Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   CCX85_RS08730 Genome accession   NZ_CP021640
Coordinates   1742049..1742645 (-) Length   198 a.a.
NCBI ID   WP_038432673.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain JS12     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1737049..1747645
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCX85_RS08695 (CCX85_08690) - 1737108..1737413 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  CCX85_RS08700 (CCX85_08695) ruvX 1737425..1737844 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  CCX85_RS08705 (CCX85_08700) - 1737841..1738110 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  CCX85_RS08710 (CCX85_08705) spx 1738225..1738623 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  CCX85_RS08715 (CCX85_08710) recA 1738914..1740050 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  CCX85_RS08720 (CCX85_08715) cinA 1740139..1741410 (-) 1272 WP_002992182.1 competence/damage-inducible protein A Machinery gene
  CCX85_RS08725 (CCX85_08720) - 1741479..1742039 (-) 561 WP_002992183.1 DNA-3-methyladenine glycosylase I -
  CCX85_RS08730 (CCX85_08725) ruvA 1742049..1742645 (-) 597 WP_038432673.1 Holliday junction branch migration protein RuvA Machinery gene
  CCX85_RS08735 (CCX85_08730) - 1742647..1743867 (-) 1221 WP_002992187.1 MDR family MFS transporter -
  CCX85_RS08740 (CCX85_08735) hexB 1743878..1745860 (-) 1983 WP_002992189.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21865.24 Da        Isoelectric Point: 6.8836

>NTDB_id=194486 CCX85_RS08730 WP_038432673.1 1742049..1742645(-) (ruvA) [Streptococcus pyogenes strain JS12]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVDAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=194486 CCX85_RS08730 WP_038432673.1 1742049..1742645(-) (ruvA) [Streptococcus pyogenes strain JS12]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGATG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424

Multiple sequence alignment