Detailed information NTG0193988

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: BFM96_RS00135
• Genome accession: NZ_CP016953
• Coordinates: 45298..47508 (+)
• Length: 736 a.a.
• NCBI ID: WP_068988844.1
• Uniprot ID: -
• Organism: Streptococcus himalayensis strain HTS2
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 40298..52508

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BFM96_RS00110	-	41133..41996 (-)	864	WP_068988828.1	NAD(P)H-hydrate dehydratase	-
BFM96_RS00115	-	42008..42859 (-)	852	WP_068988829.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
BFM96_RS00120	-	43249..43983 (-)	735	WP_068988832.1	amino acid ABC transporter ATP-binding protein	-
BFM96_RS00125	-	43976..44665 (-)	690	WP_068988836.1	amino acid ABC transporter permease	-
BFM96_RS00130	-	44816..45046 (-)	231	WP_068988841.1	DUF1797 family protein	-
BFM96_RS00135	clpE	45298..47508 (+)	2211	WP_068988844.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
BFM96_RS00140	-	47596..48045 (+)	450	WP_068988845.1	NUDIX hydrolase	-
BFM96_RS00145	-	48106..48405 (+)	300	WP_068988848.1	DUF1827 family protein	-
BFM96_RS00150	-	48484..48978 (-)	495	WP_068988851.1	hypothetical protein	-
BFM96_RS00155	-	48975..50213 (-)	1239	WP_068988854.1	restriction endonuclease subunit S	-
BFM96_RS00160	-	50231..51847 (-)	1617	WP_068988857.1	class I SAM-dependent DNA methyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 82130.51 Da
• Isoelectric Point: 5.3450

>NTDB_id=193988 BFM96_RS00135 WP_068988844.1 45298..47508(+) (clpE) [Streptococcus himalayensis strain HTS2]
MLCQNCKINESTIHLYTNVNGKQRQVDLCQNCYQIMKTDPENAIFKGFSNMHQPLDPFNDFFGNLENFQQPQEPKTPPTQ
AGGAGGRGGQRGNQTPPQPKGILDEFGINVTEIARQGNIDPVIGRDEEIVRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
LAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRNDVILFIDEIHEIVGAGSAGDGNMDAGNI
LKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQQKYEDYHHVTYTDEAIEAAAVLSNR
YIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKTQATRDEDFEKAAYFRDQIAKYKELQKNKMLDQDT
PIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKAHVIGQDEAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTG
VGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEVEKAHPDVMH
MFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKVEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGIIEFKALS
KDNLLHIVHLMLEDVNQRLSSNGIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLEHPTEKSLKAVMG
SKGNILIKANTKEKEA

