Detailed information NTG0192854

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: A7U51_RS11485
• Genome accession: NZ_CP016855
• Coordinates: 2175002..2175889 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 5118.N
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2170002..2180889

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7U51_RS11455 (A7U51_2867)	-	2170734..2171495 (+)	762	WP_000323455.1	alpha/beta hydrolase	-
A7U51_RS11460 (A7U51_2866)	-	2171740..2172195 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
A7U51_RS15665 (A7U51_04680)	-	2172317..2172418 (+)	102	WP_000731972.1	SE2200 family small protein	-
A7U51_RS11470 (A7U51_2865)	-	2172478..2173902 (-)	1425	WP_000953744.1	alkaline phosphatase	-
A7U51_RS11475 (A7U51_2864)	-	2174100..2174300 (+)	201	WP_000604728.1	hypothetical protein	-
A7U51_RS11480 (A7U51_2863)	braR	2174326..2174991 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
A7U51_RS11485 (A7U51_2862)	braS	2175002..2175889 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
A7U51_RS11490 (A7U51_2861)	-	2175997..2176752 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
A7U51_RS11495 (A7U51_04685)	-	2176749..2178749 (+)	2001	WP_000776751.1	ABC transporter permease	-
A7U51_RS11500 (A7U51_04690)	-	2179408..2179521 (+)	114	WP_001791776.1	hypothetical protein	-
A7U51_RS11510 (A7U51_04700)	-	2179903..2180163 (+)	261	WP_001789910.1	hypothetical protein	-
A7U51_RS11515 (A7U51_2857)	-	2180173..2180670 (+)	498	WP_001065268.1	glutathione peroxidase	-
A7U51_RS11520 (A7U51_04705)	-	2180778..2180870 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=192854 A7U51_RS11485 WP_000143419.1 2175002..2175889(+) (braS) [Staphylococcus aureus strain 5118.N]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=192854 A7U51_RS11485 WP_000143419.1 2175002..2175889(+) (braS) [Staphylococcus aureus strain 5118.N]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997