Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   S100757_RS03160 Genome accession   NZ_CP021499
Coordinates   597365..598006 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis subsp. subtilis strain SRCM100757     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 592365..603006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  S100757_RS03130 (S100757_00613) ydfE 593560..594183 (-) 624 WP_014478968.1 flavin reductase family protein -
  S100757_RS03135 (S100757_00614) ydfF 594273..594953 (+) 681 WP_014478969.1 winged helix-turn-helix domain-containing protein -
  S100757_RS03140 (S100757_00615) ydfG 595033..595476 (-) 444 WP_015252723.1 carboxymuconolactone decarboxylase family protein -
  S100757_RS03145 (S100757_00616) - 595562..595741 (-) 180 WP_080019537.1 hypothetical protein -
  S100757_RS03150 - 595738..595881 (-) 144 WP_014478971.1 hypothetical protein -
  S100757_RS03155 (S100757_00617) ydfH 596149..597372 (+) 1224 WP_015252722.1 two-component system sensor histidine kinase YdfH -
  S100757_RS03160 (S100757_00618) vraR 597365..598006 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  S100757_RS03165 (S100757_00619) pleJ 598122..600296 (+) 2175 WP_046160096.1 MMPL family transporter -
  S100757_RS03170 (S100757_00620) ydfK 600354..601043 (-) 690 WP_046160097.1 DUF554 domain-containing protein -
  S100757_RS03175 (S100757_00621) ydfL 601132..601944 (-) 813 WP_087614363.1 MerR family transcriptional regulator -
  S100757_RS03180 (S100757_00622) mneP 602058..602951 (-) 894 WP_038428417.1 manganese transporter MneP -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=193314 S100757_RS03160 WP_003244318.1 597365..598006(+) (vraR) [Bacillus subtilis subsp. subtilis strain SRCM100757]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=193314 S100757_RS03160 WP_003244318.1 597365..598006(+) (vraR) [Bacillus subtilis subsp. subtilis strain SRCM100757]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTCGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAGGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCCATCAGAGGAAATGTGCTGTTGCAGCCTGATATCCTTAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362

Multiple sequence alignment