Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6L61_RS03445 Genome accession   NZ_CP016658
Coordinates   639191..642280 (+) Length   1029 a.a.
NCBI ID   WP_079870521.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M24730     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 634191..647280
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L61_RS03410 (A6L61_03410) murU 634598..635293 (-) 696 WP_002221505.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -
  A6L61_RS03415 (A6L61_03415) hpaC 635311..635811 (-) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  A6L61_RS03420 (A6L61_03420) nadR 635926..636366 (-) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  A6L61_RS03430 (A6L61_03430) - 636709..637218 (-) 510 WP_002259078.1 protein disulfide oxidoreductase -
  A6L61_RS03440 (A6L61_03440) apbC 637583..638662 (+) 1080 WP_002259079.1 iron-sulfur cluster carrier protein ApbC -
  A6L61_RS03445 (A6L61_03445) pilC 639191..642280 (+) 3090 WP_079870521.1 PilC family type IV pilus tip adhesin Machinery gene
  A6L61_RS03455 (A6L61_03455) carA 644213..645346 (+) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A6L61_RS03460 (A6L61_03460) - 645392..645529 (+) 138 WP_002214606.1 VOC family protein -
  A6L61_RS03475 (A6L61_03475) - 646109..646498 (+) 390 WP_002221514.1 endonuclease domain-containing protein -
  A6L61_RS13420 - 646502..646669 (+) 168 WP_153312129.1 hypothetical protein -

Sequence

Protein


Download         Length: 1029 a.a.        Molecular weight: 113024.54 Da        Isoelectric Point: 9.8430

>NTDB_id=190594 A6L61_RS03445 WP_079870521.1 639191..642280(+) (pilC) [Neisseria meningitidis strain M24730]
MNKTLKRQVFRHTALYAAILMFSHTGGGGAQAETRNYAIVMNEQNQPKVKQEGSYSTLREKDRKRKFDFNANRGGGGSVF
FDNTDTLVSQQRGTAVFGTATYLPPYGKVSGFDEKRLTERGNALNWINTTHPGLIGYSYAGVVCRDSTSCPKLVYKTRFS
FDNTGLAKNAGSLDRHPDPSRENSPIYKLKDHPWLGVSFNLGSENTVKNGNSFNKLISSFSEDNNNQTIVSTTEGSPISL
GDQQREHTAVVYYLNAKLHLLDKKQIQNITDKTVQLGTLRPRVETTGRSWLNFWATWKIEDKGNITVRLDLPEVKAGRCV
NANNPNKSTKAPSPALTAPALWFGPVQNGKAEMYSASVSTYPDSSSSRIFFQNLKRKNDSNRPGRHSLETLTENDIKSRQ
PNFTGRQTIIRLDSGVQQIKLQGNEVANFNRNDGKNDTFGIVSEYGLTPDANEWKKVLLPWTVRAFNDDGRFNTVNKEEN
NGKPKYSQRYRIRENGNNGNNGKRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRKDIQ
NTESTLAKELRAFAEKSYVGDRYGVDGGFVLRQVELSGKKHVFMFGAMGFGGRGAYALDLTKAENGNPTAVSLFDVKHDN
NGKNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKTIDSTDNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLV
DKDLDGIVDIAYAGDRGGNMYRFDLSGNNPNSWTVRPIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDNKDIQH
VYGIFDNDTDTGTAQDGQGKGLLEQVLSEENKTLFLTDYKRSNGSGSKGWMVKLQPRQRVTVKPTVVLRTAFVTIRKYED
NGCGAETAILGINTADGGKLTKKSARPIVPAANQAVAQYSGHKQTTKGKSIPIGCMQKGNEIVCPNGYVYDKPVNVRYLD
EKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3090 bp        

>NTDB_id=190594 A6L61_RS03445 WP_079870521.1 639191..642280(+) (pilC) [Neisseria meningitidis strain M24730]
ATGAATAAAACTTTAAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGCAGGCGGAAACCCGTAACTACGCTATTGTCATGAACGAACAAAATCAGCCGAAGGTAAAGCAGGAGGGTT
CATATTCAACCTTAAGGGAAAAAGACAGGAAACGCAAATTTGACTTTAATGCGAACAGAGGGGGTGGAGGTTCTGTCTTT
TTCGACAATACCGATACCCTTGTTTCCCAACAAAGAGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGAAAAGAGGCTGACAGAGCGCGGCAATGCCCTTAATTGGATTAATACGACCCACCCAGGGT
TGATAGGCTACAGCTACGCCGGTGTCGTATGCAGAGACAGCACAAGCTGTCCCAAACTTGTCTATAAAACCCGATTTTCC
TTCGACAACACCGGTTTGGCAAAAAATGCGGGCAGCCTGGATAGGCACCCGGACCCAAGCCGCGAAAATTCGCCCATTTA
CAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATGGCAACTCATTCA
ACAAATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAGGCTCCCCTATTTCCCTT
GGCGACCAGCAGCGCGAACATACCGCCGTGGTCTATTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAAACAGATTCA
AAATATCACCGACAAAACAGTGCAGTTGGGCACCTTGAGACCGCGCGTCGAGACGACAGGACGAAGCTGGCTAAATTTTT
GGGCTACGTGGAAGATTGAAGATAAAGGGAACATTACAGTCCGCCTCGACCTGCCGGAAGTCAAAGCAGGCCGCTGCGTC
AACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCCCCGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCA
AAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCATCTTCTTTCAAAATC
TGAAAAGAAAAAACGACTCCAACAGACCCGGCCGCCATTCCCTCGAAACCTTGACTGAGAACGATATTAAAAGTCGACAG
CCGAATTTCACAGGGCGGCAAACAATCATCCGATTGGATAGCGGCGTACAGCAGATCAAACTTCAAGGCAATGAGGTCGC
CAATTTTAATAGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAGTGAATATGGCCTCACGCCTGATGCCAATGAGT
GGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTAACACAGTCAACAAAGAAGAAAAC
AACGGCAAGCCAAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAACGGCAACAACGGCAAGCGTGATTTGGG
CGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCA
AACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGCAAGGATATTCAA
AACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAAGCTATGTGGGCGACCGCTACGGCGTGGACGG
CGGCTTTGTTTTGCGCCAAGTCGAACTGAGCGGGAAAAAACACGTGTTTATGTTCGGCGCGATGGGTTTTGGCGGCAGAG
GCGCATACGCCTTGGATTTGACCAAAGCCGAAAACGGTAACCCGACCGCCGTTTCCCTGTTTGATGTCAAACATGACAAT
AATGGCAAGAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACAACGGCAA
ATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACAGCACAGACAATAAAACCGCGCTGTATGTGTATG
ATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTG
GATAAAGATTTGGACGGCATTGTTGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGATTTAAGCGG
CAACAACCCGAACAGTTGGACTGTACGCCCTATTTTTGAAGGCACAAAACCGATTACTTCCGCGCCCGCCATTTCCCAAC
TGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAGGATGATGTGGACAACAAAGACATCCAACAC
GTTTACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAAAGGGCTGCTCGAGCAAGTGCT
TAGTGAGGAAAATAAAACCTTATTCCTGACCGATTACAAGCGATCCAACGGATCGGGCAGTAAGGGGTGGATGGTGAAAT
TGCAGCCCAGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAATATGAAGAC
AACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCC
GATTGTGCCGGCAGCCAATCAGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCACCAAAGGCAAATCCATCCCTATAG
GTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGAC
GAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTC
CGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCG
GCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(506-837)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

81.034

100

0.822

Multiple sequence alignment