Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CAH07_RS18465 Genome accession   NZ_CP021123
Coordinates   3546414..3547055 (-) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain SEM-9     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3541414..3552055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CAH07_RS18450 (CAH07_18270) ydfK 3541917..3542606 (+) 690 WP_019712443.1 DUF554 domain-containing protein -
  CAH07_RS18455 (CAH07_18275) cesA 3542809..3543711 (+) 903 WP_029725828.1 carboxylesterase -
  CAH07_RS18460 (CAH07_18280) pleJ 3544124..3546298 (-) 2175 WP_129010121.1 MMPL family transporter -
  CAH07_RS18465 (CAH07_18285) vraR 3546414..3547055 (-) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  CAH07_RS18470 (CAH07_18290) ydfH 3547048..3548271 (-) 1224 WP_015252722.1 two-component system sensor histidine kinase YdfH -
  CAH07_RS18475 (CAH07_18295) - 3548538..3548681 (+) 144 WP_003243880.1 hypothetical protein -
  CAH07_RS18480 (CAH07_18300) - 3548678..3548857 (+) 180 WP_106074101.1 hypothetical protein -
  CAH07_RS18485 (CAH07_18305) ydfG 3548943..3549386 (+) 444 WP_128422112.1 carboxymuconolactone decarboxylase family protein -
  CAH07_RS18490 (CAH07_18310) ydfF 3549451..3550131 (-) 681 WP_014478969.1 winged helix-turn-helix domain-containing protein -
  CAH07_RS18495 (CAH07_18315) ydfE 3550221..3550844 (+) 624 WP_029317354.1 flavin reductase family protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=190598 CAH07_RS18465 WP_003244318.1 3546414..3547055(-) (vraR) [Bacillus subtilis strain SEM-9]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=190598 CAH07_RS18465 WP_003244318.1 3546414..3547055(-) (vraR) [Bacillus subtilis strain SEM-9]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTCGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAGGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCGATCAGAGGAAATGTGCTATTGCAGCCTGATATCCTCAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCAAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362

Multiple sequence alignment