Detailed information    

insolico Bioinformatically predicted

Overview

Name   priA   Type   Machinery gene
Locus tag   CA922_RS14990 Genome accession   NZ_CP021268
Coordinates   3292183..3294360 (+) Length   725 a.a.
NCBI ID   WP_042754571.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila strain Birmingham     
Function   DNA puliing through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3287183..3299360
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA922_RS14970 lgt2 3287605..3289515 (-) 1911 WP_042754575.1 Dot/Icm type IV secretion system effector glucosyltransferase Lgt2/LegC8 -
  CA922_RS14975 - 3289641..3290396 (-) 756 WP_042754573.1 pteridine reductase -
  CA922_RS14980 - 3290573..3291685 (+) 1113 WP_042754572.1 SAM-dependent methyltransferase -
  CA922_RS14985 - 3291688..3292182 (+) 495 WP_011216699.1 6-carboxytetrahydropterin synthase -
  CA922_RS14990 priA 3292183..3294360 (+) 2178 WP_042754571.1 primosomal protein N' Machinery gene
  CA922_RS14995 - 3294357..3294749 (+) 393 WP_015961865.1 thioesterase family protein -
  CA922_RS15000 - 3294867..3295136 (-) 270 WP_013102003.1 hypothetical protein -
  CA922_RS15005 thyA 3295212..3296006 (-) 795 WP_011947748.1 thymidylate synthase -
  CA922_RS15010 lgt 3296003..3296773 (-) 771 WP_027226129.1 prolipoprotein diacylglyceryl transferase -
  CA922_RS15015 - 3296791..3297597 (-) 807 WP_027226128.1 sulfite exporter TauE/SafE family protein -

Sequence

Protein


Download         Length: 725 a.a.        Molecular weight: 81629.04 Da        Isoelectric Point: 9.2815

>NTDB_id=191982 CA922_RS14990 WP_042754571.1 3292183..3294360(+) (priA) [Legionella pneumophila subsp. pneumophila strain Birmingham]
MNDIYQVCIPHTNRDCFDYEALDLTPCIGGRVWVPFRNQARVGIVINKVCGQQTGHSLKKITSIIDEKPMVPEDLLELCL
WVGSYYQSPLSEVIPLVIPKKYRLGLPCSLPTEDFYQLNIPVEKAKTLISKKAKKQHELIDFLSRHQKGISKQTLKQHGY
NGTQIATLLACQAINLSQQVTLPTKIPEKLSPPLTLNPEQAVAVSSILEHIHHYQCFLLQGVTGSGKTEVYLHVIAKILE
QGKQVLVLVPEIGLTPQLLSRFTARFNHPITVLHSNLNESERQIAWQLAKENKVKMVIGTRSAVFTPLPNLGLIIIDEEH
DSSLKQMEGVRYSARDTALMRAHLANIPIILGTATPSLETIHNCKQKKYTLLRLTHKAASTTPLHYQLIDLRSQMVQHGL
ALPTLKIIENHLLQQNQVLVFINRRGFAPVLLCHQCGWMVDCKACDSHLTLHKQAGQMICHHCGLTQRIPLFCNNCQSKE
LIPVGSGTQRIYEFLSHQFPDTNVLRIDRDEVRKKNSLNSHLDKINKGEAQLIIGTQMLAKGHHFPRLSLVVVVDADAGF
YNQDFRAIEHLGQLLTQVSGRAGRAEHPGQVLIQTYLPDHPLLNLLIQHGYDEFANALLISRQEAEMPPFQFLAVIRAQG
KTVNKVDQFLKATKDQIQAHPLTVLGPAPAPLPRKANQHRMQLLIKSPSRKVLKSSLTQLREWLTMNKLSNGIRWNVDVD
PMDLS

