Detailed information NTG0195412

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: A7J08_RS07805
• Genome accession: NZ_CP017088
• Coordinates: 1567588..1568637 (-)
• Length: 349 a.a.
• NCBI ID: WP_004194592.1
• Uniprot ID: A0A0N0DPM5
• Organism: Streptococcus suis strain SRD478
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1562588..1573637

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7J08_RS07780 (A7J08_07565)	nadE	1563051..1563875 (+)	825	WP_024382384.1	ammonia-dependent NAD(+) synthetase	-
A7J08_RS07790 (A7J08_07570)	-	1565114..1565641 (-)	528	WP_053867189.1	VanZ family protein	-
A7J08_RS07795 (A7J08_07575)	rlmN	1565638..1566750 (-)	1113	WP_053867188.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
A7J08_RS07800 (A7J08_07580)	-	1566759..1567400 (-)	642	WP_053867187.1	YutD-like domain-containing protein	-
A7J08_RS07805 (A7J08_07585)	sepM	1567588..1568637 (-)	1050	WP_004194592.1	SepM family pheromone-processing serine protease	Regulator
A7J08_RS07810 (A7J08_07590)	coaD	1568624..1569112 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
A7J08_RS07815 (A7J08_07595)	rsmD	1569102..1569641 (-)	540	WP_053867186.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
A7J08_RS07820 (A7J08_07600)	-	1569950..1570672 (-)	723	WP_053867185.1	serine protease	-
A7J08_RS07825 (A7J08_07605)	-	1570729..1571115 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
A7J08_RS07830 (A7J08_07610)	-	1571115..1571333 (-)	219	WP_053867190.1	YqgQ family protein	-
A7J08_RS07835 (A7J08_07615)	-	1571641..1572243 (-)	603	WP_141605036.1	response regulator transcription factor	-
A7J08_RS07840 (A7J08_07620)	-	1572240..1573334 (-)	1095	WP_172001050.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37747.80 Da
• Isoelectric Point: 4.6112

>NTDB_id=195412 A7J08_RS07805 WP_004194592.1 1567588..1568637(-) (sepM) [Streptococcus suis strain SRD478]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=195412 A7J08_RS07805 WP_004194592.1 1567588..1568637(-) (sepM) [Streptococcus suis strain SRD478]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A0N0DPM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605