Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   BFC19_RS10080 Genome accession   NZ_CP016839
Coordinates   2072080..2073888 (+) Length   602 a.a.
NCBI ID   WP_119946075.1    Uniprot ID   -
Organism   Brochothrix thermosphacta strain TMW 2.1564     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2067080..2078888
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFC19_RS10055 (BFC19_09960) - 2067405..2067872 (+) 468 WP_119946072.1 glutathione peroxidase -
  BFC19_RS10060 (BFC19_09965) trpS 2067935..2068924 (-) 990 WP_232011805.1 tryptophan--tRNA ligase -
  BFC19_RS10065 (BFC19_09970) spxA 2069424..2069831 (+) 408 WP_029091611.1 transcriptional regulator SpxA -
  BFC19_RS10070 (BFC19_09975) mecA 2070090..2070770 (+) 681 WP_119946073.1 adaptor protein MecA -
  BFC19_RS10075 (BFC19_09980) - 2070891..2072003 (+) 1113 WP_119946074.1 competence protein CoiA -
  BFC19_RS10080 (BFC19_09985) pepF 2072080..2073888 (+) 1809 WP_119946075.1 oligoendopeptidase F Regulator
  BFC19_RS12980 - 2074205..2074381 (+) 177 Protein_1919 transporter substrate-binding domain-containing protein -
  BFC19_RS10085 (BFC19_09990) - 2074883..2076304 (+) 1422 WP_413486359.1 amino acid ABC transporter substrate-binding protein/permease -
  BFC19_RS10090 (BFC19_09995) - 2076285..2077013 (+) 729 WP_029091616.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 67820.89 Da        Isoelectric Point: 4.6006

>NTDB_id=192609 BFC19_RS10080 WP_119946075.1 2072080..2073888(+) (pepF) [Brochothrix thermosphacta strain TMW 2.1564]
MAGKAITRSEVPVKDTWDLTSIFETDEAWETEFKAVQVLAEEATKFQKTLGDSADQLLAALKYSDELVVRLSQVYVYASM
KHDQDTSNTEYQALNSRAESLAAKASAALSFFEPELLDIDEAVLAAFISESDELGVYAHELEQINKKRPHTLAAPEEALL
AKASEVLGSSQNTFGILNNADLRFPTIKDENGEDVEITHGLYGPLLENSDRRVRRDAFQNVYKTYKSLLNTFASTLTGQI
KQDNFNASVRKFSTARESAVFSNNIPESVHKTLLETVGNNVDLLHRYVSLRKQVLGLDELHVYDLYTPLVADVDELSFTY
EEAKQVTINALAPLGEEYVSILKEGFDKRWVDVVENKGKRSGAYSGGSYGTNPFILLNWHDTLDNLYTLVHEFGHSVHSY
LTRKNQPAVYGDYTIFLAEIASTTNENLLTDYLLKKYDDKKIQAYIINHFLDGFKGTVFRQTQFAEFEHLIHVADQEGNA
LTAEYLTDLYYGINKKYYGDALVHDEEIGNEWARIPHFYYNYYVYQYATGFSAASALAQHILDEGAPAVERYMTFLKAGN
SDYPIDVLKAAGVDMTTAKPIEDALKVFEARLAEFEAIIIEK

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=192609 BFC19_RS10080 WP_119946075.1 2072080..2073888(+) (pepF) [Brochothrix thermosphacta strain TMW 2.1564]
ATGGCTGGAAAAGCAATTACACGCTCTGAAGTGCCTGTAAAAGACACTTGGGACTTAACAAGTATTTTTGAAACAGATGA
AGCATGGGAAACAGAATTTAAAGCTGTCCAAGTATTAGCAGAAGAAGCAACTAAATTCCAAAAAACATTAGGTGATAGTG
CAGACCAGCTTCTTGCAGCTTTAAAATATAGTGATGAGCTTGTTGTTCGTTTATCACAAGTTTATGTTTATGCAAGTATG
AAACATGATCAAGATACTAGCAATACAGAGTATCAAGCGTTAAATAGTCGTGCAGAATCATTGGCTGCCAAAGCCTCAGC
TGCACTATCTTTCTTTGAACCGGAATTATTAGATATTGATGAAGCGGTACTTGCCGCCTTTATTTCTGAATCTGACGAAT
TAGGTGTATACGCGCATGAGTTAGAACAAATCAATAAGAAACGTCCTCATACATTGGCTGCTCCTGAGGAAGCGTTATTA
GCTAAAGCAAGCGAAGTATTAGGCTCATCACAAAATACTTTTGGTATTCTAAATAATGCAGATTTACGTTTTCCAACAAT
CAAAGATGAAAATGGTGAAGATGTAGAGATTACACACGGTCTATACGGTCCATTATTGGAAAATAGCGATCGTCGTGTGC
GTCGTGACGCTTTCCAAAATGTGTATAAAACGTATAAGTCATTGCTTAATACATTTGCCTCAACGTTGACTGGTCAAATT
AAGCAAGATAACTTCAATGCATCTGTTCGTAAGTTTAGTACTGCCAGAGAGTCGGCTGTTTTCAGCAATAATATTCCTGA
GTCAGTTCATAAAACATTGCTTGAAACGGTAGGGAATAATGTTGATTTATTACATCGTTATGTGAGTTTACGCAAGCAGG
TATTAGGTCTTGACGAATTGCATGTTTACGATCTTTACACACCGCTTGTAGCGGATGTAGATGAGCTTTCATTTACGTAT
GAAGAAGCTAAACAAGTAACAATTAATGCCTTAGCACCTTTGGGTGAAGAATATGTTTCTATCCTTAAAGAAGGTTTTGA
TAAGCGTTGGGTAGATGTGGTTGAAAATAAAGGGAAACGTAGTGGCGCATACTCTGGCGGTTCATACGGTACCAATCCAT
TTATTCTATTAAACTGGCATGATACATTAGATAATTTGTATACATTAGTTCATGAGTTTGGGCACAGTGTACATAGTTAT
CTCACTCGAAAAAATCAACCGGCAGTTTATGGCGATTATACAATCTTTTTAGCAGAGATTGCTTCAACTACCAATGAAAA
TTTATTGACAGATTATCTTCTGAAAAAATATGATGATAAAAAAATCCAAGCCTATATTATTAACCATTTCCTTGATGGTT
TTAAAGGTACTGTTTTCCGTCAAACACAATTTGCAGAATTTGAGCACCTTATTCATGTTGCTGATCAAGAAGGTAACGCT
TTAACAGCTGAATATCTAACTGATCTCTACTATGGTATTAATAAGAAATATTATGGTGATGCACTGGTACACGATGAAGA
AATTGGTAACGAATGGGCGCGTATTCCTCATTTCTACTACAATTATTACGTGTATCAATATGCAACTGGTTTTTCTGCAG
CTTCAGCTTTGGCACAACATATTTTGGACGAAGGAGCTCCAGCAGTAGAACGTTACATGACGTTCTTAAAAGCAGGTAAC
TCGGATTATCCAATCGATGTGTTGAAAGCTGCTGGCGTTGACATGACTACTGCAAAACCAATTGAGGATGCTTTGAAAGT
TTTCGAAGCACGTCTAGCTGAATTCGAAGCAATTATTATAGAAAAATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(205-586)

Oligopeptidase F (Peptidase_M3_N)

(115-184)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.351

98.339

0.505

Multiple sequence alignment