Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6L20_RS10395 Genome accession   NZ_CP016675
Coordinates   1991545..1994640 (-) Length   1031 a.a.
NCBI ID   WP_079870438.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M07161     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1986545..1999640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L20_RS13760 - 1987108..1987275 (-) 168 WP_153312129.1 hypothetical protein -
  A6L20_RS10365 (A6L20_10365) - 1987279..1987668 (-) 390 WP_002221514.1 endonuclease domain-containing protein -
  A6L20_RS10380 (A6L20_10380) - 1988248..1988385 (-) 138 WP_002214606.1 VOC family protein -
  A6L20_RS10385 (A6L20_10385) carA 1988431..1989564 (-) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A6L20_RS10395 (A6L20_10395) pilC 1991545..1994640 (-) 3096 WP_079870438.1 PilC family type IV pilus tip adhesin Machinery gene
  A6L20_RS10400 (A6L20_10400) apbC 1995579..1996658 (-) 1080 WP_002248347.1 iron-sulfur cluster carrier protein ApbC -
  A6L20_RS10410 (A6L20_10410) - 1997023..1997532 (+) 510 WP_002225670.1 protein disulfide oxidoreductase -
  A6L20_RS10420 (A6L20_10420) nadR 1997875..1998315 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  A6L20_RS10425 (A6L20_10425) hpaC 1998430..1998930 (+) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1031 a.a.        Molecular weight: 113055.57 Da        Isoelectric Point: 9.8243

>NTDB_id=191409 A6L20_RS10395 WP_079870438.1 1991545..1994640(-) (pilC) [Neisseria meningitidis strain M07161]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGGAMAQTHKYAIIMNEGNQPEVKQNGQYSTIKDKDREREYTYHQGTRGGGS
VSFNNSDELVSRQSGTAVFGTATYLPPYGKVSGFDEKRLTERGNALNWINTTHPGLIGYSYAGVVCRDSTSCPKLVYKTR
FSFDNTGLAKNAGSLDRHPDPSRENSPIYKLKDHPWLGVSFNLGSENTVKNGNSFNKLISSFSEDNNNQTIVSTTEGSPI
SLGDQQREHTAVVYYLNAKLHLLDKKQIQNITDKTVQLGTLRPRVETTGRSWLNFWATWKIEDKGNITVRLDLPEVKAGR
CVNANNPNKSTKAPSPALTAPALWFGPVQNGKAEMYSASVSTYPDSSSSRIFLQNLKRKNDSNRPGRHSLETLTENDIKS
RQPNFTGRQTIIRLDSGVQQIKLQGNEVANFNRNDGKNDTFGIVSEYGLTPDANEWKKVLLPWTVRAFNDDGRFNTVNKE
ENNGKPKYSQRYRIRENGNNGNNGKRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRKD
IQNTESTLAKELRAFAEKSYVGDRYGVDGGFVLRQVELSGKKHVFMFGAMGFGGRGAYALDLTKAENGNPTAVSLFDVKH
DNNGKNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKTIDSTDNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPT
LVDKDLDGIVDIAYAGDRGGNMYRFDLSGNNPNSWTVRPIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDNKDI
QHVYGIFDNDTDTGTAQDGQGKGLLEQVLSEENKTLFLTDYKRSNGSGSKGWMVKLQPRQRVTVKPTVVLRTAFVTIRKY
KDNGCGAETAILGINTADGGKLTKKSARPIVPAANQAVAQYSGHKQTTKGKSIPIGCMQKGNEIVCPNGYVYDKPVNVRY
LDEKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3096 bp        

>NTDB_id=191409 A6L20_RS10395 WP_079870438.1 1991545..1994640(-) (pilC) [Neisseria meningitidis strain M07161]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGGGGCGATGGCGCAAACCCATAAATACGCTATTATCATGAACGAGGGAAACCAGCCCGAGGTAAAGCAGA
ATGGGCAATATTCAACAATAAAGGACAAAGACAGGGAGCGCGAATATACTTATCATCAGGGCACAAGAGGAGGAGGCTCT
GTCTCATTCAACAATAGCGATGAGCTTGTTTCTCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCC
CTACGGCAAGGTTTCCGGTTTTGATGAAAAGAGGCTGACAGAGCGCGGCAATGCCCTTAATTGGATTAATACGACCCACC
CAGGGTTGATAGGCTACAGCTACGCCGGTGTCGTATGCAGAGACAGCACAAGCTGTCCCAAACTTGTCTATAAAACCCGA
TTTTCCTTCGACAACACCGGTTTGGCAAAAAATGCGGGCAGCCTGGATAGGCACCCGGACCCAAGCCGCGAAAATTCGCC
CATTTACAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATGGCAACT
CATTCAACAAATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAGGCTCCCCTATT
TCCCTTGGCGACCAGCAGCGCGAACATACCGCCGTGGTCTATTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAAACA
GATTCAAAATATCACCGACAAAACAGTGCAGTTGGGCACCTTGAGACCGCGCGTCGAGACGACAGGACGAAGCTGGCTAA
ATTTTTGGGCTACGTGGAAGATTGAAGATAAAGGGAACATTACAGTCCGCCTCGACCTGCCGGAAGTCAAAGCAGGCCGC
TGCGTCAACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCCCCGCACTGACCGCCCCCGCGCTGTGGTTCGGCCC
TGTGCAAAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCATCTTCCTTC
AAAATCTGAAAAGAAAAAACGACTCCAACAGACCCGGCCGCCATTCCCTCGAAACCTTGACTGAGAACGATATTAAAAGT
CGACAGCCGAATTTCACAGGGCGGCAAACAATCATCCGATTGGATAGCGGCGTACAGCAGATCAAACTTCAAGGCAATGA
GGTCGCCAATTTTAATAGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAGTGAATATGGCCTCACGCCTGATGCCA
ATGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTAACACAGTCAACAAAGAA
GAAAACAACGGCAAGCCAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAACGGCAACAACGGCAAGCGTGA
TTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATA
TCTTCAAACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGCAAGGAT
ATTCAAAACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAAGCTATGTGGGCGACCGCTACGGCGT
GGACGGCGGCTTTGTTTTGCGCCAAGTCGAACTGAGCGGGAAAAAACACGTGTTTATGTTCGGCGCGATGGGTTTTGGCG
GCAGAGGCGCATACGCCTTGGATTTGACCAAAGCCGAAAACGGTAACCCGACCGCCGTTTCCCTGTTTGATGTCAAACAT
GACAATAATGGCAAGAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACAA
CGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACAGCACAGACAATAAAACCGCGCTGTATG
TGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACG
CTGGTGGATAAAGATTTGGACGGCATTGTTGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGATTT
AAGCGGCAACAACCCGAACAGTTGGACTGTACGCCCTATTTTTGAAGGCACAAAACCGATTACTTCCGCGCCCGCCATTT
CCCAACTGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAGGATGATGTGGACAACAAAGACATC
CAACACGTTTACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAAAGGGCTGCTCGAGCA
AGTGCTTAGTGAGGAAAATAAAACCTTATTCCTGACCGATTACAAGCGATCCAACGGATCGGGCAGTAAGGGGTGGATGG
TGAAATTGCAGCCCAGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAATAT
AAAGACAACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGC
GCGCCCGATTGTGCCGGCAGCCAATCAGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCACCAAAGGCAAATCCATCC
CTATAGGTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTAC
CTGGACGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAA
GCGTTCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACA
TTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(508-839)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

81.071

100

0.823

Multiple sequence alignment