Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   BBW65_RS01400 Genome accession   NZ_CP016503
Coordinates   298232..299911 (+) Length   559 a.a.
NCBI ID   WP_066338716.1    Uniprot ID   A0A1B1U4B3
Organism   Helicobacter enhydrae strain MIT 01-6242     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 293232..304911
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BBW65_RS07775 - 294187..294408 (-) 222 WP_083985973.1 prephenate dehydratase domain-containing protein -
  BBW65_RS01385 (BBW65_01385) guaA 294513..296081 (-) 1569 WP_066338706.1 glutamine-hydrolyzing GMP synthase -
  BBW65_RS01390 (BBW65_01390) - 296158..297615 (-) 1458 WP_066338709.1 L-aspartate oxidase -
  BBW65_RS01395 (BBW65_01395) - 297783..298235 (+) 453 WP_199919449.1 hypothetical protein -
  BBW65_RS01400 (BBW65_01400) uvrC 298232..299911 (+) 1680 WP_066338716.1 excinuclease ABC subunit UvrC Machinery gene
  BBW65_RS01405 (BBW65_01405) - 299952..301094 (+) 1143 WP_199919450.1 hypothetical protein -
  BBW65_RS01410 (BBW65_01410) - 301077..302354 (-) 1278 WP_083985975.1 ComEC/Rec2 family competence protein -
  BBW65_RS01415 (BBW65_01415) - 302344..303300 (-) 957 WP_199919451.1 hypothetical protein -
  BBW65_RS01420 (BBW65_01420) - 303399..303893 (+) 495 WP_066338723.1 peptidylprolyl isomerase -

Sequence

Protein


Download         Length: 559 a.a.        Molecular weight: 65082.64 Da        Isoelectric Point: 9.8723

>NTDB_id=188673 BBW65_RS01400 WP_066338716.1 298232..299911(+) (uvrC) [Helicobacter enhydrae strain MIT 01-6242]
MNPKPHLTATLKNLPKKSGIYQYYDHKGHLLYIGKAKNLFNRIRSYFRISDGTPNKQLSPRIYNMVLKIETIKIIIVDNQ
TDALILENSLIKQLKPRYNILLRDDKTYPYIFFDLSQPFPRPQITRIKRTQKQLEYFGPFTQGARDILQSLYELLPLVQK
SSCPKEKKACLFFQINRCKAPCENKITPSEYAIFVQQAIAYLKDKRTLIKQLEEKMQTLASQERFERALILRDRIAKIST
LEIQTPIDLHQKNAQWDIFYLMHEARRAVLLKLYMRNGKIIASDYERFSLQYPLLSLEDETTIYQQAIINHYQKNLPLPP
QTLLLPKHLSDGLSECQQWLKESQKIDIVFPQKGIKAQLLQLAKENAQEQLKIQDEESPIKEALKDLCELTALPHKIEVF
DTSHHNGAHNVGAMIVYEDGRFLKSAYRHYMLEGSDESSQMREMLTRRAKDFERSSPPDLWLLDGGVAQIHIAQEVLESA
GVHIDIVAIAKEKLDAKAHRAKGRAKDILRAYIDTQCKSFALLPSDKRLQFCQKLRDEAHRFAINFHRKKKLQSFIPKL

Nucleotide


Download         Length: 1680 bp        

>NTDB_id=188673 BBW65_RS01400 WP_066338716.1 298232..299911(+) (uvrC) [Helicobacter enhydrae strain MIT 01-6242]
ATGAATCCCAAACCCCATCTCACCGCCACACTCAAAAATCTACCCAAAAAAAGTGGCATCTATCAATACTACGACCACAA
AGGGCATTTGCTCTACATAGGCAAAGCCAAAAACCTCTTTAACCGCATCAGGAGTTATTTCCGTATCAGCGATGGCACAC
CCAACAAGCAATTAAGTCCAAGGATCTACAATATGGTGCTAAAAATCGAAACGATCAAAATCATCATCGTTGATAACCAA
ACAGACGCCTTGATTTTGGAAAACTCTCTCATCAAACAACTCAAGCCGCGTTACAACATTTTGCTCCGAGATGACAAAAC
CTATCCTTATATTTTCTTTGATTTAAGTCAGCCATTCCCCCGTCCTCAAATCACAAGAATCAAACGCACCCAAAAACAAC
TAGAATATTTCGGACCCTTCACTCAAGGTGCAAGAGATATTCTCCAAAGCCTTTATGAGCTCCTCCCACTTGTGCAAAAA
AGCAGTTGCCCCAAAGAAAAAAAAGCCTGTCTGTTTTTCCAAATCAATCGTTGCAAAGCCCCGTGCGAAAACAAAATCAC
CCCTAGTGAATATGCCATTTTTGTCCAACAAGCCATCGCTTATCTCAAAGACAAACGCACCCTCATCAAGCAACTAGAGG
AAAAAATGCAGACACTAGCTTCACAAGAGAGGTTTGAAAGGGCTTTGATTTTGAGGGATAGGATTGCAAAAATTAGCACC
CTAGAGATTCAAACCCCGATTGATTTGCACCAAAAAAATGCACAATGGGATATTTTCTATCTTATGCATGAGGCTAGAAG
GGCGGTATTGCTCAAGCTCTATATGCGTAATGGAAAAATCATCGCAAGTGATTATGAGAGGTTTTCTCTGCAATACCCAC
TCCTCTCTCTCGAAGATGAAACAACCATCTACCAACAAGCCATCATCAATCATTACCAAAAAAATCTCCCCCTACCCCCA
CAAACGCTACTTCTGCCCAAACATCTATCAGATGGATTGTCAGAGTGCCAACAATGGCTCAAAGAGAGCCAAAAAATCGA
TATTGTTTTTCCACAAAAAGGCATCAAAGCACAGCTTCTACAACTTGCCAAAGAAAATGCCCAAGAACAATTAAAAATCC
AAGATGAAGAATCCCCTATCAAAGAAGCGCTCAAAGATTTGTGCGAACTGACTGCATTGCCACACAAAATCGAGGTTTTT
GACACAAGTCATCACAATGGAGCTCACAATGTCGGAGCGATGATCGTCTATGAAGATGGGAGATTCCTCAAAAGTGCCTA
TCGCCATTATATGCTAGAAGGAAGCGATGAGTCTTCCCAAATGCGTGAGATGCTCACGCGTCGTGCCAAAGATTTTGAGC
GTTCCTCTCCTCCAGATTTGTGGCTCCTTGATGGAGGGGTCGCACAAATCCATATCGCACAAGAAGTCTTGGAGAGTGCA
GGAGTGCATATCGATATAGTCGCGATTGCCAAAGAAAAACTTGATGCCAAAGCACATCGTGCCAAAGGGAGGGCAAAAGA
CATCTTGCGTGCTTACATCGACACCCAGTGCAAAAGCTTCGCTTTGCTTCCAAGCGATAAGCGATTGCAGTTTTGCCAAA
AGCTAAGAGATGAGGCACATCGTTTCGCAATCAATTTTCATCGCAAGAAAAAACTTCAGAGCTTCATCCCAAAGCTTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(207-239)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(386-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1B1U4B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

52.878

99.463

0.526

Multiple sequence alignment