Detailed information NTG0194473

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: CCX85_RS07490
• Genome accession: NZ_CP021640
• Coordinates: 1485197..1488025 (-)
• Length: 942 a.a.
• NCBI ID: WP_002993235.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain JS12
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1480197..1493025

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CCX85_RS07460 (CCX85_07465)	-	1480873..1481838 (+)	966	WP_020837630.1	LacI family DNA-binding transcriptional regulator	-
CCX85_RS07465 (CCX85_07470)	nusB	1481979..1482431 (-)	453	WP_002988501.1	transcription antitermination factor NusB	-
CCX85_RS07470 (CCX85_07475)	-	1482424..1482813 (-)	390	WP_101248443.1	Asp23/Gls24 family envelope stress response protein	-
CCX85_RS07475 (CCX85_07480)	efp	1482859..1483416 (-)	558	WP_002988496.1	elongation factor P	-
CCX85_RS07480 (CCX85_07485)	-	1483512..1483973 (-)	462	WP_002988493.1	deoxycytidylate deaminase	-
CCX85_RS07485 (CCX85_07490)	-	1484008..1485081 (-)	1074	WP_042361523.1	M24 family metallopeptidase	-
CCX85_RS07490 (CCX85_07495)	uvrA	1485197..1488025 (-)	2829	WP_002993235.1	excinuclease ABC subunit UvrA	Machinery gene
CCX85_RS07495 (CCX85_07500)	-	1488228..1489172 (+)	945	WP_002983147.1	magnesium transporter CorA family protein	-
CCX85_RS07500 (CCX85_07505)	-	1489305..1489961 (+)	657	WP_002983144.1	DUF1129 domain-containing protein	-
CCX85_RS07505 (CCX85_07510)	rpsR	1490092..1490331 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
CCX85_RS07510 (CCX85_07515)	ssbA	1490496..1490987 (-)	492	WP_002993238.1	single-stranded DNA-binding protein	Machinery gene
CCX85_RS07515 (CCX85_07520)	rpsF	1491009..1491299 (-)	291	WP_002983117.1	30S ribosomal protein S6	-
CCX85_RS07520 (CCX85_07525)	-	1491472..1491765 (-)	294	WP_002983113.1	hypothetical protein	-

Sequence

Protein

• Length: 942 a.a.
• Molecular weight: 104112.30 Da
• Isoelectric Point: 6.1170

>NTDB_id=194473 CCX85_RS07490 WP_002993235.1 1485197..1488025(-) (uvrA) [Streptococcus pyogenes strain JS12]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQHLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide

• Length: 2829 bp

>NTDB_id=194473 CCX85_RS07490 WP_002993235.1 1485197..1488025(-) (uvrA) [Streptococcus pyogenes strain JS12]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTTGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGATCAAAAAACTACCAGTAAGAACCCCCGCTCAACGGTTGGTACGGTGACTGAAATCAATGA
TTATTTACGTTTACTATATGCGCGTGTGGGCACACCTTACTGTATTAATGGGCATGGGGCCATTACAGCATCTTCTGCAG
AACAAATTGTAGAGCAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCGCCTATTGTTCGCCGGAAAAAA
GGTCAACACAAAACCATTTTTGAGAAAATTCAAAAAGATGGCTATGTCCGTGTGCGGGTTGATGGGGATATTTTTGACGT
GACAGAAGTGCCGGAGCTGTCAAAAAGTAAGATGCACAACATCGAGGTGGTTATTGATCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGATTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAGAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGAGATTTAGTGCT
TTATGGTTCAGGTGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGACATTCCTTTTG
AAGGTGTTGTAACTAATGTTAATCGCCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGCTACATG
AATGAATTGACTTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCCTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAACTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATTCATGACCGCCTGACCTTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTATCACGGGCTGCTGGGACTTTATCAGGTGGGGAAAGTCAACGAATCAGGTTAGCAACACAAATTGGTTCTAACTT
ATCAGGGGTGCTCTATATCTTGGATGAGCCTTCTATTGGATTGCACCAAAGAGACAATGACCGTTTGATCGAAAGCCTGA
AAAAAATGCGTGATTTGGGTAATACCTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGACCGGGGGCAGGTGAGTTCGGTGGAGAAATTATTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTCTGGTAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGGCGATTCA
TTGAAATAAAAGGAGCAGCACAGAACAATCTTCAACACCTTGATGTTAGATTCCCACTGGGTAAATTTATTGCTGTTACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGTTACAAAAAAGGTCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTATAAAGAAAAAAATATTGCTGAAGTGCTTGACATGACTGTCGATGATGCCTTGGTATTTTTC
TCTGCTATCCCTAAAATTGCCCGAAAAATTCAAACCATTAAGGATGTTGGTTTGGGTTATGTGACCTTGGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTAGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGTAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCTACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (624-860)

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

• UvrA interaction domain (UvrA_inter) (132-238)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	84.926	100	0.849
uvrA	Streptococcus pneumoniae TIGR4	84.926	100	0.849
uvrA	Streptococcus pneumoniae D39	84.926	100	0.849