Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6L49_RS04885 Genome accession   NZ_CP016646
Coordinates   924134..927223 (-) Length   1029 a.a.
NCBI ID   WP_079883358.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22819     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 919134..932223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L49_RS04860 (A6L49_04860) - 920166..920555 (-) 390 WP_002240036.1 endonuclease domain-containing protein -
  A6L49_RS04870 (A6L49_04870) - 921116..921253 (-) 138 WP_002214606.1 VOC family protein -
  A6L49_RS04875 (A6L49_04875) carA 921299..922432 (-) 1134 WP_002258700.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A6L49_RS04885 (A6L49_04885) pilC 924134..927223 (-) 3090 WP_079883358.1 PilC family type IV pilus tip adhesin Machinery gene
  A6L49_RS04890 (A6L49_04890) apbC 928503..929582 (-) 1080 WP_002239302.1 iron-sulfur cluster carrier protein ApbC -
  A6L49_RS04900 (A6L49_04900) - 929947..930456 (+) 510 WP_002240006.1 protein disulfide oxidoreductase -
  A6L49_RS04910 (A6L49_04910) nadR 930799..931239 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  A6L49_RS04915 (A6L49_04915) hpaC 931354..931854 (+) 501 WP_002233027.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1029 a.a.        Molecular weight: 112669.34 Da        Isoelectric Point: 9.7717

>NTDB_id=190026 A6L49_RS04885 WP_079883358.1 924134..927223(-) (pilC) [Neisseria meningitidis strain M22819]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAQAQTRQYAIIMNEGNQPEVQWNGSYSIKDKDRKREYTHHNHSRGGSSVSF
NNSDELVSQQSGTAVFGTATYLPPYGKVSGFDADGLNKRGNAAGWIRTTRIALAGYSYEGIVCRSGTGCPKLVYKTRFSF
DNPDLVKNAGRLDRHTDPSRENSPIYKLKDYPWLGVSFNLGAEGTTKDGKTINKLVSSFDEKNSSNNNLVYTTEGRDISL
GDWQREKTAMAYYLNAKLHLLDKKGIKDITNKTVQLGVLRPSIDVRLQRNTGLAGLLNFWASWDIKDNGQIPVKLGLPEV
KAGRCINANNPNKSTKAPSPALTAPALWFGPVQNGKMEMYSASVSTYPDSSSSRIFLQNLKRKNDPNKPGRYSLATLNKS
DIESREPTFTGRQTVIRLDKGVHQIKLKGNEVEGFKGNNGNDTFGIVSEGSFMPDDSEWKKVLLPWTVRGVNDDQFKTFN
KEEKNGKPKYSQKYRSRDNGKHERNLGDIVNSPIVAVGEYLATSANDGMVHIFKKGNGDARNYSLKLSYIPGTMPRKDIQ
NTESTLAKELRAFAEKGYVGDRYGVDGGFVLRQVNNLNGQDRVFMFGAMGFGGRGAYALDLTKADSNNPTAVSLFDVKND
KNKGNNSAELGYTVGTPQIGKTHDGKYAAFLASGYATKTIDDQQNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLVD
KDLDGTVDIAYAGDRGGNMYRFDLSGQDPNQWSVRTIFSGNKPITSAPAISQLKDKRVVIFGTGSDLSEEDVDNNDIQSI
YGIFDNDTDTGTAQDGQGNGLLEQVLKKDGNTLFLSDYKRSNGSGDKGWVVKLEAGQRVTVKPTVVLRTAFVTIHKYTGT
DKCGAETAILGINTADGGKLTKKSARPIVPEANQAVAQYSGHKKGTNGKSIPIGCMWKNNETVCPNGYVYDKPVNVRYLD
EKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREIFY

Nucleotide


Download         Length: 3090 bp        

>NTDB_id=190026 A6L49_RS04885 WP_079883358.1 924134..927223(-) (pilC) [Neisseria meningitidis strain M22819]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGCAGGCGCAAACCCGTCAATACGCTATTATCATGAACGAGGGAAACCAGCCCGAGGTACAGTGGAATGGGT
CATATTCAATAAAGGACAAAGACAGGAAGCGCGAATATACTCATCATAATCACTCACGAGGAGGAAGCTCTGTCTCATTC
AACAATAGCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGGCAA
GGTTTCCGGTTTTGATGCCGACGGGCTGAACAAGCGCGGCAATGCCGCCGGTTGGATTCGTACCACCCGCATCGCGCTGG
CAGGCTACAGCTACGAAGGTATCGTATGCAGAAGCGGCACAGGCTGTCCCAAACTTGTCTATAAAACCCGATTTTCCTTC
GATAATCCCGACTTGGTAAAAAATGCGGGCAGGCTGGATAGGCACACAGACCCAAGCCGCGAAAATTCGCCCATTTACAA
ATTGAAGGATTATCCATGGTTGGGCGTATCTTTCAATTTGGGTGCCGAGGGTACCACCAAAGATGGTAAGACAATCAACA
AATTGGTATCTTCTTTTGATGAAAAGAATAGTAGTAATAACAACCTCGTCTATACCACGGAAGGCCGCGATATTTCCTTG
GGCGACTGGCAGCGCGAAAAGACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAGGGATTAA
AGATATCACCAACAAAACAGTGCAGTTGGGTGTCTTGAGGCCGAGCATCGATGTGCGGCTGCAAAGAAATACGGGGCTTG
CCGGCTTGCTAAATTTTTGGGCTAGTTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCGGAAGTC
AAAGCAGGCCGCTGCATCAACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCCCCGCACTGACTGCCCCCGCGCT
GTGGTTCGGACCTGTGCAAAATGGTAAGATGGAGATGTATTCCGCTTCGGTTTCTACCTACCCCGACAGTTCGAGCAGCC
GCATCTTCCTTCAAAATCTGAAAAGAAAAAACGACCCCAACAAACCCGGCCGCTATTCCCTCGCAACCTTGAATAAGTCG
GATATTGAAAGTCGAGAGCCGACTTTCACAGGGCGGCAAACCGTCATCCGATTGGATAAAGGCGTACATCAGATCAAACT
TAAAGGCAATGAGGTCGAAGGTTTTAAGGGAAACAACGGCAACGACACTTTCGGCATTGTTAGTGAAGGGAGCTTCATGC
CTGATGACAGCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTGTCAATGACGATCAATTTAAAACATTCAAC
AAAGAAGAAAAAAACGGCAAGCCAAAATACAGTCAAAAATACCGCAGCCGCGACAACGGCAAGCACGAGCGCAATTTGGG
CGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCA
AAAAAGGCAACGGGGACGCGCGCAACTATAGTCTGAAGCTCAGTTATATCCCGGGCACGATGCCGCGCAAGGATATTCAA
AACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGG
CGGCTTTGTCTTGCGCCAAGTTAACAACTTAAATGGGCAAGACCGCGTGTTTATGTTCGGCGCGATGGGCTTTGGCGGCA
GAGGCGCATACGCCTTGGATTTGACCAAAGCCGACAGCAATAACCCGACCGCCGTTTCCCTGTTTGATGTCAAAAATGAC
AAAAATAAAGGCAATAATAGTGCAGAATTAGGCTACACCGTCGGCACACCGCAAATCGGCAAAACCCACGACGGCAAATA
CGCCGCTTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACGACCAACAAAATAAAACCGCGCTGTATGTGTATGATT
TGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGAT
AAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGATTTGAGCGGTCA
AGATCCTAATCAATGGTCTGTACGCACCATTTTCAGCGGCAACAAACCGATTACTTCCGCACCCGCCATTTCCCAACTGA
AAGACAAACGCGTGGTTATCTTCGGTACGGGCAGTGATTTGAGTGAGGAAGATGTTGATAATAATGATATACAATCTATT
TACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAACGGGCTGCTCGAGCAAGTGCTGAA
AAAAGACGGCAATACGCTGTTCTTAAGCGACTACAAAAGGTCTAACGGCTCGGGCGATAAGGGCTGGGTAGTGAAATTGG
AAGCCGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCATAAATATACGGGTACG
GACAAATGCGGCGCGGAAACCGCCATTTTGGGTATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCC
GATTGTGCCGGAAGCCAATCAGGCTGTCGCGCAATATTCCGGTCATAAGAAAGGCACCAACGGCAAATCCATCCCTATAG
GTTGTATGTGGAAAAACAATGAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGTTATCTGGAT
GAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTC
CGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCG
GCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAATCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(506-837)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

79.003

100

0.801

Multiple sequence alignment