Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   A6L49_RS00840 Genome accession   NZ_CP016646
Coordinates   172274..172918 (-) Length   214 a.a.
NCBI ID   WP_002226073.1    Uniprot ID   A0A378VTS6
Organism   Neisseria meningitidis strain M22819     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 167274..177918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L49_RS00805 (A6L49_00805) ftsL 167644..167907 (-) 264 WP_002232818.1 cell division protein FtsL -
  A6L49_RS00810 (A6L49_00810) rsmH 167904..168890 (-) 987 WP_002229044.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
  A6L49_RS00815 (A6L49_00815) mraZ 168887..169342 (-) 456 WP_002218779.1 division/cell wall cluster transcriptional repressor MraZ -
  A6L49_RS00820 (A6L49_00820) - 169648..170838 (+) 1191 WP_050584817.1 class I SAM-dependent methyltransferase -
  A6L49_RS00835 (A6L49_00835) - 171420..172241 (-) 822 WP_002226074.1 undecaprenyl-diphosphate phosphatase -
  A6L49_RS00840 (A6L49_00840) dsbA1 172274..172918 (-) 645 WP_002226073.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  A6L49_RS00845 (A6L49_00845) ftsN 172921..173766 (-) 846 WP_002226072.1 cell division protein FtsN -
  A6L49_RS00850 (A6L49_00850) comM 173872..175368 (-) 1497 WP_002226071.1 YifB family Mg chelatase-like AAA ATPase Machinery gene
  A6L49_RS00855 (A6L49_00855) - 175382..175702 (-) 321 WP_002216505.1 accessory factor UbiK family protein -
  A6L49_RS00865 (A6L49_00865) putP 176185..177711 (+) 1527 WP_002220352.1 sodium/proline symporter PutP -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23967.99 Da        Isoelectric Point: 9.8294

>NTDB_id=190010 A6L49_RS00840 WP_002226073.1 172274..172918(-) (dsbA1) [Neisseria meningitidis strain M22819]
MKLKHLLPLLLSAVLSAQAYALTEREDYLVLDKPIPQEQSGKIEVLEFFGYFCVHCHHFDPLLLKLGKALPSDAYLRTEH
VVWQPEMLGLARMAAAVNLSGLKYQANPAVFKAVYEQKIRLENRAVAGKWALSQKGFDGKKLMRAYDSPEAAAAALKMQK
LTEQYGIDSTPTVIVGGKYRVIFNNGFDGGVHTIKELVAKVREERKRQTPAVQK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=190010 A6L49_RS00840 WP_002226073.1 172274..172918(-) (dsbA1) [Neisseria meningitidis strain M22819]
ATGAAGCTCAAACATCTGTTGCCGCTGCTGCTGTCGGCAGTGTTGTCCGCGCAGGCATATGCCCTGACGGAAAGGGAAGA
CTATCTTGTGTTGGATAAACCCATTCCTCAAGAACAGTCGGGCAAAATTGAGGTTTTGGAATTTTTCGGCTATTTCTGCG
TACATTGCCATCATTTCGATCCTTTGTTATTGAAATTGGGCAAGGCATTGCCGTCTGATGCCTATTTGAGGACGGAGCAC
GTGGTCTGGCAGCCTGAAATGCTCGGTCTGGCCAGGATGGCGGCTGCCGTCAATTTGTCGGGTTTGAAATATCAGGCAAA
CCCTGCTGTGTTTAAAGCAGTTTACGAACAAAAAATCCGCTTGGAAAACAGGGCTGTTGCCGGAAAATGGGCTTTGTCTC
AAAAAGGCTTTGACGGCAAAAAACTGATGCGCGCCTATGATTCCCCCGAAGCTGCCGCCGCCGCATTAAAAATGCAGAAA
CTGACGGAACAATACGGTATTGACAGCACGCCGACCGTTATTGTCGGCGGAAAATACCGCGTTATCTTCAATAATGGCTT
TGACGGCGGCGTTCATACGATTAAAGAATTGGTTGCCAAAGTCAGGGAAGAACGCAAGCGTCAGACCCCTGCTGTACAGA
AATAG

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(42-179)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A378VTS6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

56.684

87.383

0.495
  dsbA2 Neisseria meningitidis MC58

51.075

86.916

0.444

Multiple sequence alignment