740.1	ABC transporter permease	-
FORC45_RS14130 (FORC45_2552)	-	2700469..2701224 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
FORC45_RS14135 (FORC45_2553)	braS	2701332..2702219 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FORC45_RS14140 (FORC45_2554)	braR	2702230..2702895 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FORC45_RS14145 (FORC45_2555)	-	2702921..2703121 (-)	201	WP_000604727.1	hypothetical protein	-
FORC45_RS14150 (FORC45_2556)	-	2703319..2704743 (+)	1425	WP_000953748.1	alkaline phosphatase	-
FORC45_RS14950 (FORC45_2557)	-	2704803..2704904 (-)	102	WP_000731972.1	SE2200 family small protein	-
FORC45_RS14160 (FORC45_2558)	-	2705026..2705481 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FORC45_RS14165 (FORC45_2559)	-	2705726..2706487 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=195811 FORC45_RS14135 WP_000143417.1 2701332..2702219(-) (braS) [Staphylococcus aureus strain FORC_045]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=195811 FORC45_RS14135 WP_000143417.1 2701332..2702219(-) (braS) [Staphylococcus aureus strain FORC_045]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99