Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AM366_RS04490 Genome accession   NZ_CP021535
Coordinates   894050..894682 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain AR_0119     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 889050..899682
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM366_RS04465 (AM366_04455) yhfG 889182..889349 (+) 168 WP_000736860.1 YhfG family protein -
  AM366_RS04470 (AM366_04460) fic 889339..889941 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AM366_RS04475 (AM366_04465) pabA 889973..890536 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  AM366_RS04480 (AM366_04470) argD 890622..891842 (+) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AM366_RS04485 (AM366_04475) yhfK 891909..893999 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AM366_RS04490 (AM366_04480) crp 894050..894682 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AM366_RS04500 (AM366_04490) yhfA 894984..895388 (+) 405 WP_001148908.1 OsmC family protein -
  AM366_RS04505 (AM366_04495) prkB 895443..896312 (-) 870 WP_001274680.1 phosphoribulokinase -
  AM366_RS04510 (AM366_04500) yheU 896366..896584 (-) 219 WP_000907085.1 YheU family protein -
  AM366_RS04515 (AM366_04505) yheT 896578..897600 (-) 1023 WP_000057379.1 hydrolase -
  AM366_RS04520 (AM366_04510) yheS 897600..899513 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=194341 AM366_RS04490 WP_000242755.1 894050..894682(-) (crp) [Escherichia coli strain AR_0119]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=194341 AM366_RS04490 WP_000242755.1 894050..894682(-) (crp) [Escherichia coli strain AR_0119]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment