Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6L30_RS08520 Genome accession   NZ_CP016649
Coordinates   1650980..1654069 (-) Length   1029 a.a.
NCBI ID   WP_079884494.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22189     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1645980..1659069
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L30_RS13650 - 1646746..1646913 (-) 168 WP_153312129.1 hypothetical protein -
  A6L30_RS08485 (A6L30_08485) - 1646917..1647306 (-) 390 WP_002221514.1 endonuclease domain-containing protein -
  A6L30_RS08500 (A6L30_08500) - 1647886..1648023 (-) 138 WP_002214606.1 VOC family protein -
  A6L30_RS08505 (A6L30_08505) carA 1648069..1649202 (-) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A6L30_RS08520 (A6L30_08520) pilC 1650980..1654069 (-) 3090 WP_079884494.1 PilC family type IV pilus tip adhesin Machinery gene
  A6L30_RS08525 (A6L30_08525) apbC 1655625..1656704 (-) 1080 WP_065821474.1 iron-sulfur cluster carrier protein ApbC -
  A6L30_RS08535 (A6L30_08535) - 1657069..1657578 (+) 510 WP_002240006.1 protein disulfide oxidoreductase -
  A6L30_RS08545 (A6L30_08545) nadR 1657921..1658361 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  A6L30_RS08550 (A6L30_08550) hpaC 1658476..1658976 (+) 501 WP_002233027.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1029 a.a.        Molecular weight: 112735.82 Da        Isoelectric Point: 9.9371

>NTDB_id=190182 A6L30_RS08520 WP_079884494.1 1650980..1654069(-) (pilC) [Neisseria meningitidis strain M22189]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAQAQTRQYAIIMNEGNQPEVQWNGSYSIKDKDRKREYTHHNHSRGGSSVSF
NNSDELVSQQSGTAVFGTATYLPPYGKVSGFDADGLNKRGNAAGWIRTTRIALAGYSYEGIVCRSGTGCPKLVYKTRFSF
DNPDLVKNAGRLDRHTDPSRENSPIYKLKDYPWLGVSFNLGAEGTTKDGKTINKLVSSFDEKNSSNNNLVYTTEGRDISL
GDWQREKTAMAYYLNAKLHLLDKKGIKDITNKTVQLGVLRPSIDVRLQRNTGLAGLLNFWASWDIKDNGQIPVKLGLPEV
KAGRCINANNPNKSTKAPSPALTAPALWFGPVQNGKMEMYSASVSTYPDSSSSRIFLQNLKRKNDPNKPGRYSLATLNKS
DIESREPTFTGRQTVIRLDKGVHQIKLKGNEVEGFKGNNGNDTFGIVSEGSFMPDDSEWKKVLLPWTVRGVNDDQFKTFN
KEEKNGKPKYSQKYRSRDNGKHERNLGDIVNSPIVAVGEYLATSANDGMVHIFKKGNGDARNYSLKLSYIPGTMPRKDIQ
NTESTLAKELRAFAEKGYVGDRYGVDGGFVLRQVELSGKKHVFMFGAMGFGGRGAYALDLTKAENGNPTAVSLFDVKHDN
NGKNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKTIDSTDNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLV
DKDLDGIVDIAYAGDRGGNMYRFDLSGNNPNSWTVRPIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDNKDIQH
VYGIFDNDTDTGTAQDGQGKGLLEQVLSEENKTLFLTDYKRSNGSGSKGWMVKLQPRQRVTVKPTVVLRTAFVTIRKYKD
NGCGAETAILGINTADGGKLTKKSARPIVPAANQAVAQYSGHKQTTKGKSIPIGCMQKGNEIVCPNGYVYDKPVNVRYLD
EKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3090 bp        

