Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6L95_RS02495 Genome accession   NZ_CP016677
Coordinates   456266..459355 (-) Length   1029 a.a.
NCBI ID   WP_079870587.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M25456     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 451266..464355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L95_RS13220 - 451829..451996 (-) 168 WP_153312129.1 hypothetical protein -
  A6L95_RS02465 (A6L95_02465) - 452000..452389 (-) 390 WP_002221514.1 endonuclease domain-containing protein -
  A6L95_RS02480 (A6L95_02480) - 452969..453106 (-) 138 WP_002214606.1 VOC family protein -
  A6L95_RS02485 (A6L95_02485) carA 453152..454285 (-) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A6L95_RS02495 (A6L95_02495) pilC 456266..459355 (-) 3090 WP_079870587.1 PilC family type IV pilus tip adhesin Machinery gene
  A6L95_RS02500 (A6L95_02500) apbC 459884..460963 (-) 1080 WP_002259079.1 iron-sulfur cluster carrier protein ApbC -
  A6L95_RS02510 (A6L95_02510) - 461328..461837 (+) 510 WP_002259078.1 protein disulfide oxidoreductase -
  A6L95_RS02520 (A6L95_02520) nadR 462180..462620 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  A6L95_RS02525 (A6L95_02525) hpaC 462735..463235 (+) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  A6L95_RS02530 (A6L95_02530) murU 463253..463948 (+) 696 WP_002221505.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -

Sequence

Protein


Download         Length: 1029 a.a.        Molecular weight: 112976.45 Da        Isoelectric Point: 9.8184

>NTDB_id=191470 A6L95_RS02495 WP_079870587.1 456266..459355(-) (pilC) [Neisseria meningitidis strain M25456]
MNKTLKRQVFRHTALYAAILMFSHTGGGGAQAETRNYAIVMNEQNQPNVKQEGSYSTLREKDRKRKFDFNANRGGGGSVF
FDNTDTLVSQQRGTAVFGTATYLPPYGKVSGFDEKRLTERGNALNWINTTHPGLIGYSYAGVVCRDSTSCPKLVYKTRFS
FDNTGLAKNAGSLDRHPDPSRENSPIYKLKDHPWLGVSFNLGSENTVKNGNSFNKLISSFSEDNNNQTIVSTTEGSPISL
GDQQREHTAVVYYLNAKLHLLDKKQIQNITDKTVQLGTLRPRVETTGRSWLNFWATWKIEDKGNITVRLDLPEVKAGRCV
NANNPNKSTKAPSPALTAPALWFGPVQNGKAEMYSASVSTYPDSSSSRIFLQNLKRKNDSNRPGRHSLETLTENDIKSRQ
PNFTGRQTIIRLDSGVQQIKLQGNEVANFNRNDGKNDTFGIVSEYGLTPDANEWKKVLLPWTVRAFNDDGRFNTVNKEEN
NGKPKYSQRYRIRENGNNGNNGKRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRKDIQ
NTESTLAKELRAFAEKSYVGDRYGVDGGFVLRQVELSGKKHVFMFGAMGFGGRGAYALDLTKAENGNPTAVSLFDVKHDN
NGKNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKTIDSTDNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLV
DKDLDGIVDIAYAGDRGGNMYRFDLSGNNPNSWTVRPIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDNKDIQH
VYGIFDNDTDTGTAQDGQGKGLLEQVLSEENKTLFLTDYKRSNGSGSKGWMVKLQPRQRVTVKPTVVLRTAFVTIRKYED
NGCGAETAILGINTADGGKLTKKSARPIVPAANQAVAQYSGHKQTTKGKSIPIGCMQKGNEIVCPNGYVYDKPVNVRYLD
EKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3090 bp        

>NTDB_id=191470 A6L95_RS02495 WP_079870587.1 456266..459355(-) (pilC) [Neisseria meningitidis strain M25456]
ATGAATAAAACTTTAAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGCAGGCGGAAACCCGTAACTACGCTATTGTCATGAACGAACAAAATCAGCCGAATGTAAAGCAGGAGGGTT
CATATTCAACCTTAAGGGAAAAAGACAGGAAACGCAAATTTGACTTTAATGCGAACAGAGGGGGTGGAGGTTCTGTCTTT
TTCGACAATACCGATACCCTTGTTTCCCAACAAAGAGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGAAAAGAGGCTGACAGAGCGCGGCAATGCCCTTAATTGGATTAATACGACCCACCCAGGGT
TGATAGGCTACAGCTACGCCGGTGTCGTATGCAGAGACAGCACAAGCTGTCCCAAACTTGTCTATAAAACCCGATTTTCC
TTCGACAACACCGGTTTGGCAAAAAATGCGGGCAGCCTGGATAGGCACCCGGACCCAAGCCGCGAAAATTCGCCCATTTA
CAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATGGCAACTCATTCA
ACAAATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAGGCTCCCCTATTTCCCTT
GGCGACCAGCAGCGCGAACATACCGCCGTGGTCTATTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAAACAGATTCA
AAATATCACCGACAAAACAGTGCAGTTGGGCACCTTGAGACCGCGCGTCGAGACGACAGGACGAAGCTGGCTAAATTTTT
GGGCTACGTGGAAGATTGAAGATAAAGGGAACATTACAGTCCGCCTCGACCTGCCGGAAGTCAAAGCAGGCCGCTGCGTC
AACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCCCCGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCA
AAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCATCTTCCTTCAAAATC
TGAAAAGAAAAAACGACTCCAACAGACCCGGCCGCCATTCCCTCGAAACCTTGACTGAGAACGATATTAAAAGTCGACAG
CCGAATTTCACAGGGCGGCAAACAATCATCCGATTGGATAGCGGCGTACAGCAGATCAAACTTCAAGGCAATGAGGTCGC
CAATTTTAATAGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAGTGAATATGGCCTCACGCCTGATGCCAATGAGT
GGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTAACACAGTCAACAAAGAAGAAAAC
AACGGCAAGCCAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAACGGCAACAACGGCAAGCGTGATTTGGG
CGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCA
AACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGCAAGGATATTCAA
AACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAAGCTATGTGGGCGACCGCTACGGCGTGGACGG
CGGCTTTGTTTTGCGCCAAGTCGAACTGAGCGGGAAAAAACACGTGTTTATGTTCGGCGCGATGGGTTTTGGCGGCAGAG
GCGCATACGCCTTGGATTTGACCAAAGCCGAAAACGGTAACCCGACCGCCGTTTCCCTGTTTGATGTCAAACATGACAAT
AATGGCAAGAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACAACGGCAA
ATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACAGCACAGACAATAAAACCGCGCTGTATGTGTATG
ATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTG
GATAAAGATTTGGACGGCATTGTTGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGATTTAAGCGG
CAACAACCCGAACAGTTGGACTGTACGCCCTATTTTTGAAGGCACAAAACCGATTACTTCCGCGCCCGCCATTTCCCAAC
TGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAGGATGATGTGGACAACAAAGACATCCAACAC
GTTTACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAAAGGGCTGCTCGAGCAAGTGCT
TAGTGAGGAAAATAAAACCTTATTCCTGACCGATTACAAGCGATCCAACGGATCGGGCAGTAAGGGGTGGATGGTGAAAT
TGCAGCCCAGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAATATGAAGAC
AACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCC
GATTGTGCCGGCAGCCAATCAGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCACCAAAGGCAAATCCATCCCTATAG
GTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGAC
GAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTC
CGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCG
GCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(506-837)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

81.13

100

0.823

Multiple sequence alignment