Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   A6L46_RS10365 Genome accession   NZ_CP016660
Coordinates   1975953..1976651 (+) Length   232 a.a.
NCBI ID   WP_002224844.1    Uniprot ID   Q9K189
Organism   Neisseria meningitidis strain M22804     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1970953..1981651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L46_RS10350 (A6L46_10350) trpC 1972034..1972816 (-) 783 WP_002234509.1 indole-3-glycerol phosphate synthase TrpC -
  A6L46_RS10355 (A6L46_10355) - 1972867..1973823 (-) 957 WP_002234510.1 YheT family hydrolase -
  A6L46_RS10360 (A6L46_10360) murJ 1973956..1975494 (-) 1539 WP_002226012.1 murein biosynthesis integral membrane protein MurJ -
  A6L46_RS14930 - 1975552..1975659 (+) 108 Protein_1913 IS5/IS1182 family transposase -
  A6L46_RS10365 (A6L46_10365) dsbA1 1975953..1976651 (+) 699 WP_002224844.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  A6L46_RS10370 (A6L46_10370) amgK 1976708..1977712 (-) 1005 WP_002221582.1 N-acetylmuramate/N-acetylglucosamine kinase AmgK -
  A6L46_RS10375 (A6L46_10375) - 1977782..1980190 (+) 2409 WP_002240242.1 LPS-assembly protein LptD -
  A6L46_RS10380 (A6L46_10380) - 1980292..1981320 (+) 1029 WP_079255465.1 peptidylprolyl isomerase -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 25249.83 Da        Isoelectric Point: 5.6277

>NTDB_id=190708 A6L46_RS10365 WP_002224844.1 1975953..1976651(+) (dsbA1) [Neisseria meningitidis strain M22804]
MKSRHLALGVAALFALAACDSKVQTSVPADSAPAASAAAAPAGLVEGQNYTVLANPIPQQQAGKVEVLEFFGYFCPHCAH
LEPVLSKHAKSFKDDMYLRTEHVVWQKEMLTLARLAAAVDMAAADSKDVANSHIFDAMVNQKIKLQNPEVLKKWLGEQTA
FDGKKVLAAYESPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMNTIDLLADKVREEQKAAQ

Nucleotide


Download         Length: 699 bp        

>NTDB_id=190708 A6L46_RS10365 WP_002224844.1 1975953..1976651(+) (dsbA1) [Neisseria meningitidis strain M22804]
ATGAAATCCAGACACCTCGCCCTCGGCGTTGCCGCCCTGTTCGCCCTTGCCGCGTGCGACAGCAAAGTCCAAACCAGCGT
CCCCGCCGACAGCGCGCCTGCCGCTTCGGCAGCCGCCGCCCCGGCAGGGCTGGTCGAAGGGCAAAACTATACCGTCCTTG
CCAACCCGATTCCCCAACAGCAGGCAGGCAAAGTCGAAGTCCTTGAGTTTTTCGGCTATTTTTGTCCGCACTGCGCCCAC
CTCGAACCTGTTTTAAGCAAACACGCCAAGTCTTTTAAAGACGATATGTACCTGCGTACCGAACACGTCGTCTGGCAGAA
AGAAATGCTGACGCTGGCACGCCTCGCCGCCGCCGTCGATATGGCTGCCGCCGACAGCAAAGATGTGGCGAACAGCCATA
TTTTCGATGCGATGGTCAACCAAAAAATCAAGCTGCAAAATCCGGAAGTCCTCAAAAAATGGCTGGGCGAACAAACCGCC
TTTGACGGCAAAAAAGTCCTTGCCGCCTACGAGTCCCCCGAAAGCCAGGCGCGCGCCGACAAAATGCAGGAGCTGACCGA
AACCTTCCAAATCGACGGTACGCCCACGGTTATCGTCGGCGGTAAATATAAAGTTGAATTTGCCGACTGGGAGTCCGGTA
TGAACACCATCGACCTTTTGGCGGACAAAGTACGCGAAGAACAAAAAGCCGCGCAGTAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(63-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3A3T
  PDB 3DVW
  PDB 3HZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

100

100

1
  dsbA2 Neisseria meningitidis MC58

76.19

81.466

0.621

Multiple sequence alignment