Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   B7473_RS08900 Genome accession   NZ_CP020713
Coordinates   1769257..1769976 (+) Length   239 a.a.
NCBI ID   WP_001217723.1    Uniprot ID   -
Organism   Staphylococcus aureus strain K17     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1764257..1774976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B7473_RS08875 (B7473_08865) - 1764338..1765318 (+) 981 WP_000427769.1 ABC transporter ATP-binding protein -
  B7473_RS08880 (B7473_08870) opp4B 1765311..1766273 (+) 963 WP_000239820.1 oligopeptide ABC transporter permease -
  B7473_RS08885 (B7473_08875) opp4C 1766285..1767165 (+) 881 Protein_1689 oligopeptide ABC transporter permease -
  B7473_RS08890 (B7473_08880) trpS 1767207..1768196 (-) 990 WP_000448943.1 tryptophan--tRNA ligase -
  B7473_RS08895 (B7473_08885) spxA 1768491..1768886 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  B7473_RS08900 (B7473_08890) mecA 1769257..1769976 (+) 720 WP_001217723.1 adaptor protein MecA Regulator
  B7473_RS08905 (B7473_08895) coiA 1770097..1771083 (+) 987 WP_101766634.1 competence protein CoiA Machinery gene
  B7473_RS08910 (B7473_08900) pepF 1771131..1772939 (+) 1809 WP_000082725.1 oligoendopeptidase F Regulator
  B7473_RS08915 (B7473_08905) yjbH 1773399..1774205 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  B7473_RS08920 (B7473_08910) - 1774228..1774593 (-) 366 WP_000214070.1 truncated hemoglobin YjbI -

Sequence

Protein


Download         Length: 239 a.a.        Molecular weight: 28285.17 Da        Isoelectric Point: 4.1548

>NTDB_id=189240 B7473_RS08900 WP_001217723.1 1769257..1769976(+) (mecA) [Staphylococcus aureus strain K17]
MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSMMDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKN
EDMMNMSDDDATDQFDEQVQELLAQTLEGEDQLEELFDQRTKEKEAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHS
NPITTEFEDLLYMVDGTYYYAVHFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYAKIIMSHNVTAQVRRYFPETTE

Nucleotide


Download         Length: 720 bp        

>NTDB_id=189240 B7473_RS08900 WP_001217723.1 1769257..1769976(+) (mecA) [Staphylococcus aureus strain K17]
ATGAGAATAGAACGAGTAGATGATACAACTGTAAAATTGTTTATAACATATAGCGATATCGAGGCCCGTGGATTTAGTCG
TGAAGATTTATGGACAAATCGCAAACGTGGCGAAGAATTCTTTTGGTCAATGATGGATGAAATTAACGAAGAAGAAGATT
TTGTTGTAGAAGGTCCATTATGGATTCAAGTACATGCCTTTGAAAAAGGTGTCGAAGTCACAATTTCTAAATCTAAAAAT
GAAGATATGATGAATATGTCTGATGATGATGCAACTGATCAATTTGATGAACAAGTTCAAGAATTGTTAGCTCAAACATT
AGAAGGTGAAGATCAATTAGAAGAATTATTCGATCAACGAACAAAAGAAAAAGAAGCTCAAGGTTCTAAACGTCAAAAGT
CTTCAGCACGTAAAAATACAAGAACAATTATTGTGAAATTTAACGATTTAGAAGATGTTATTAATTATGCATATCATAGC
AATCCAATAACTACAGAGTTTGAAGATTTGTTATATATGGTTGATGGTACTTATTATTATGCTGTACATTTTGATAGTCA
TGTTGATCAAGAAGTCATTAATGATAGTTACAGTCAATTGCTTGAATTTGCTTATCCAACAGACAGAACAGAAGTTTATT
TAAATGACTATGCTAAAATAATTATGAGTCATAACGTAACAGCTCAAGTTCGACGTTATTTTCCAGAGACAACTGAATAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

37.975

99.163

0.377