Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   B7474_RS04190 Genome accession   NZ_CP020714
Coordinates   828905..829624 (-) Length   239 a.a.
NCBI ID   WP_001217723.1    Uniprot ID   -
Organism   Staphylococcus aureus strain K18     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 823905..834624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B7474_RS04170 (B7474_04155) - 824288..824653 (+) 366 WP_000214070.1 truncated hemoglobin YjbI -
  B7474_RS04175 (B7474_04160) yjbH 824676..825482 (+) 807 WP_000896697.1 protease adaptor protein YjbH -
  B7474_RS04180 (B7474_04165) pepF 825942..827750 (-) 1809 WP_000082725.1 oligoendopeptidase F Regulator
  B7474_RS04185 (B7474_04170) coiA 827798..828784 (-) 987 WP_101766634.1 competence protein CoiA Machinery gene
  B7474_RS04190 (B7474_04175) mecA 828905..829624 (-) 720 WP_001217723.1 adaptor protein MecA Regulator
  B7474_RS04195 (B7474_04180) spxA 829995..830390 (-) 396 WP_000258003.1 transcriptional regulator SpxA -
  B7474_RS04200 (B7474_04185) trpS 830685..831674 (+) 990 WP_000448943.1 tryptophan--tRNA ligase -
  B7474_RS04205 (B7474_04190) opp4C 831716..832596 (-) 881 Protein_804 oligopeptide ABC transporter permease -
  B7474_RS04210 (B7474_04195) opp4B 832608..833570 (-) 963 WP_000239820.1 oligopeptide ABC transporter permease -
  B7474_RS04215 (B7474_04200) - 833563..834543 (-) 981 WP_000427769.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 239 a.a.        Molecular weight: 28285.17 Da        Isoelectric Point: 4.1548

>NTDB_id=189304 B7474_RS04190 WP_001217723.1 828905..829624(-) (mecA) [Staphylococcus aureus strain K18]
MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSMMDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKN
EDMMNMSDDDATDQFDEQVQELLAQTLEGEDQLEELFDQRTKEKEAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHS
NPITTEFEDLLYMVDGTYYYAVHFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYAKIIMSHNVTAQVRRYFPETTE

Nucleotide


Download         Length: 720 bp        

>NTDB_id=189304 B7474_RS04190 WP_001217723.1 828905..829624(-) (mecA) [Staphylococcus aureus strain K18]
ATGAGAATAGAACGAGTAGATGATACAACTGTAAAATTGTTTATAACATATAGCGATATCGAGGCCCGTGGATTTAGTCG
TGAAGATTTATGGACAAATCGCAAACGTGGCGAAGAATTCTTTTGGTCAATGATGGATGAAATTAACGAAGAAGAAGATT
TTGTTGTAGAAGGTCCATTATGGATTCAAGTACATGCCTTTGAAAAAGGTGTCGAAGTCACAATTTCTAAATCTAAAAAT
GAAGATATGATGAATATGTCTGATGATGATGCAACTGATCAATTTGATGAACAAGTTCAAGAATTGTTAGCTCAAACATT
AGAAGGTGAAGATCAATTAGAAGAATTATTCGATCAACGAACAAAAGAAAAAGAAGCTCAAGGTTCTAAACGTCAAAAGT
CTTCAGCACGTAAAAATACAAGAACAATTATTGTGAAATTTAACGATTTAGAAGATGTTATTAATTATGCATATCATAGC
AATCCAATAACTACAGAGTTTGAAGATTTGTTATATATGGTTGATGGTACTTATTATTATGCTGTACATTTTGATAGTCA
TGTTGATCAAGAAGTCATTAATGATAGTTACAGTCAATTGCTTGAATTTGCTTATCCAACAGACAGAACAGAAGTTTATT
TAAATGACTATGCTAAAATAATTATGAGTCATAACGTAACAGCTCAAGTTCGACGTTATTTTCCAGAGACAACTGAATAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

37.975

99.163

0.377