Nucleotide


Download         Length: 2178 bp        

>NTDB_id=191982 CA922_RS14990 WP_042754571.1 3292183..3294360(+) (priA) [Legionella pneumophila subsp. pneumophila strain Birmingham]
ATGAACGATATTTATCAAGTTTGTATCCCCCATACCAATCGAGATTGTTTTGATTACGAAGCCCTGGATTTAACTCCATG
CATTGGTGGAAGAGTATGGGTTCCTTTTCGCAATCAAGCCCGAGTGGGCATTGTGATCAATAAAGTTTGTGGCCAGCAAA
CGGGCCATTCGTTAAAGAAAATCACTTCAATAATCGATGAGAAACCTATGGTTCCTGAAGATCTCTTAGAGCTTTGTCTA
TGGGTAGGAAGTTATTATCAGTCACCATTATCTGAAGTGATTCCTTTGGTAATACCCAAAAAATATCGCCTGGGTTTGCC
TTGCTCACTACCTACAGAAGATTTTTATCAATTGAATATCCCTGTTGAAAAGGCGAAGACACTCATCTCGAAAAAAGCAA
AAAAACAACATGAATTGATTGATTTTTTAAGCAGACACCAGAAAGGAATTTCCAAACAGACCCTAAAACAACATGGCTAC
AACGGAACTCAAATTGCGACACTACTTGCTTGTCAAGCCATTAACTTGTCACAGCAAGTTACCTTGCCAACCAAAATTCC
TGAAAAACTCAGTCCACCGTTAACACTCAATCCTGAACAAGCCGTTGCCGTATCTTCCATTTTAGAACACATCCATCATT
ACCAATGCTTTTTACTGCAAGGTGTTACCGGAAGTGGTAAGACAGAGGTTTATTTGCATGTCATTGCCAAAATATTGGAG
CAAGGCAAACAAGTATTGGTGCTGGTACCAGAAATCGGGTTAACCCCTCAGCTTTTATCTCGTTTTACAGCCCGATTTAA
CCATCCCATAACCGTATTACATTCCAATTTGAATGAATCAGAAAGGCAAATTGCTTGGCAGCTGGCAAAAGAGAACAAAG
TTAAAATGGTGATTGGAACTCGTTCTGCCGTTTTTACCCCTCTGCCCAATCTCGGTTTAATTATCATCGATGAAGAGCAT
GACAGTTCGCTCAAACAAATGGAAGGGGTGCGTTATTCTGCGCGAGATACTGCTTTAATGCGTGCTCATCTTGCCAATAT
TCCTATCATTCTTGGTACAGCCACTCCCAGTCTGGAAACTATCCACAACTGCAAACAAAAAAAATATACTTTATTACGCT
TAACGCATAAAGCTGCCTCCACTACACCATTACACTATCAACTGATTGATTTAAGATCGCAAATGGTACAGCATGGCTTG
GCTCTCCCAACCCTTAAAATCATAGAAAATCATTTGCTGCAACAAAACCAGGTTCTTGTTTTCATTAACCGACGCGGCTT
TGCCCCAGTGTTACTTTGCCATCAATGTGGATGGATGGTTGATTGCAAAGCATGCGATAGCCATTTAACCTTGCATAAAC
AGGCAGGACAAATGATTTGTCATCATTGCGGATTAACCCAAAGAATACCTTTGTTTTGCAATAACTGCCAAAGCAAAGAA
TTAATCCCCGTAGGATCTGGCACCCAGAGAATTTATGAGTTTTTAAGCCATCAGTTTCCAGATACAAATGTTTTACGAAT
TGACCGAGATGAGGTTCGTAAAAAAAATTCTCTAAACAGCCATTTGGACAAAATTAATAAAGGGGAAGCTCAGCTGATCA
TAGGCACTCAAATGCTAGCCAAGGGACACCATTTCCCCCGCCTATCCCTGGTCGTTGTCGTAGATGCTGATGCAGGCTTT
TACAACCAGGATTTCCGGGCTATTGAACATTTGGGGCAATTATTAACTCAAGTATCTGGACGAGCTGGGCGAGCAGAACA
TCCCGGACAAGTATTGATTCAAACTTATTTACCTGATCATCCCCTGCTTAATCTACTCATTCAGCATGGGTATGATGAAT
TTGCAAACGCTTTATTAATTTCAAGACAAGAGGCTGAAATGCCCCCTTTTCAGTTTTTAGCGGTCATCAGAGCTCAGGGC
AAAACCGTCAACAAGGTGGATCAATTCCTAAAAGCAACCAAAGATCAAATTCAGGCTCATCCTCTCACGGTACTGGGTCC
TGCGCCAGCTCCTTTGCCACGAAAAGCTAACCAGCATAGGATGCAACTATTAATTAAATCCCCTTCAAGAAAAGTTCTAA
AAAGTTCATTGACGCAATTAAGAGAGTGGTTGACAATGAACAAATTAAGTAATGGCATCCGCTGGAATGTGGATGTTGAT
CCTATGGACTTATCATGA

Domains

Predicted by InterProScan.

PriA DNA helicase Cys-rich region (CRR) domain (Zn_ribbon_PriA)

(442-468)

Primosomal protein N C-terminal domain (PriA_C)

(629-721)

3DNA-binding domain (3BD) (PriA_3primeBD)

(6-99)

Type III restriction enzyme, res subunit (ResIII)

(195-357)

Helicase conserved C-terminal domain (Helicase_C)

(489-585)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  priA Acinetobacter baumannii D1279779

42.49

100

0.433

Multiple sequence alignment