Detailed information NTG0194438

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: CCX85_RS03575
• Genome accession: NZ_CP021640
• Coordinates: 700881..702980 (-)
• Length: 699 a.a.
• NCBI ID: WP_101248346.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain JS12
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 695881..707980

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CCX85_RS03545 (CCX85_03550)	-	696358..697197 (+)	840	WP_011017679.1	thymidylate synthase	-
CCX85_RS03550 (CCX85_03555)	-	697277..697774 (+)	498	WP_002984955.1	dihydrofolate reductase	-
CCX85_RS09200 (CCX85_03560)	-	697794..697964 (+)	171	WP_002990165.1	hypothetical protein	-
CCX85_RS03560 (CCX85_03565)	clpX	698094..699323 (+)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
CCX85_RS03565 (CCX85_03570)	yihA	699333..699932 (+)	600	WP_038432912.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
CCX85_RS03570 (CCX85_03575)	-	700080..700823 (+)	744	WP_002984942.1	hypothetical protein	-
CCX85_RS03575 (CCX85_03580)	clpC	700881..702980 (-)	2100	WP_101248346.1	AAA family ATPase	Regulator
CCX85_RS03580 (CCX85_03585)	rpiA	703358..704041 (+)	684	WP_002994002.1	ribose-5-phosphate isomerase RpiA	-
CCX85_RS03585 (CCX85_03590)	-	704118..705329 (+)	1212	WP_020905095.1	phosphopentomutase	-
CCX85_RS03590 (CCX85_03595)	arsC	705348..705788 (+)	441	WP_038432915.1	arsenate reductase (glutaredoxin)	-
CCX85_RS03595 (CCX85_03600)	-	705772..706581 (+)	810	WP_038432917.1	purine-nucleoside phosphorylase	-
CCX85_RS03600 (CCX85_03605)	deoD	707244..707957 (+)	714	WP_002984928.1	purine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77384.49 Da
• Isoelectric Point: 5.8953

>NTDB_id=194438 CCX85_RS03575 WP_101248346.1 700881..702980(-) (clpC) [Streptococcus pyogenes strain JS12]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKERQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLKRLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPDVKKLQAILKEGQLVIRQNDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=194438 CCX85_RS03575 WP_101248346.1 700881..702980(-) (clpC) [Streptococcus pyogenes strain JS12]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCACTCGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGGCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTTACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCCGTCTCTAACATGGGGACT
AATGATTTAAAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTCGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGAGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGACGTCAAAAAACTTCAGGCAATCCTAAAAGAAGGACAACTAGTGA
TTAGGCAAAACGATCAGTAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

• AAA lid domain (AAA_lid_9) (259-353)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	46.942	100	0.472
clpE	Streptococcus mutans UA159	49.068	92.132	0.452
clpE	Streptococcus pneumoniae TIGR4	49.438	89.127	0.441
clpE	Streptococcus pneumoniae Rx1	49.438	89.127	0.441
clpE	Streptococcus pneumoniae D39	49.438	89.127	0.441
clpE	Streptococcus pneumoniae R6	49.438	89.127	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	44.662	95.136	0.425
clpC	Streptococcus thermophilus LMD-9	43.103	91.273	0.393
clpC	Streptococcus pneumoniae Rx1	42.025	93.276	0.392
clpC	Streptococcus pneumoniae D39	42.025	93.276	0.392
clpC	Streptococcus thermophilus LMG 18311	42.947	91.273	0.392
clpC	Streptococcus pneumoniae TIGR4	43.016	90.129	0.388
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.348	93.419	0.386
clpC	Streptococcus mutans UA159	41.875	91.559	0.383