>NTDB_id=190182 A6L30_RS08520 WP_079884494.1 1650980..1654069(-) (pilC) [Neisseria meningitidis strain M22189]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGCAGGCGCAAACCCGTCAATACGCTATTATCATGAACGAGGGAAACCAGCCCGAGGTACAGTGGAATGGGT
CATATTCAATAAAGGACAAAGACAGGAAGCGCGAATATACTCATCATAATCACTCACGAGGAGGAAGCTCTGTCTCATTC
AACAATAGCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGGCAA
GGTTTCCGGTTTTGATGCCGACGGGCTGAACAAGCGCGGCAATGCCGCCGGTTGGATTCGTACCACCCGCATCGCGCTGG
CAGGCTACAGCTACGAAGGTATCGTATGCAGAAGCGGCACAGGCTGTCCCAAACTTGTCTATAAAACCCGATTTTCCTTC
GATAATCCCGACTTGGTAAAAAATGCGGGCAGGCTGGATAGGCACACAGACCCAAGCCGCGAAAATTCGCCCATTTACAA
ATTGAAGGATTATCCATGGTTGGGCGTATCTTTCAATTTGGGTGCCGAGGGTACCACCAAAGATGGTAAGACAATCAACA
AATTGGTATCTTCTTTTGATGAAAAGAATAGTAGTAATAACAACCTCGTCTATACCACGGAAGGCCGCGATATTTCCTTG
GGCGACTGGCAGCGCGAAAAGACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAGGGATTAA
AGATATCACCAACAAAACAGTGCAGTTGGGTGTCTTGAGGCCGAGCATCGATGTGCGGCTGCAAAGAAATACGGGGCTTG
CCGGCTTGCTAAATTTTTGGGCTAGTTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCGGAAGTC
AAAGCAGGCCGCTGCATCAACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCCCCGCACTGACTGCCCCCGCGCT
GTGGTTCGGACCTGTGCAAAATGGTAAGATGGAGATGTATTCCGCTTCGGTTTCTACCTACCCCGACAGTTCGAGCAGCC
GCATCTTCCTTCAAAATCTGAAAAGAAAAAACGACCCCAACAAACCCGGCCGCTATTCCCTCGCAACCTTGAATAAGTCG
GATATTGAAAGTCGAGAGCCGACTTTCACAGGGCGGCAAACCGTCATCCGATTGGATAAAGGCGTACATCAGATCAAACT
TAAAGGCAATGAGGTCGAAGGTTTTAAGGGAAACAACGGCAACGACACTTTCGGCATTGTTAGTGAAGGGAGCTTCATGC
CTGATGACAGCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTGTCAATGACGATCAATTTAAAACATTCAAC
AAAGAAGAAAAAAACGGCAAGCCAAAATACAGTCAAAAATACCGCAGCCGCGACAACGGCAAGCACGAGCGCAATTTGGG
CGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCA
AAAAAGGCAACGGGGACGCGCGCAACTATAGTCTGAAGCTCAGTTATATCCCGGGCACGATGCCGCGCAAGGATATTCAA
AACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGG
CGGCTTTGTTTTGCGCCAAGTCGAACTGAGCGGGAAAAAACACGTGTTTATGTTCGGCGCGATGGGTTTTGGCGGCAGAG
GCGCATACGCCTTGGATTTGACCAAAGCCGAAAACGGTAACCCGACCGCCGTTTCCCTGTTTGATGTCAAACATGACAAT
AATGGCAAGAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACAACGGCAA
ATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACAGCACAGACAATAAAACCGCGCTGTATGTGTATG
ATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTG
GATAAAGATTTGGACGGCATTGTTGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGATTTAAGCGG
CAACAACCCGAACAGTTGGACTGTACGCCCTATTTTTGAAGGCACAAAACCGATTACTTCCGCGCCCGCCATTTCCCAAC
TGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAGGATGATGTGGACAACAAAGACATCCAACAC
GTTTACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAAAGGGCTGCTCGAGCAAGTGCT
TAGTGAGGAAAATAAAACCTTATTCCTGACCGATTACAAGCGATCCAACGGATCGGGCAGTAAGGGGTGGATGGTGAAAT
TGCAGCCCAGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAATATAAAGAC
AACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCC
GATTGTGCCGGCAGCCAATCAGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCACCAAAGGCAAATCCATCCCTATAG
GTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGAC
GAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTC
CGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCG
GCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(506-837)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

77.321

100

0.785

Multiple sequence alignment