Nucleotide

• Length: 2211 bp

>NTDB_id=193988 BFM96_RS00135 WP_068988844.1 45298..47508(+) (clpE) [Streptococcus himalayensis strain HTS2]
ATGCTTTGTCAAAACTGTAAAATCAATGAATCAACTATCCATCTCTATACAAATGTCAATGGAAAACAACGTCAGGTTGA
CCTCTGCCAAAATTGCTACCAAATCATGAAAACAGATCCAGAAAATGCTATCTTCAAAGGTTTTAGCAACATGCACCAAC
CACTTGATCCGTTTAATGATTTCTTTGGCAATCTGGAAAATTTCCAACAACCACAAGAACCCAAAACACCTCCTACACAG
GCAGGTGGTGCTGGAGGTCGTGGTGGTCAACGAGGCAATCAAACACCGCCACAACCAAAAGGCATTTTGGACGAATTTGG
AATTAACGTCACAGAAATTGCCCGCCAAGGCAATATTGACCCCGTGATTGGCCGTGATGAGGAAATCGTTCGTGTCATTG
AGATTTTAAACCGCAGAACTAAGAACAATCCTGTACTCATCGGAGAGCCTGGGGTCGGTAAAACGGCTGTTGTAGAAGGA
TTGGCACAAAAAATCGTGGATGGAGATGTTCCCCACAAACTTCAAGGCAAGGAAGTCATTCGTCTGGATGTGGTCAGTCT
GGTTCAAGGAACGGGTATCCGTGGTCAATTTGAAGAACGCATGCAAAAGTTGATGGAGGAAATCCGCAAACGCAACGATG
TTATTCTCTTTATTGATGAAATTCATGAAATTGTCGGTGCTGGCTCTGCTGGTGACGGCAATATGGACGCAGGCAATATT
TTAAAACCTGCTCTTGCACGTGGAGAATTGCAACTGGTCGGTGCCACAACTCTCAACGAATACCGCATTATCGAAAAAGA
TGCAGCCTTGGAGCGTCGTATGCAGCCAGTCAAGGTTGATGAGCCAACAGTGGAAGAAACCATCACGATTTTGAAAGGCA
TTCAACAAAAATACGAAGACTACCACCACGTTACCTATACTGATGAGGCGATTGAAGCCGCTGCAGTCCTTTCCAATCGC
TATATCCAAGACCGTTTCTTGCCAGACAAGGCGATTGACCTCTTGGATGAAGCGGGTTCAAAAATGAACCTCACCCTCAA
TTTTGTCGATCCAAAGGTCATTGACCAACGCTTGATTGAGGCTGAAAATCTCAAAACCCAAGCCACACGAGATGAAGATT
TCGAAAAAGCAGCCTACTTCCGCGACCAGATTGCCAAATATAAGGAGCTGCAAAAAAATAAAATGCTGGATCAAGATACG
CCGATTATCAGCGAGAAAACAATCGAGCATATCATCGAGCAAAAGACCAATATTCCAGTTGGTGATTTGAAGGAAAAAGA
GCAATCCCAACTCATTCATCTAGCTGAAGACTTAAAAGCACATGTCATTGGGCAAGACGAGGCCGTGGACAAGATTGCCA
AGGCCATTCGCCGCAACCGTGTTGGACTCGGTACGCCGAATCGTCCGATCGGAAGTTTCCTCTTTGTCGGACCAACAGGG
GTCGGAAAAACGGAGCTATCCAAACAACTAGCCATCGAACTCTTTGGCTCAGCCGATAGCATGATTCGCTTTGATATGAG
TGAATATATGGAAAAACACAGCGTGGCAAAATTGGTCGGTGCCCCTCCGGGCTATGTCGGTTACGAGGAAGCAGGACAGC
TCACCGAGCGTGTGCGTCGCAATCCTTACTCCCTCATTTTGCTGGATGAGGTCGAAAAAGCCCACCCTGATGTCATGCAC
ATGTTCCTTCAGGTATTGGATGATGGCCGTTTGACCGATGGCCAAGGCCGCACAGTCAGCTTTAAAGACGCTATCATCAT
CATGACCTCCAATGCTGGTACAGGCAAGGTTGAGGCGAGCGTCGGCTTTGGAGCTGCACGCGAAGGTCGCACCAATTCTG
TTTTAGGAGAGTTAGGCAATTTCTTCAGCCCAGAATTCATGAACCGCTTTGATGGCATTATCGAATTTAAAGCCCTCAGC
AAGGACAATCTCCTTCATATCGTCCATCTCATGCTAGAGGATGTCAATCAGCGTCTCTCAAGCAATGGTATTCATCTGGA
TGTCACAGATAAAGTCAAGGAAAAACTGGTTGATTTAGGCTACGATCCGAAAATGGGGGCAAGGCCTCTGCGTAGAACCA
TTCAAGACCATATCGAAGATGCTATCACCGACTTCTACCTTGAACATCCGACCGAAAAATCCCTCAAAGCTGTTATGGGA
AGCAAGGGCAATATCCTCATCAAGGCAAATACAAAAGAAAAAGAAGCATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (283-380)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (639-713)

• AAA domain (Cdc48 subfamily) (AAA_2) (468-631)

• ATPase family associated with various cellular activities (AAA) (AAA) (145-264)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	87.871	100	0.886
clpE	Streptococcus pneumoniae D39	87.871	100	0.886
clpE	Streptococcus pneumoniae R6	87.871	100	0.886
clpE	Streptococcus pneumoniae TIGR4	87.736	100	0.885
clpE	Streptococcus mutans UA159	84.522	100	0.853
clpC	Lactococcus lactis subsp. cremoris KW2	79.806	98.234	0.784
clpC	Bacillus subtilis subsp. subtilis str. 168	50.972	90.897	0.463
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.253	86.549	0.409
clpC	Streptococcus pneumoniae TIGR4	47.826	84.375	0.404
clpC	Streptococcus pneumoniae Rx1	47.826	84.375	0.404
clpC	Streptococcus pneumoniae D39	47.826	84.375	0.404
clpC	Streptococcus thermophilus LMD-9	46.88	84.918	0.398
clpC	Streptococcus mutans UA159	46.795	84.783	0.397
clpC	Streptococcus thermophilus LMG 18311	46.314	84.783	0.393