Detailed information NTG0195466

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: A2V17_RS14260
• Genome accession: NZ_CP017090
• Coordinates: 2759468..2760355 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain ISU935 isolate ST5
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2754468..2765355

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2V17_RS14225 (A2V17_13955)	-	2754487..2754579 (+)	93	WP_010956583.1	hypothetical protein	-
A2V17_RS14230 (A2V17_13960)	-	2754687..2755184 (-)	498	WP_001065268.1	glutathione peroxidase	-
A2V17_RS14235 (A2V17_13965)	-	2755194..2755454 (-)	261	WP_001791974.1	hypothetical protein	-
A2V17_RS14245 (A2V17_13970)	-	2755836..2755949 (-)	114	Protein_2672	hypothetical protein	-
A2V17_RS14250 (A2V17_13980)	-	2756608..2758608 (-)	2001	WP_000776751.1	ABC transporter permease	-
A2V17_RS14255 (A2V17_13985)	-	2758605..2759360 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
A2V17_RS14260 (A2V17_13990)	braS	2759468..2760355 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
A2V17_RS14265 (A2V17_13995)	braR	2760366..2761031 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
A2V17_RS14270 (A2V17_14000)	-	2761057..2761257 (-)	201	WP_000604730.1	hypothetical protein	-
A2V17_RS14275 (A2V17_14010)	-	2761455..2762879 (+)	1425	WP_000953755.1	alkaline phosphatase	-
A2V17_RS15090 (A2V17_14015)	-	2762939..2763040 (-)	102	WP_000731976.1	SE2200 family small protein	-
A2V17_RS14285 (A2V17_14020)	-	2763162..2763617 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
A2V17_RS14290 (A2V17_14025)	-	2763862..2764623 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=195466 A2V17_RS14260 WP_000143425.1 2759468..2760355(-) (braS) [Staphylococcus aureus strain ISU935 isolate ST5]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=195466 A2V17_RS14260 WP_000143425.1 2759468..2760355(-) (braS) [Staphylococcus aureus strain ISU935 isolate ST5]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1