Detailed information NTG0195077

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BFP67_RS05160
• Genome accession: NZ_CP017069
• Coordinates: 1088275..1089318 (+)
• Length: 347 a.a.
• NCBI ID: WP_002461334.1
• Uniprot ID: A0A853V5Y6
• Organism: Staphylococcus lugdunensis strain K93G
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1083275..1094318

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BFP67_RS05135 (BFP67_06345)	-	1083565..1084926 (-)	1362	WP_037540479.1	FAD-dependent oxidoreductase	-
BFP67_RS05140 (BFP67_06340)	-	1085060..1086040 (-)	981	WP_002492696.1	FUSC family protein	-
BFP67_RS05145 (BFP67_06335)	map	1086285..1087040 (+)	756	WP_002461338.1	type I methionyl aminopeptidase	-
BFP67_RS05150 (BFP67_06330)	-	1087166..1087552 (+)	387	WP_002477960.1	hypothetical protein	-
BFP67_RS05155 (BFP67_06325)	liaF	1087577..1088278 (+)	702	WP_002461335.1	cell wall-active antibiotics response protein LiaF	-
BFP67_RS05160 (BFP67_06320)	vraS	1088275..1089318 (+)	1044	WP_002461334.1	sensor histidine kinase	Regulator
BFP67_RS05165 (BFP67_06315)	vraR	1089308..1089937 (+)	630	WP_002461333.1	two-component system response regulator VraR	Regulator
BFP67_RS05170 (BFP67_06310)	-	1090110..1091339 (-)	1230	WP_002492699.1	YihY/virulence factor BrkB family protein	-
BFP67_RS05175 (BFP67_06305)	-	1091542..1091826 (-)	285	WP_002461330.1	YtxH domain-containing protein	-
BFP67_RS05180 (BFP67_06300)	-	1091833..1092297 (-)	465	WP_002492719.1	low molecular weight protein-tyrosine-phosphatase	-
BFP67_RS05185 (BFP67_06295)	-	1092461..1092646 (+)	186	WP_002492715.1	DUF1128 domain-containing protein	-
BFP67_RS05190 (BFP67_06290)	-	1092659..1093897 (+)	1239	WP_002461326.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39934.41 Da
• Isoelectric Point: 5.9679

>NTDB_id=195077 BFP67_RS05160 WP_002461334.1 1088275..1089318(+) (vraS) [Staphylococcus lugdunensis strain K93G]
MNHYIRAIGSMLILVYSLMIAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAFKINQQNDWIKT
QVEHAIEGETVGINDQNIELYNETIDLYHTLVPLNQELHRLRMKTQNLTNENYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHDI
EEFKVPKGLEDHLFRITQEAISNTLRHSKGTKVTVELFNKADYLLLRIQDNGIGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=195077 BFP67_RS05160 WP_002461334.1 1088275..1089318(+) (vraS) [Staphylococcus lugdunensis strain K93G]
ATGAACCACTATATTCGAGCAATCGGCTCAATGTTGATACTAGTGTATAGCTTAATGATTGCTTTTCTGTTTATTGATAA
AGTATTCGTTAATATCATTTACTTTCAAGGCATGTTTTATACACAAATATTTGGAATACCAGTATTCCTTTTCTTAAATT
TGGTTATTATTTTATTATGTATTATTGTGGGCTCTATATTAGCTTTTAAAATCAATCAACAAAATGATTGGATCAAAACA
CAAGTAGAGCATGCAATAGAAGGGGAAACAGTTGGTATAAATGATCAAAATATAGAATTGTATAATGAAACAATTGATTT
ATATCATACATTAGTTCCCTTAAATCAAGAGTTACACCGATTAAGAATGAAAACACAAAACTTAACAAATGAAAATTATA
ATTTAAATGATGTAAAAGTGAAAAAAATAATTGAAGACGAACGTCAACGTCTAGCTCGAGAATTACATGATTCAGTGAGC
CAGCAATTATTTGCAGCCAGTATGATGTTATCTGCAATTAAAGAAACAGAGCTAGAACCACCTTTAGATCAACAAATTCC
AGTTTTAGAAAAAATGGTGCAAGATTCACAACTTGAAATGAGAGCACTCTTATTACATCTAAGACCAATTGGTTTAAAGG
ACAAGTCGTTGGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAGAAAAAAGTACCGATGAAAGTGGTTCACGATATT
GAAGAATTTAAAGTGCCTAAAGGTTTAGAAGATCATTTGTTTAGAATTACTCAAGAAGCCATCTCTAATACTTTAAGACA
TTCAAAAGGAACTAAAGTTACTGTAGAATTATTTAATAAAGCAGATTATTTATTATTAAGAATACAAGATAATGGCATTG
GATTTAATGTTGATGATAAAGTCGAACAAAGTTATGGCTTGAAAAATATGCGCGAACGTGCGTTAGAAATAGGTGCAACA
TTTCATATTGTATCATTGCCTGATTCTGGAACAAGAATAGAGGTTAAAGCACCGTTAAACAAGGAGGATTCACATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A853V5Y6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.066	100	0.911