Detailed information NTG0189670

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: B9H01_RS10220
• Genome accession: NZ_CP020863
• Coordinates: 2027567..2030107 (-)
• Length: 846 a.a.
• NCBI ID: WP_012775399.1
• Uniprot ID: A0A0H3MXU9
• Organism: Streptococcus suis strain SC19
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2022567..2035107

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B9H01_RS10200 (B9H01_10200)	-	2024929..2026218 (+)	1290	WP_012775397.1	IS4 family transposase	-
B9H01_RS10205 (B9H01_10205)	-	2026333..2026521 (-)	189	WP_014636177.1	hypothetical protein	-
B9H01_RS10210 (B9H01_10210)	-	2026555..2026995 (-)	441	WP_012027998.1	DUF3021 domain-containing protein	-
B9H01_RS10215 (B9H01_10215)	-	2026992..2027435 (-)	444	WP_012027999.1	LytTR family DNA-binding domain-containing protein	-
B9H01_RS10220 (B9H01_10220)	hexA	2027567..2030107 (-)	2541	WP_012775399.1	DNA mismatch repair protein MutS	Machinery gene
B9H01_RS10225 (B9H01_10225)	argR	2030122..2030562 (-)	441	WP_002937036.1	arginine repressor	-
B9H01_RS10230 (B9H01_10230)	argS	2030669..2032357 (+)	1689	WP_012028003.1	arginine--tRNA ligase	-
B9H01_RS10235 (B9H01_10235)	-	2032537..2033451 (+)	915	WP_012775400.1	SH3 domain-containing protein	-
B9H01_RS10240 (B9H01_10240)	-	2033504..2034025 (-)	522	WP_012775401.1	hypothetical protein	-
B9H01_RS10245 (B9H01_10245)	-	2034137..2034319 (+)	183	WP_002937045.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95116.55 Da
• Isoelectric Point: 4.8252

>NTDB_id=189670 B9H01_RS10220 WP_012775399.1 2027567..2030107(-) (hexA) [Streptococcus suis strain SC19]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTHPAPSVV
EEPSGQLDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=189670 B9H01_RS10220 WP_012775399.1 2027567..2030107(-) (hexA) [Streptococcus suis strain SC19]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAATTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAAAATCCGATTCCCATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTACAGTTCGCGCTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAGATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAGGATGAGGTGACGGAAGATGTCCAGCTGATTGACAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCAGGTAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTCCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGCTAGACGAAACTAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGATCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGTTTGGCCAGCCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTTTGGGAAATATCCCAGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATTTGGTGGCTGGATTGGACCCAATCCCAGAACTGCACGCTCTCATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTATCGTCTAGTCAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCATCTGGTATCAATAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTTACCAATTCCAATCTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATTGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATAGGTCGCTTGCAGAAGCTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCGATACACATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGAC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACCCGAATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCGGTCCGTCTGGCGACAGATCGGTCGCTCATCCTCTTTGATGAGTTGGGACGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCATGACAAGATTGGTGCCAAGACTCTCTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACTTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAT
TGCAGCGGGCAGATCGGATTTTGCAGACGCTTGAAAACCAAGCCCCTACTGCACCAACTCACCCAGCTCCGTCAGTAGTG
GAAGAACCGTCAGGTCAACTTGATCTCTTCGCAGACACGCCTTCTCACCCAGTACTTGATGAACTGGAAAAACTAGACAT
CTACAATATGACCCCTATGGAAGTCATGATGGCGGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

3D structure

• AlphaFold DB: A0A0H3MXU9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.877	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	37.762	100	0.383